2024
Immediate and long‐term management practices of acute symptomatic seizures and epileptiform abnormalities: A cross‐sectional international survey
Punia V, Daruvala S, Dhakar M, Zafar S, Rubinos C, Ayub N, Hirsch L, Sivaraju A, investigators F. Immediate and long‐term management practices of acute symptomatic seizures and epileptiform abnormalities: A cross‐sectional international survey. Epilepsia 2024, 65: 909-919. PMID: 38358383, DOI: 10.1111/epi.17915.Peer-Reviewed Original ResearchAnti-seizure medicationsEpileptiform abnormalitiesAcute symptomatic seizuresAcute brain injuryContinuous EEGSecondary prophylaxisSymptomatic seizuresSporadic epileptiform dischargesLateralized periodic dischargesCross-sectional international surveyOutpatient follow-upAnti-seizure medication useOptimal care pathwayDose escalationBrain injuryDose changesLong-term managementElectrographic seizuresEpileptiform dischargesFollow-upAncillary testsReal-world practiceRecommended durationContinuous electroencephalographyHospital discharge
2021
Anti-seizure medications and efficacy against focal to bilateral tonic-clonic seizures: A systematic review with relevance for SUDEP prevention
Cutillo G, Tolba H, Hirsch LJ. Anti-seizure medications and efficacy against focal to bilateral tonic-clonic seizures: A systematic review with relevance for SUDEP prevention. Epilepsy & Behavior 2021, 117: 107815. PMID: 33640562, DOI: 10.1016/j.yebeh.2021.107815.Peer-Reviewed Original ResearchConceptsAnti-seizure medicationsBilateral tonic-clonic seizuresTonic-clonic seizuresSUDEP preventionSystematic reviewPlacebo-controlled clinical trialFocal impaired awareness seizuresRisk of SUDEPSudden unexpected deathMajor risk factorAwareness seizuresRisk factorsClinical trialsUnexpected deathFBTCSHigh dosesSeizuresStrong associationSUDEPPreventionMedicationsTiagabineEfficacyLamotrigineBrivaracetam
2016
Treatment of Convulsive Status Epilepticus
Grover EH, Nazzal Y, Hirsch LJ. Treatment of Convulsive Status Epilepticus. Current Treatment Options In Neurology 2016, 18: 11. PMID: 26920416, DOI: 10.1007/s11940-016-0394-5.Peer-Reviewed Original ResearchAnti-epileptic drugsNon-convulsive SEStatus epilepticusRefractory SEPreferred second-line agentNon-convulsive status epilepticusAnti-seizure medicationsHome rescue medicationThird-line agentsAcute side effectsConvulsive status epilepticusFirst-line treatmentNon-convulsive seizuresSecond-line agentsLower health care costsEmergency room visitsImmuno-modulatory agentsRecovery of consciousnessUse of benzodiazepinesQuality of lifeHealth care costsConsecutive seizuresParaneoplastic etiologyRescue medicationBuccal midazolam
2006
Advances in the Management of Seizures and Status Epilepticus in Critically Ill Patients
Khaled K, Hirsch LJ. Advances in the Management of Seizures and Status Epilepticus in Critically Ill Patients. Critical Care Clinics 2006, 22: 637-659. PMID: 17239748, DOI: 10.1016/j.ccc.2006.06.004.Peer-Reviewed Original ResearchConceptsStatus epilepticusIll patientsAnti-seizure medicationsFirst-line treatmentManagement of seizuresOrgan transplant patientsRenal failure patientsReversal of factorsSystemic sequelaeTransplant patientsFailure patientsSeizure thresholdEarly recognitionElectroencephalogram monitoringMaximal responseSpecific treatmentPatientsMetabolic imbalanceEpilepticusMedicationsSeizuresTreatmentSequelaeFeverHypoxia