2017
Activity of Retrotransposons in Stem Cells and Differentiated Cells
Macia A, Tejwani L, Mesci P, Muotri A, Garcia-Perez J. Activity of Retrotransposons in Stem Cells and Differentiated Cells. 2017, 127-156. DOI: 10.1007/978-3-319-48344-3_6.Peer-Reviewed Original ResearchTransposable elementsSelfish DNAHuman genomeTE insertionsEarly embryonic developmental stagesActivity of TEsActivity of retrotransposonsActivity of L1New TE insertionsEmbryonic developmental stagesHuman transposable elementsMammalian genomesGenome stabilityEukaryotic genomesNew genesGenomic regulationGenomic rearrangementsGenomeLINE-1sDifferentiated cellsGerm cellsDevelopmental stagesMobile elementsNew copiesStem cells
2016
Genome Editing in Stem Cells
Tejwani L, Trujillo C, Thomas C, Muotri A. Genome Editing in Stem Cells. 2016, 287-309. DOI: 10.1007/978-3-319-30582-0_17.Peer-Reviewed Original ResearchGenome editingCRISPR/Cas9 systemPost-transcriptional levelPotential genetic therapyWild-type formStudy of geneticsGene functionGenetic functionsHuman genomeDeleterious mutationsParticular genesReverse geneticsCRISPR/Cas9 systemCellular phenomenaGenomeMolecular biologyCellular levelStem cellsEase of programmabilityMonogenic diseasesGenesEditingGeneticsSpecific modifications