2021
Predicting In-Hospital Mortality in Patients Undergoing Percutaneous Coronary Intervention
Castro-Dominguez YS, Wang Y, Minges KE, McNamara RL, Spertus JA, Dehmer GJ, Messenger JC, Lavin K, Anderson C, Blankinship K, Mercado N, Clary JM, Osborne AD, Curtis JP, Cavender MA. Predicting In-Hospital Mortality in Patients Undergoing Percutaneous Coronary Intervention. Journal Of The American College Of Cardiology 2021, 78: 216-229. PMID: 33957239, DOI: 10.1016/j.jacc.2021.04.067.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionHospital mortalityQuality improvement effortsCoronary interventionDevelopment cohortValidation cohortRisk-standardized mortality ratesHospital risk-standardized mortality ratesBedside risk scoreHigh-risk patientsIn-Hospital MortalityHospital mortality riskRisk of mortalityLevel of consciousnessProcedural urgencyCathPCI RegistryClinical presentationRisk cohortRisk stratificationCardiovascular instabilityCardiac arrestMortality riskRisk scoreClinical acuityClinical relevanceDefibrillation Safety Margin Testing in Patients With Congenital Heart Disease Results From the NCDR
Prutkin JM, Wang Y, Escudero CA, Stephenson EA, Minges KE, Curtis JP, Hsu JC. Defibrillation Safety Margin Testing in Patients With Congenital Heart Disease Results From the NCDR. JACC Clinical Electrophysiology 2021, 7: 1145-1154. PMID: 33933411, DOI: 10.1016/j.jacep.2021.02.019.Peer-Reviewed Original ResearchMeSH KeywordsDefibrillators, ImplantableHeart Defects, CongenitalHospital MortalityHumansRegistriesRetrospective StudiesConceptsCongenital heart diseaseLowest successful energyHospital stayNational Cardiovascular Data Registry ICD RegistryImplantable cardioverter-defibrillator insertionVentricular septal defectTetralogy of FallotHeart disease resultHospital complicationsHospital deathHospital outcomesMultivariable adjustmentEbstein's anomalyICD RegistryICD recipientsSeptal defectCommon ventricleHeart diseaseRetrospective analysisLower oddsGreat vesselsICD proceduresDisease resultsSuccessful energyICD generator
2020
Survival Following Implantable Cardioverter‐Defibrillator Implantation in Patients With Amyloid Cardiomyopathy
Higgins AY, Annapureddy AR, Wang Y, Minges KE, Lampert R, Rosenfeld LE, Jacoby DL, Curtis JP, Miller EJ, Freeman JV. Survival Following Implantable Cardioverter‐Defibrillator Implantation in Patients With Amyloid Cardiomyopathy. Journal Of The American Heart Association 2020, 9: e016038. PMID: 32867553, PMCID: PMC7726970, DOI: 10.1161/jaha.120.016038.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillator implantationCardioverter-defibrillator implantationNonischemic cardiomyopathyCardiac amyloidosisDiabetes mellitusCerebrovascular diseaseVentricular tachycardiaMultivariable Cox proportional hazards regression modelsCox proportional hazards regression modelProportional hazards regression modelsKaplan-Meier survival curvesCox proportional hazards modelPropensity-matched cohortOutcomes of patientsHazards regression modelsProportional hazards modelCause mortalityICD implantationRenal functionMultivariable analysisConclusions MortalityRisk factorsRegistry dataAmyloid cardiomyopathyHigh riskComparison of Mortality and Readmission in Non-Ischemic Versus Ischemic Cardiomyopathy After Implantable Cardioverter-Defibrillator Implantation
