Lauren Pischel, MD, MSc
Instructor of Medicine (Infectious Diseases)Cards
Additional Titles
Affiliated Faculty, Yale Institute for Global Health
Contact Info
Appointments
Additional Titles
Affiliated Faculty, Yale Institute for Global Health
Contact Info
Appointments
Additional Titles
Affiliated Faculty, Yale Institute for Global Health
Contact Info
About
Titles
Instructor of Medicine (Infectious Diseases)
Affiliated Faculty, Yale Institute for Global Health
Biography
Dr. Lauren Pischel obtained her undergraduate degree in biology at Brown University and worked in the lab of Dr. Jake Kurtis on the development of a pediatric malaria vaccine. She obtained her MD at Stanford where she conducted research with Dr. Julie Parsonnet on the impact of an antimicrobial triclosan on the human microbiome. She then completed her internal medicine residency at Yale where she was awarded the primary care award for the Fair Haven Community Health Center. She subsequently pursued her fellowship in infectious diseases at Yale and her Master of Science in the epidemiology of infectious diseases at the Yale School of Public Health. Her research interests include the epidemiology and household transmission of COVID-19 and influenza as well estimating vaccine effectiveness using real-world data and the epidemiology emerging infectious diseases.
Appointments
Infectious Diseases
InstructorPrimary
Other Departments & Organizations
Education & Training
- MSc
- Yale, Public Health- Epidmiology of Infectious Diseases (2022)
- MD
- Stanford School of Medicine (2016)
- ScB
- Brown University, Biology (2011)
Research
Overview
Public Health Interests
ORCID
0000-0002-7697-0084
Research at a Glance
Yale Co-Authors
Publications Timeline
Kavin Patel
Richard A Martinello, MD
Albert Ko, MD
George Goshua, MD, MSc, FACP
Inci Yildirim, MD, PhD, MSc
Alfred Lee, MD, PhD
Publications
2025
Social mixing patterns of United States healthcare personnel at a quaternary health center: a prospective observational study
Pischel L, Aguolu O, Ahmed N, Campbell M, Borg R, Duckwall C, Willebrand K, Zaleski A, Paintsil E, Muenker M, Malik A, Kiti M, Warren J, Jenness S, Lopman B, Belsky J, Martinello R, Yildirim I, Ko A, Omer S. Social mixing patterns of United States healthcare personnel at a quaternary health center: a prospective observational study. Infection Control And Hospital Epidemiology 2025, 46: 289-297. PMID: 39880795, PMCID: PMC11883655, DOI: 10.1017/ice.2024.234.Peer-Reviewed Original ResearchConceptsHealthcare personnelUnited States healthcare systemStates healthcare systemCOVID-19 pandemicNurse aidesContact diariesHealth centersHealthcare systemWorking-age populationImaging technologistsLow-contact groupNursesRegression modelsPandemic responseWork environmentSocial contactCOVID-19Job typeThree-hundredWorking daysDiaryParticipantsPersonnelInfectious disease transmissionContact groupP-271. Contact Patterns of United States Health Care Workers at Quaternary Health Center: Stability of contacts during the post-pandemic era
Pischel L, Aguolu O, Ahmed N, Campbell M, Borg R, Duckwall C, Willebrand K, Paintsil E, Muenker M, Malik A, Kiti M, Jenness S, Lopman B, Belsky J, Martinello R, Yildirim I, Ko A, Omer S. P-271. Contact Patterns of United States Health Care Workers at Quaternary Health Center: Stability of contacts during the post-pandemic era. Open Forum Infectious Diseases 2025, 12: ofae631.475. PMCID: PMC11777566, DOI: 10.1093/ofid/ofae631.475.Peer-Reviewed Original ResearchConceptsHealth care workersHealth care worker participationCare workersUnited States health care systemStates health care systemAge rangeHealth care systemHealth care workers' contactsLinear regressionHealth centersCare systemChi-square testCOVID-19 pandemic responseContact diariesEpidemiological researchParticipants' jobsWorking-age populationWorking ageConfidence intervalsImaging technologistsParticipantsPandemic responseSocial workersWork environmentWorking days
