2020
Local immunosuppression in vascularized composite allotransplantation (VCA): A systematic review
Safi AF, Kauke M, Nelms L, Palmer WJ, Tchiloemba B, Kollar B, Haug V, Pomahač B. Local immunosuppression in vascularized composite allotransplantation (VCA): A systematic review. Journal Of Plastic Reconstructive & Aesthetic Surgery 2020, 74: 327-335. PMID: 33229219, DOI: 10.1016/j.bjps.2020.10.003.Peer-Reviewed Original ResearchConceptsLocal immunosuppressionSystematic reviewAllograft survivalComposite allotransplantationAllograft survival dataCell-based therapy strategiesImproved allograft survivalMain immunosuppressive agentMeta-Analyses (PRISMA) guidelinesPreclinical animal studiesPreferred Reporting ItemsMalignant side effectsImmunosuppressive agentsPreclinical dataSignificant prolongationRat modelHuman trialsExclusion criteriaImmunosuppressionSide effectsAnimal studiesReporting ItemsPubMed databaseSystemic toxicityTherapy strategies
2018
The importance of lymph node ratio for patients with mandibular infiltration of oral squamous cell carcinoma
Safi AF, Kauke M, Grandoch A, Nickenig HJ, Zöller J, Kreppel M. The importance of lymph node ratio for patients with mandibular infiltration of oral squamous cell carcinoma. Journal Of Cranio-Maxillofacial Surgery 2018, 46: 1007-1012. PMID: 29709331, DOI: 10.1016/j.jcms.2018.03.021.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCarcinoma, Squamous CellChemoradiotherapyFemaleHumansKaplan-Meier EstimateLymph Node ExcisionLymph NodesLymphatic MetastasisMaleMandibleMiddle AgedMouth NeoplasmsMultivariate AnalysisNeck DissectionNeoadjuvant TherapyNeoplasm InvasivenessNeoplasm Recurrence, LocalNeoplasm StagingPrognosisRetrospective StudiesRisk AssessmentConceptsOral squamous cell carcinomaSquamous cell carcinomaMandibular infiltrationLocoregional recurrenceCell carcinomaLymph nodesExclusion criteriaTreatment-naive oral squamous cell carcinomaImportance of lymphPathologic N classificationLymph node ratioPositive lymph nodesNegative resection marginsRetrospective chart reviewRisk stratification toolAssessment of prognosisConventional nodalT4b classificationUnresectable diseaseNeoadjuvant chemoradiotherapyPerioperative deathsSynchronous malignanciesChart reviewResection marginsClinicopathological characteristics