1997
Vascular endothelial growth factor mediates reactive angiogenesis in the postnatal developing brain
Ment L, Stewart W, Fronc R, Seashore C, Mahooti S, Scaramuzzino D, Madri J. Vascular endothelial growth factor mediates reactive angiogenesis in the postnatal developing brain. Brain Research 1997, 100: 52-61. PMID: 9174246, DOI: 10.1016/s0165-3806(97)00012-6.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornAstrocytesCell DivisionCell HypoxiaCells, CulturedCerebral CortexCoculture TechniquesEndothelial Growth FactorsEndothelium, VascularHypoxia, BrainLymphokinesMicrocirculationNeovascularization, PathologicNeovascularization, PhysiologicRatsRats, Sprague-DawleyRNA, MessengerTranscription, GeneticVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsConceptsVascular endothelial growth factorEndothelial growth factorVEGF protein levelsExperimental ratsSublethal hypoxiaBrain microvascular endothelial cellsEndothelial cellsGrowth factorChronic sublethal hypoxiaProtein levelsAge-matched controlsMicrovascular endothelial cellsHypoxic pupsHRP studyCortical vesselsImmunohistochemical studyVascular densityAddition of VEGFBeagle pupsNewborn ratsReactive angiogenesisAstrocyte culturesThree-dimensional cocultureRat forebrainVEGF protein
1992
Indomethacin promotes germinal matrix microvessel maturation in the newborn beagle pup.
Ment L, Stewart W, Ardito T, Huang E, Madri J. Indomethacin promotes germinal matrix microvessel maturation in the newborn beagle pup. Stroke 1992, 23: 1132-1137. PMID: 1636188, DOI: 10.1161/01.str.23.8.1132.Peer-Reviewed Original ResearchConceptsNewborn beagle pupsPostnatal day 2Germinal matrixPostnatal ageBeagle pupsIntraventricular hemorrhageVessel densityDay 2Postnatal day 1Laminin depositionMechanism of actionMicrovessel maturationStudy medicationBeta 1 integrinImmunohistochemical studyPostnatal dayDose i.Animal studiesDay 1IndomethacinNewborn pupsHemorrhageBasement membrane depositionBuffered formalinCollagen staining
1991
Beagle pup germinal matrix maturation studies.
Ment L, Stewart W, Ardito T, Madri J. Beagle pup germinal matrix maturation studies. Stroke 1991, 22: 390-395. PMID: 2003309, DOI: 10.1161/01.str.22.3.390.Peer-Reviewed Original ResearchConceptsAlpha-smooth muscle actinIntraventricular hemorrhageDay 1Muscle actinRisk periodGlial fibrillary acidic proteinGerminal matrix vasculatureNewborn beagle pupsPostnatal day 1Postnatal day 4Postnatal day 10Fibrillary acidic proteinGerminal matrix vesselsGerminal matrix tissuePreterm infantsImmunohistochemical studyPerinatal maturationPostnatal dayBeagle pupsVessel densityHemorrhageExtracellular matrix componentsDay 4Day 10Basement membrane proteins
1982
An immunohistochemical study of adenomatoid tumors utilizing keratin and factor VIII antibodies. Evidence for a mesothelial origin.
Barwick K, Madri J. An immunohistochemical study of adenomatoid tumors utilizing keratin and factor VIII antibodies. Evidence for a mesothelial origin. Laboratory Investigation 1982, 47: 276-80. PMID: 6180248.Peer-Reviewed Original ResearchConceptsAdenomatoid tumorMesothelial originAntigen antibodiesKeratin antibodiesFactor VIII antibodiesImmunohistochemical studyAdenoid cellsVIII antibodiesAdenoid structuresEndothelial originFactor VIIIParaffin blocksTumorsCases tissueAntibodiesHistochemical dataAntibody probesImmunoelectron microscopyAdditional evidenceCellsAntigenKeratinAn immunohistochemical study of nasopharyngeal neoplasms using keratin antibodies
Madri J, Barwick K. An immunohistochemical study of nasopharyngeal neoplasms using keratin antibodies. The American Journal Of Surgical Pathology 1982, 6: 143-150. PMID: 6179429, DOI: 10.1097/00000478-198203000-00006.Peer-Reviewed Original ResearchConceptsKeratin antibodiesNasopharyngeal neoplasmsSquamous cell carcinomaUsual staining methodsCell carcinomaMesenchymal tumorsImmunohistochemical studyImmunohistochemical meansAccurate diagnosisAntibodiesNeoplasmsTumorsStaining methodKeratin proteinsNonkeratinizingCarcinomaNasopharynxNeoplasiaSensitive methodDiagnosis