Higgins AY, Bjerre J, Parzynski CS, Minges KE, Ahmad T, Desai NR, Enriquez A, Spatz ES, Friedman DJ, Curtis JP, Hlatky MA, Freeman JV. Comparison of Mortality and Readmission in Non-Ischemic Versus Ischemic Cardiomyopathy After Implantable Cardioverter-Defibrillator Implantation. The American Journal Of Cardiology 2020, 133: 116-125. PMID: 32862971, DOI: 10.1016/j.amjcard.2020.07.035.Peer-Reviewed Original ResearchConceptsNon-ischemic cardiomyopathyImplantable cardioverter defibrillator implantationCardioverter-defibrillator implantationICM patientsIschemic cardiomyopathyNational Cardiovascular Data Registry ICD RegistryCox proportional hazards regression modelPrimary prevention ICD implantationLeft ventricular ejection fractionProportional hazards regression modelsPrimary prevention ICDsRetrospective cohort studyVentricular ejection fractionKaplan-Meier curvesHazards regression modelsRisk of mortalityComparison of mortalityMedian followCohort studyICD implantationEjection fractionHeart failureHospital readmissionICD RegistryPatient subgroupsComparison of left ventricular lead upgrade vs continued medical care among patients eligible for cardiac resynchronization therapy at the time of defibrillator generator replacement: Predictors of left ventricular lead upgrade and associations with long-term outcomes
Hyman MC, Bao H, Curtis JP, Minges K, Schaller RD, Birgersdotter-Green U, Marchlinski FE, Hsu JC. Comparison of left ventricular lead upgrade vs continued medical care among patients eligible for cardiac resynchronization therapy at the time of defibrillator generator replacement: Predictors of left ventricular lead upgrade and associations with long-term outcomes. Heart Rhythm 2020, 17: 1878-1886. PMID: 32497762, DOI: 10.1016/j.hrthm.2020.05.032.Peer-Reviewed Original ResearchConceptsCardiac resynchronization therapyCRT-eligible patientsCRT upgradeResynchronization therapyClinical outcomesNational Cardiovascular Data Registry ICD RegistryGenerator replacementPeriprocedural complication rateLeft ventricular leadSubpopulation of patientsLong-term outcomesICD generator replacementHierarchical logistic regression modelsLogistic regression modelsSecondary endpointsCause mortalityPrimary endpointComplication rateICD RegistryProcedural complicationsMedical managementICD populationNational registryVentricular leadClaims dataUtilization Effects of the Affordable Care Act on Implantable Cardioverter-Defibrillator Therapy
Madias C, Parzynski CS, Burrows A, Minges KE, Curtis JP, Doukky R. Utilization Effects of the Affordable Care Act on Implantable Cardioverter-Defibrillator Therapy. Journal Of The American College Of Cardiology 2020, 75: 1714-1717. PMID: 32273036, DOI: 10.1016/j.jacc.2020.02.023.Peer-Reviewed Original ResearchPrevalence, predictors and complications with defibrillation threshold testing in pediatric patients: Results from the NCDR
Prutkin JM, Wang Y, Escudero CA, Stephenson EA, Minges KE, Curtis JP, Hsu JC. Prevalence, predictors and complications with defibrillation threshold testing in pediatric patients: Results from the NCDR. International Journal Of Cardiology 2020, 305: 44-49. PMID: 31980272, DOI: 10.1016/j.ijcard.2020.01.027.Peer-Reviewed Original ResearchMeSH KeywordsChildDefibrillators, ImplantableElectric CountershockHumansLength of StayPrevalenceRegistriesRetrospective StudiesVentricular FibrillationConceptsInadequate defibrillation safety marginDefibrillation safety marginDFT testingDefibrillation threshold testingHospital complicationsPediatric patientsHospital stayICD recipientsNational Cardiovascular Data Registry ICD RegistryThreshold testingLowest successful energyProlonged hospital stayRisk of complicationsTransvenous ICD implantationHospital dischargeICD implantationMultivariable adjustmentICD RegistryPediatric populationRetrospective analysisLower oddsComplicationsPatientsTesting useLittle dataStent selection among patients with chronic kidney disease: Results from the NCDR CathPCI Registry
