2001
A HERV-K provirus in chimpanzees, bonobos and gorillas, but not humans
Barbulescu M, Turner G, Su M, Kim R, Jensen-Seaman M, Deinard A, Kidd K, Lenz J. A HERV-K provirus in chimpanzees, bonobos and gorillas, but not humans. Current Biology 2001, 11: 779-783. PMID: 11378389, DOI: 10.1016/s0960-9822(01)00227-5.Peer-Reviewed Original ResearchConceptsTransposable genetic elementsDNA sequencing studiesHERV-K provirusesUnique insertion sitesAfrican great apesChimpanzee genomeEvolutionary separationPhylogenetic relationshipsOrthologous positionsCommon ancestorHuman genomeModern speciesPreintegration siteGenetic elementsSequencing studiesGenomeEndogenous retrovirusesHuman evolutionGreat apesLineagesGorillasSpeciesHERVInsertion siteChimpanzeesRace, Genes and Human Origins: How Genetically Diverse Are We?
Kidd K. Race, Genes and Human Origins: How Genetically Diverse Are We? 2001, 11-24. DOI: 10.1007/978-1-4615-1591-3_2.Peer-Reviewed Original Research
2000
Transmission/Disequilibrium Tests Using Multiple Tightly Linked Markers
Zhao H, Zhang S, Merikangas K, Trixler M, Wildenauer D, Sun F, Kidd K. Transmission/Disequilibrium Tests Using Multiple Tightly Linked Markers. American Journal Of Human Genetics 2000, 67: 936-946. PMID: 10968775, PMCID: PMC1287895, DOI: 10.1086/303073.Peer-Reviewed Original Research
1999
Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans
Barbulescu M, Turner G, Seaman M, Deinard A, Kidd K, Lenz J. Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans. Current Biology 1999, 9: 861-s1. PMID: 10469592, DOI: 10.1016/s0960-9822(99)80390-x.Peer-Reviewed Original ResearchConceptsOpen reading frameFull-length open reading frameHuman genome todayReading frameFull length HERVGenome todayGenomes of humansCis-acting sequencesHERV-K provirusesViral open reading framesGorilla genomeHuman genomePrimate evolutionMouse mammary tumor virusComplete sequencingHost genomePreintegration siteHuman endogenous retrovirus KGenomeHERV-K proteinsEndogenous retrovirusesMammary tumor virusTumor virusProvirusMultiple proviruses
1997
Survey of Maximum CTG/CAG Repeat Lengths in Humans and Non-Human Primates: Total Genome Scan in Populations Using the Repeat Expansion Detection Method
Sirugo G, Deinard A, Kidd J, Kidd K. Survey of Maximum CTG/CAG Repeat Lengths in Humans and Non-Human Primates: Total Genome Scan in Populations Using the Repeat Expansion Detection Method. Human Molecular Genetics 1997, 6: 403-408. PMID: 9147643, DOI: 10.1093/hmg/6.3.403.Peer-Reviewed Original ResearchConceptsCTG/CAGPygmy chimpanzeesCommon chimpanzeesRepeat lengthRandom genetic driftOrang-utansHuman populationDisease association studiesGenetic driftHuman genomeOverall mutation rateGenome scanAssociation studiesMutation rateBiaka PygmiesExpansion mutationRepeat expansionTotal genome scanPopulation differencesPopulation stratificationNon-human primatesRepeat expansion detection (RED) methodExpansion detectionChimpanzeesMutations
1996
Chromosomal localization of long trinucleotide repeats in the human genome by fluorescence in situ hybridization
Haaf T, Sirugo G, Kidd K, Ward D. Chromosomal localization of long trinucleotide repeats in the human genome by fluorescence in situ hybridization. Nature Genetics 1996, 12: 183-185. PMID: 8563757, DOI: 10.1038/ng0296-183.Peer-Reviewed Original ResearchConceptsLong trinucleotide repeatsChromosomal localizationTrinucleotide repeatsHuman genomeNormal human genomeSitu hybridizationDifferent genetic diseasesUnstable trinucleotide repeatsChromosomal distributionTrinucleotide microsatellitesLarge repeatsAGG repeatsCCG repeatsRepeatsGenetic diseasesRepeat lociLarge CTG expansionsGenomeCTG expansionHybridizationPathological significanceMyotonic dystrophyMicrosatellitesLocalizationLoci
1990
Mapping the Human Genome: Current Status
Stephens J, Cavanaugh M, Gradie M, Mador M, Kidd K. Mapping the Human Genome: Current Status. Science 1990, 250: 237-244. PMID: 2218527, DOI: 10.1126/science.2218527.Peer-Reviewed Original ResearchLinkage relationships of human arginine vasopressin-neurophysin-II and oxytocin-neurophysin-I to prodynorphin and other loci on chromosome 20.
Summar M, Phillips J, Battey J, Castiglione C, Kidd K, Maness K, Weiffenbach B, Gravius T. Linkage relationships of human arginine vasopressin-neurophysin-II and oxytocin-neurophysin-I to prodynorphin and other loci on chromosome 20. Endocrinology 1990, 4: 947-50. PMID: 1978246, DOI: 10.1210/mend-4-6-947.Peer-Reviewed Original ResearchConceptsLinkage relationshipsChromosome 20Restriction fragment length polymorphismCentre d'Etude du Polymorphisme Humain (CEPH) collectionFragment length polymorphismShort armAnonymous DNA segmentsSomatic cell hybridsLength polymorphismDistal short armSame neurosecretory granulesStructural geneTranscriptional associationsHuman genomeCell hybridsDNA segmentsLocus mapsMultilocus linkage analysisClose physical relationshipLinkage analysisSouthern blotOdds (LOD) scoreLociGenesClose linkage
1989
One Form of Bipolar Affective Disorder is Mapped to Chromosome 11
Kidd K, Egeland J, Gerhard D, Pauls D, Sussex J, Allen C, Hostetter A, Kidd J, Pakstis A, Housman D. One Form of Bipolar Affective Disorder is Mapped to Chromosome 11. 1989, 184-187. DOI: 10.1007/978-1-4612-3524-8_41.Peer-Reviewed Original ResearchComplex human disordersGenetic linkageGenetic markersHuman disordersComplex traitsRestriction fragment length polymorphismHuman genomeFragment length polymorphismMajor locusChromosome 11Length polymorphismBipolar affective disorderGenomeLociTraitsDNAMarkersLinkageGeneticistsPolymorphismLarge numberDiscoveryFirst step