2020
Comparison of left ventricular lead upgrade vs continued medical care among patients eligible for cardiac resynchronization therapy at the time of defibrillator generator replacement: Predictors of left ventricular lead upgrade and associations with long-term outcomes
Hyman MC, Bao H, Curtis JP, Minges K, Schaller RD, Birgersdotter-Green U, Marchlinski FE, Hsu JC. Comparison of left ventricular lead upgrade vs continued medical care among patients eligible for cardiac resynchronization therapy at the time of defibrillator generator replacement: Predictors of left ventricular lead upgrade and associations with long-term outcomes. Heart Rhythm 2020, 17: 1878-1886. PMID: 32497762, DOI: 10.1016/j.hrthm.2020.05.032.Peer-Reviewed Original ResearchConceptsCardiac resynchronization therapyCRT-eligible patientsCRT upgradeResynchronization therapyClinical outcomesNational Cardiovascular Data Registry ICD RegistryGenerator replacementPeriprocedural complication rateLeft ventricular leadSubpopulation of patientsLong-term outcomesICD generator replacementHierarchical logistic regression modelsLogistic regression modelsSecondary endpointsCause mortalityPrimary endpointComplication rateICD RegistryProcedural complicationsMedical managementICD populationNational registryVentricular leadClaims data
2019
Use of Cardiac Resynchronization Therapy Defibrillator in US Hospitals
Sandhu A, Bao H, Minges KE, Varosy PD, Borne RT, Zipse MM, Marzec L, Peterson P, Masoudi F, Bradley SM. Use of Cardiac Resynchronization Therapy Defibrillator in US Hospitals. JAMA Cardiology 2019, 4: 804-809. PMID: 31215970, PMCID: PMC6584888, DOI: 10.1001/jamacardio.2019.1755.Peer-Reviewed Original ResearchConceptsCRT-D implantationCardiac resynchronization therapyNonspecific intraventricular conduction delayIntraventricular conduction delayBundle branch blockGuideline updateConduction abnormalitiesBranch blockConduction delayAmerican CollegeNon-left bundle branch blockLeft ventricular systolic dysfunctionCardiac resynchronization therapy defibrillatorNational Cardiovascular Data RegistryRight bundle branch blockCRT-D implantVentricular systolic dysfunctionPopulation-based studyDevice-based therapiesMinority of hospitalsSystolic dysfunctionCRT-defibrillatorElectrocardiographic evidenceSelect patientsResynchronization therapyCardiac Resynchronization Defibrillator Therapy for Nonspecific Intraventricular Conduction Delay Versus Right Bundle Branch Block
Kawata H, Bao H, Curtis JP, Minges KE, Mitiku T, Birgersdotter-Green U, Feld GK, Hsu JC. Cardiac Resynchronization Defibrillator Therapy for Nonspecific Intraventricular Conduction Delay Versus Right Bundle Branch Block. Journal Of The American College Of Cardiology 2019, 73: 3082-3099. PMID: 31221257, DOI: 10.1016/j.jacc.2019.04.025.Peer-Reviewed Original ResearchConceptsNonspecific intraventricular conduction delayRight bundle branch blockCardiac resynchronization therapyCRT-D implantationCRT-eligible patientsBundle branch blockQRS durationHazard ratioBranch blockBetter outcomesCardiac resynchronization defibrillator therapyMultivariable adjusted hazard ratiosAdjusted hazard ratioIntraventricular conduction delayCareful patient selectionEligible patientsDefibrillator therapyMultivariable adjustmentResynchronization therapyClinical outcomesPatient selectionConduction abnormalitiesRegistry dataConduction delayPatients