Feldman DA, Shroff AR, Bao H, Curtis JP, Minges KE, Ardati AK. Stent selection among patients with chronic kidney disease: Results from the NCDR CathPCI Registry. Catheterization And Cardiovascular Interventions 2020, 96: 1213-1221. PMID: 31909543, DOI: 10.1002/ccd.28698.Peer-Reviewed Original ResearchConceptsChronic kidney diseasePercutaneous coronary interventionST-elevation myocardial infarctionDES usageBare metal stentsNCDR CathPCI RegistryCathPCI RegistryRenal functionKidney diseasePCI casesElective percutaneous coronary interventionAdvanced renal dysfunctionNormal renal functionCoronary stent placementCKD stageRenal dysfunctionCoronary interventionUse of DESMyocardial infarctionStent placementSubgroup analysisStent usageMetal stentsPatientsStent selection
2018
Characteristics and Outcomes of Pediatric Patients Who Undergo Placement of Implantable Cardioverter Defibrillators
Baskar S, Bao H, Minges KE, Spar DS, Czosek RJ. Characteristics and Outcomes of Pediatric Patients Who Undergo Placement of Implantable Cardioverter Defibrillators. Circulation Arrhythmia And Electrophysiology 2018, 11: e006542. PMID: 30354291, DOI: 10.1161/circep.118.006542.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge FactorsChildChild, PreschoolDeath, Sudden, CardiacDefibrillators, ImplantableDevice RemovalElectric CountershockFemaleHumansMalePrimary PreventionProsthesis FailureRegistriesRetrospective StudiesRisk AssessmentRisk FactorsSecondary PreventionTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsImplantable cardioverter defibrillatorPediatric patientsPediatric cohortCardioverter defibrillatorNational Cardiovascular Data Registry ICD RegistryWorse New York Heart Association classNew York Heart Association classSecondary prevention ICD implantationInhospital complication rateStructural heart diseaseSingle-chamber devicesComplication rateEbstein's anomalyICD implantationInhospital complicationsPatient characteristicsAssociation classICD recipientsICD RegistryNonischemic cardiomyopathyRetrospective reviewCardiac resynchronizationDevice implantationPrimary preventionICD implantsVentricular septal rupture complicating acute myocardial infarction: Incidence, treatment, and outcomes among medicare beneficiaries 1999–2014
Goldsweig AM, Wang Y, Forrest JK, Cleman MW, Minges KE, Mangi AA, Aronow HD, Krumholz HM, Curtis JP. Ventricular septal rupture complicating acute myocardial infarction: Incidence, treatment, and outcomes among medicare beneficiaries 1999–2014. Catheterization And Cardiovascular Interventions 2018, 92: 1104-1115. PMID: 29513365, DOI: 10.1002/ccd.27576.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionVentricular septal ruptureTimely primary PCIMortality ratePrimary PCIPercutaneous repairSeptal ruptureMyocardial infarctionRetrospective cohort studyUnadjusted mortality ratesUnrepaired patientsVSR repairFatal complicationCohort studyAnnual incidenceMedicare feeService beneficiariesPatientsIncidenceStudy periodMortalityHospitalizationInfarctionRepairPCIAdoption of the transradial approach for percutaneous coronary intervention and rates of vascular complications following transfemoral procedures: Insights from NCDR
Badri M, Shapiro T, Wang Y, Minges KE, Curtis JP, Gray WA. Adoption of the transradial approach for percutaneous coronary intervention and rates of vascular complications following transfemoral procedures: Insights from NCDR. Catheterization And Cardiovascular Interventions 2018, 92: 835-841. PMID: 29359497, DOI: 10.1002/ccd.27490.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionTransfemoral percutaneous coronary interventionVascular complicationsTransradial approachCoronary interventionAccess site bleedingNCDR CathPCI RegistryFemoral operatorsTransfemoral proceduresRetroperitoneal bleedingCathPCI RegistrySite bleedingRetrospective analysisComplicationsPropensity scorePreadoption periodBleedingMeaningful increaseInterventionRecent studiesHematomaRegistryNCDRAccess skillsPhysicians