2024
Comprehensive profiling of social mixing patterns in resource poor countries: A mixed methods research protocol
Aguolu O, Kiti M, Nelson K, Liu C, Sundaram M, Gramacho S, Jenness S, Melegaro A, Sacoor C, Bardaji A, Macicame I, Jose A, Cavele N, Amosse F, Uamba M, Jamisse E, Tchavana C, Briones H, Jarquín C, Ajsivinac M, Pischel L, Ahmed N, Mohan V, Srinivasan R, Samuel P, John G, Ellington K, Joaquim O, Zelaya A, Kim S, Chen H, Kazi M, Malik F, Yildirim I, Lopman B, Omer S. Comprehensive profiling of social mixing patterns in resource poor countries: A mixed methods research protocol. PLOS ONE 2024, 19: e0301638. PMID: 38913670, PMCID: PMC11195963, DOI: 10.1371/journal.pone.0301638.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsLow-and-middle-income countriesData collection toolHousehold membersBurden of communicable diseasesCollection toolLow-and-middle-incomeDisease prevention strategiesInteraction dataPatterns of social mixingSocial mixingParameterizing mathematical modelsResource poor countriesPoor countriesCognitive interviewsLMIC populationsDisproportionate burdenQuantitative dataCommunicable diseasesStudy sitesPrevention strategiesContact diariesGroup discussionsStudy proceduresStudy toolDisease modelsVaccine effectiveness of 3rd generation mpox vaccines against mpox and disease severity: A systematic review and meta-analysis
Pischel L, Martini B, Yu N, Cacesse D, Tracy M, Kharbanda K, Ahmed N, Patel K, Grimshaw A, Malik A, Goshua G, Omer S. Vaccine effectiveness of 3rd generation mpox vaccines against mpox and disease severity: A systematic review and meta-analysis. Vaccine 2024, 42: 126053. PMID: 38906763, DOI: 10.1016/j.vaccine.2024.06.021.Peer-Reviewed Original ResearchConceptsPost-exposure prophylaxisMVA-BNVaccine effectivenessMeta-analysisTime of administrationNewcastle-Ottawa ScaleRisk of publication biasMeasuring vaccine efficacyImmortal time biasImmunogenicity studiesNewcastle-OttawaWeb of ScienceVaccine efficacyAnimal studiesEgger's testDisease severityFunnel plotPrimary searchDosePublication biasStudy qualityVaccineSystematic reviewVaccination timingMpox outbreakCharacterizing healthcare personnel attitudes toward receipt of a voluntary bivalent COVID-19 booster vaccine during a COVID-19 outbreak at a behavioral health hospital in Connecticut
Roberts S, Willebrand K, Fredrick J, Pischel L, Patel K, Murray T, Martinello R. Characterizing healthcare personnel attitudes toward receipt of a voluntary bivalent COVID-19 booster vaccine during a COVID-19 outbreak at a behavioral health hospital in Connecticut. Antimicrobial Stewardship & Healthcare Epidemiology 2024, 4: e87. PMID: 38774120, PMCID: PMC11106727, DOI: 10.1017/ash.2024.78.Peer-Reviewed Original Research
2023
Characterizing healthcare worker attitudes toward the bivalent COVID-19 booster
Willebrand K, Fredrick J, Pischel L, Patel K, Roberts S, Murray T, Martinello R. Characterizing healthcare worker attitudes toward the bivalent COVID-19 booster. Antimicrobial Stewardship & Healthcare Epidemiology 2023, 3: s56-s57. PMCID: PMC10594485, DOI: 10.1017/ash.2023.300.Peer-Reviewed Original ResearchConceptsBooster doseBehavioral health unitHealthcare workersHealth unitsCOVID-19COVID-19 outbreakInpatient behavioral health unitFirst booster dosePrimary vaccination seriesCOVID-19 vaccinationCOVID-19 exposureBehavioral health settingsMonovalent vaccinationVaccination seriesBooster dosesBooster vaccineComplete responsePrevious vaccinationVaccine uptakeHealth HospitalGeneral populationSide effectsPsychiatric hospitalHealth settingsDemographic data
2022
