2013
Clinical Presentation in Diffuse Low-Grade Gliomas
Torres-Reveron J, Piepmeier J, Becker K. Clinical Presentation in Diffuse Low-Grade Gliomas. 2013, 179-188. DOI: 10.1007/978-1-4471-2213-5_12.Peer-Reviewed Original ResearchDiffuse low-grade gliomasLow-grade gliomasCommon presenting symptomHigh-grade lesionsPrimary brain tumorsStandard imaging modalityPresenting symptomHistopathological findingsClinical presentationTumor sizeNeurological syndromeAnaplastic transformationBrain tumorsMultimodal evaluationConventional imaging technologiesImaging modalitiesActive investigationTumorsGliomasNew advancesSeizuresSyndromeLesionsSymptoms
2012
Low-Grade Gliomas When and How to Treat
Omay SB, Piepmeier JM, Knisely JP. Low-Grade Gliomas When and How to Treat. Hematology/Oncology Clinics Of North America 2012, 26: 797-809. PMID: 22794284, DOI: 10.1016/j.hoc.2012.05.001.Peer-Reviewed Original ResearchConceptsSurgical resectionLow-grade gliomasPatient-specific variablesSame imaging techniqueRadiotherapeutic managementUncommon tumorClinical trialsOperative techniqueHistopathologic characterizationGrade gliomasOptimal managementAdditional studiesGliomasResectionAdequate samplesImaging techniquesPatientsPrognosisManagementTumorsTrials
2006
The Interactions of Polarographic Measurements of Oxygen Tension and Histological Grade in Human Glioma
Lally BE, Rockwell S, Fischer DB, Collingridge DR, Piepmeier JM, Knisely JP. The Interactions of Polarographic Measurements of Oxygen Tension and Histological Grade in Human Glioma. The Cancer Journal 2006, 12: 461-466. PMID: 17207315, DOI: 10.1097/00130404-200611000-00005.Peer-Reviewed Original ResearchConceptsHistological gradeHigh-grade gliomasLow-grade gliomasTumor oxygen tensionUnivariate analysisOxygen tensionGrade gliomasSignificant independent prognostic indicatorExtent of surgeryType of anesthesiaIndependent prognostic indicatorEppendorf pO2 histographTissue oxygen tensionNormal brain tissueImplications of hypoxiaOverall survivalProspective trialPatient ageEntire cohortPrognostic indicatorPatient genderPoor survivalMedian pO2PatientsPO2 histograph
2005
Novel Tumor-Specific Isoforms of BEHAB/Brevican Identified in Human Malignant Gliomas
Viapiano MS, Bi WL, Piepmeier J, Hockfield S, Matthews RT. Novel Tumor-Specific Isoforms of BEHAB/Brevican Identified in Human Malignant Gliomas. Cancer Research 2005, 65: 6726-6733. PMID: 16061654, DOI: 10.1158/0008-5472.can-05-0585.Peer-Reviewed Original ResearchConceptsBEHAB/brevicanHigh-grade gliomasMalignant gliomasBrain tumorsNew potential therapeutic targetsPrimary brain tumorsNormal adult brainDeadly brain tumorCentral nervous systemPotential therapeutic targetLow-grade gliomasHuman malignant gliomasNew therapeutic strategiesPathologic courseSimilar histologyBenign gliomasAdult brainTherapeutic strategiesDiffuse invasionTherapeutic targetGlioma progressionNervous systemInvasive abilityBrain tissueGliomas
2004
Surgical Resection for Patients with Benign Primary Brain Tumors and Low Grade Gliomas
Piepmeier J, Baehring JM. Surgical Resection for Patients with Benign Primary Brain Tumors and Low Grade Gliomas. Journal Of Neuro-Oncology 2004, 69: 55-65. PMID: 15527080, DOI: 10.1023/b:neon.0000041871.46785.53.Peer-Reviewed Original ResearchConceptsPrimary brain tumorsBrain tumorsNeuroepithelial tumorsBenign primary brain tumorsMajority of patientsAdverse treatment effectsBenefits of therapyLow-grade tumorsLow-grade gliomasSurgical resectionInitial diagnosisMalignant degenerationPrimary neoplasmsSurgical managementSeizure focusBrain parenchymaChordoid gliomaNeurosurgical interventionThird ventricleChoroid plexusGrade gliomasTumorsUnknown originHeterogeneous groupCell pool
1999
Complications and Expected Outcome of Glioma Surgery
Vives K, Piepmeier J. Complications and Expected Outcome of Glioma Surgery. Journal Of Neuro-Oncology 1999, 42: 289-302. PMID: 10433111, DOI: 10.1023/a:1006163328765.Peer-Reviewed Original ResearchConceptsSurgical resectionKarnofsky performance statusGross total resectionManagement of patientsRisk of complicationsUse of radiotherapyRisk of recurrenceHigh-grade lesionsMaximum safe resectionCareful preoperative planningHigh-grade gliomasLow-grade gliomasPerformance statusExtensive surgeryMajor complicationsProlong survivalTotal resectionNeurologic impairmentGrade lesionsSafe resectionTreatment modalitiesIntraoperative mappingGlioma surgeryIntracerebral gliomasSurvival advantage
1997
Low-grade gliomas of chronic epilepsy: A distinct clinical and pathological entity
Bartolomei J, Christopher S, Vives K, Spencer D, Piepmeier J. Low-grade gliomas of chronic epilepsy: A distinct clinical and pathological entity. Journal Of Neuro-Oncology 1997, 34: 79-84. PMID: 9210054, DOI: 10.1023/a:1005711321343.Peer-Reviewed Original ResearchConceptsLow-grade gliomasChronic epilepsyDysembryoplastic neuroepithelial tumorPathological entityLong-term patient outcomesSpecific pathological entityManagement of patientsResults of patientsDistinct pathological entityLack of mortalityPreoperative seizuresNeuroepithelial tumorsTumor recurrencePatient outcomesAnaplastic transformationEpilepsySame tumorGliomasCortical locationTumorsPatientsRecurrenceSeizuresPopulationMortality