2016
Vena Caval Filter Utilization and Outcomes in Pulmonary Embolism Medicare Hospitalizations From 1999 to 2010
Bikdeli B, Wang Y, Minges KE, Desai NR, Kim N, Desai MM, Spertus JA, Masoudi FA, Nallamothu BK, Goldhaber SZ, Krumholz HM. Vena Caval Filter Utilization and Outcomes in Pulmonary Embolism Medicare Hospitalizations From 1999 to 2010. Journal Of The American College Of Cardiology 2016, 67: 1027-1035. PMID: 26940921, PMCID: PMC5322943, DOI: 10.1016/j.jacc.2015.12.028.Peer-Reviewed Original Research
2015
Patterns of Institutional Review of Percutaneous Coronary Intervention Appropriateness and the Effect on Quality of Care and Clinical Outcomes
Desai NR, Parzynski CS, Krumholz HM, Minges KE, Messenger JC, Nallamothu BK, Curtis JP. Patterns of Institutional Review of Percutaneous Coronary Intervention Appropriateness and the Effect on Quality of Care and Clinical Outcomes. JAMA Internal Medicine 2015, 175: 1988. PMID: 26551259, PMCID: PMC5584388, DOI: 10.1001/jamainternmed.2015.6217.Peer-Reviewed Original ResearchNational Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010)
Minges KE, Bikdeli B, Wang Y, Kim N, Curtis JP, Desai MM, Krumholz HM. National Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010). The American Journal Of Cardiology 2015, 116: 1436-1442. PMID: 26409636, PMCID: PMC4841688, DOI: 10.1016/j.amjcard.2015.07.068.Peer-Reviewed Original ResearchConceptsHospitalization ratesMortality rateReadmission ratesBlack patientsPrincipal discharge diagnosis codeOlder adultsCause readmission rateHospital mortality rateProportion of patientsRetrospective cohort studyDischarge diagnosis codesSkilled nursing facilitiesNational trendsSignificant racial differencesHigh rateHome health careHospital stayAdults AgedCohort studyMore patientsTherapeutic advancesDiagnosis codesMedicare feeNursing facilitiesSignificant burden
2014
National Trends in US Hospital Admissions for Hyperglycemia and Hypoglycemia Among Medicare Beneficiaries, 1999 to 2011
Lipska KJ, Ross JS, Wang Y, Inzucchi SE, Minges K, Karter AJ, Huang ES, Desai MM, Gill TM, Krumholz HM. National Trends in US Hospital Admissions for Hyperglycemia and Hypoglycemia Among Medicare Beneficiaries, 1999 to 2011. JAMA Internal Medicine 2014, 174: 1116-1124. PMID: 24838229, PMCID: PMC4152370, DOI: 10.1001/jamainternmed.2014.1824.Peer-Reviewed Original Research
2011
Evaluation of a resistance training program for adults with or at risk of developing diabetes: an effectiveness study in a community setting
Minges KE, Cormick G, Unglik E, Dunstan DW. Evaluation of a resistance training program for adults with or at risk of developing diabetes: an effectiveness study in a community setting. International Journal Of Behavioral Nutrition And Physical Activity 2011, 8: 50. PMID: 21612648, PMCID: PMC3127967, DOI: 10.1186/1479-5868-8-50.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAustraliaBody CompositionCross-Sectional StudiesData CollectionDiabetes Mellitus, Type 2Evidence-Based PracticeFemaleFollow-Up StudiesHealth PromotionHumansLongitudinal StudiesMaleMiddle AgedMotor ActivityObesityRegression AnalysisResistance TrainingRetrospective StudiesTime FactorsWaist CircumferenceConceptsResistance training programType 2 diabetesWaist circumferenceUpper body strengthFunctional measuresBody strengthLower bodyMean waist circumferenceSignificant time effectTraining programCentral obesityPhysical functionWeek assessmentFavorable health benefitsDiabetesEffectiveness studiesStudy designConclusionsThese findingsRetrospective assessmentBaselineHealth benefitsCircumferenceSignificant decreaseLongitudinal studyFitness facilities