Serum Neutralizing Antibody Titers 12 Months After Coronavirus Disease 2019 Messenger RNA Vaccination: Correlation to Clinical Variables in an Adult, US Population
Zhao M, Slotkin R, Sheth AH, Pischel L, Kyriakides TC, Emu B, McNamara C, Shi Q, Delgobbo J, Xu J, Marhoffer E, Mercer-Falkoff A, Holleck J, Ardito D, Sutton RE, Gupta S. Serum Neutralizing Antibody Titers 12 Months After Coronavirus Disease 2019 Messenger RNA Vaccination: Correlation to Clinical Variables in an Adult, US Population. Clinical Infectious Diseases 2022, 76: e391-e399. PMID: 35639598, PMCID: PMC9278145, DOI: 10.1093/cid/ciac416.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsMonth postboosterRNA vaccinationClinical variablesNeutralization responseEnd-stage renal diseaseBooster dose responsePrimary series vaccinationPrimary vaccine seriesMultiple clinical factorsSystemic steroid useDoses of vaccinePrior COVID-19Maximal inhibitory concentration valuesHalf maximal inhibitory concentration (IC50) valuesSeries vaccinationVaccine seriesVaccine regimensClinical factorsDiabetes mellitusRenal diseaseComorbid conditionsSteroid useCOVID infectionImmune responseUS populationRainfall and other meteorological factors as drivers of urban transmission of leptospirosis
Cunha M, Costa F, Ribeiro GS, Carvalho MS, Reis RB, Nery N, Pischel L, Gouveia EL, Santos AC, Queiroz A, Wunder EA, Reis MG, Diggle PJ, Ko AI. Rainfall and other meteorological factors as drivers of urban transmission of leptospirosis. PLOS Neglected Tropical Diseases 2022, 16: e0007507. PMID: 35404948, PMCID: PMC9022820, DOI: 10.1371/journal.pntd.0007507.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsCost‐effectiveness of second‐line therapies in adults with chronic immune thrombocytopenia
Goshua G, Sinha P, Kunst N, Pischel L, Lee AI, Cuker A. Cost‐effectiveness of second‐line therapies in adults with chronic immune thrombocytopenia. American Journal Of Hematology 2022, 98: 122-130. PMID: 35147241, PMCID: PMC9365880, DOI: 10.1002/ajh.26497.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsThrombopoietin receptor agonistsChronic immune thrombocytopeniaSecond-line therapyImmune thrombocytopeniaEarly useCurrent practice trendsProbabilistic sensitivity analysesCost-effective treatmentFirst cost-effectiveness analysisCost-effectiveness analysisU.S. health systemLack of evidenceEarly splenectomyHematology (ASH) guidelinesReceptor agonistCurrent guidelinesSplenectomyClinical practicePractice trendsTherapyHealth systemCost-effective strategyRituximabThrombocytopeniaAmerican SocietyAdenovirus-Based Vaccines and Thrombosis in Pregnancy: A Systematic Review and Meta-analysis
Pischel L, Patel KM, Goshua G, Omer SB. Adenovirus-Based Vaccines and Thrombosis in Pregnancy: A Systematic Review and Meta-analysis. Clinical Infectious Diseases 2022, 75: 1179-1186. PMID: 35134164, PMCID: PMC9383370, DOI: 10.1093/cid/ciac080.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsAdenovirus-vectored vaccinePregnant womenVector vaccinesSystematic reviewGeneral populationAdenovirus vector-based vaccinesClinical trial populationsVector-based vaccinesCrucial risk factorVaccine recipientsHypercoagulable stateTrial populationRisk factorsClinical trialsJohnson vaccineRare caseVaccine componentsThrombocytopeniaVaxzevria vaccineMeta-AnalysisVaccine developmentVaccinePotential associationCoagulopathyInfectious diseases
Academic Achievements & Community Involvement
honor Janeway Society Member
Yale School of Medicine AwardDetails10/10/2024
News
News
- December 25, 2024Source: SELF
Walking Pneumonia Is on the Rise. Here Are the Symptoms to Look Out For
- July 27, 2022
New Appointments & Promotions Within Department of Internal Medicine
- April 14, 2022
Discoveries & Impact (April 2022)
- December 02, 2020
Infectious Disease Fellowship Supports Doctor’s Research