2024
The role of anatomic shape features in the prognosis of uncomplicated type B aortic dissection initially treated with optimal medical therapy
Liu M, Dong H, Mazlout A, Wu Y, Kalyanasundaram A, Oshinski J, Sun W, Elefteriades J, Leshnower B, Gleason R. The role of anatomic shape features in the prognosis of uncomplicated type B aortic dissection initially treated with optimal medical therapy. Computers In Biology And Medicine 2024, 170: 108041. PMID: 38330820, PMCID: PMC10932856, DOI: 10.1016/j.compbiomed.2024.108041.Peer-Reviewed Original ResearchConceptsType B aortic dissectionTreated with optimal medical therapyAortic growth rateOptimal medical therapyUncomplicated type B aortic dissectionB aortic dissectionMedical therapyCT scanPatients' long-term survivalType B aortic dissection patientsLong-term outcomesLong-term survivalFailure groupAortic expansionChronic phaseFailure patientsPatientsCT imagesTherapyDissectionStatistical shape modelFailurePrognosisScanningRegression
2023
Aortic Size at the Time of Type A and Type B Dissections
Perez Z, Zafar M, Velasco J, Sonsino A, Ellauzi H, John C, Kalyanasundaram A, Ziganshin B, Elefteriades J. Aortic Size at the Time of Type A and Type B Dissections. The Annals Of Thoracic Surgery 2023, 116: 262-268. PMID: 37062339, DOI: 10.1016/j.athoracsur.2023.03.037.Peer-Reviewed Original ResearchMeSH KeywordsAortaAortic Aneurysm, ThoracicAortic DissectionBicuspid Aortic Valve DiseaseFemaleHumansMaleRisk FactorsConceptsType B dissectionTime of dissectionB dissectionAortic sizeAortic diameterBicuspid aortic valveThoracic aortic aneurysmAortic interventionAortic dissectionSurgical interventionAortic aneurysmFemale sexAortic valveThoracic aortaProphylactic repairUnadjusted regressionLeft shiftLogistic regressionDissectionNew guidelinesType ASize criteriaOddsInterventionTime of typesFate of the unoperated ascending thoracic aortic aneurysm: three-decade experience from the Aortic Institute at Yale University
Wu J, Zafar M, Liu Y, Chen J, Li Y, Ziganshin B, Ellauzi H, Mukherjee S, Rizzo J, Elefteriades J. Fate of the unoperated ascending thoracic aortic aneurysm: three-decade experience from the Aortic Institute at Yale University. European Heart Journal 2023, 44: 4579-4588. PMID: 36994934, DOI: 10.1093/eurheartj/ehad148.Peer-Reviewed Original ResearchConceptsAdverse aortic eventsThoracic aortic aneurysmAortic sizeAortic aneurysmCox regressionAortic growthRisk factorsSignificant independent risk factorsMultivariable Cox regressionIndependent risk factorCohort of patientsUnivariable Cox regressionSignificant protective factorAortic deathATAA patientsAortic eventsPrimary endpointSurgical interventionThree-decade experienceNatural historyYearly riskProtective factorsAneurysmsPatientsIntervention criteria
2016
Neurological Events Following Transcatheter Aortic Valve Replacement and Their Predictors
Kleiman N, Maini B, Reardon M, Conte J, Katz S, Rajagopal V, Kauten J, Hartman A, McKay R, Hagberg R, Huang J, Popma J, Adams D, Ad N, Aharonian V, Anderson W, Applegate R, Bafi A, Bajwa T, Bakhos M, Ball S, Batra S, Beohar N, Brachinsky W, Brinster D, Brown J, Byrne J, Byrne T, Casale A, Caskey M, Chawla A, Cohen H, Coselli J, Costa M, Cheatham J, Chetcuti S, Crestanello J, Davis T, Michael Deeb G, Diez J, Dauerman H, Elefteriades J, Fail P, Feinberg E, Fontana G, Forrest J, Galloway A, Giacomini J, Gleason T, Guadiani V, Harrison J, Hebeler R, Heimansohn D, Heiser J, Heller L, Henry S, Hermiller J, Hockmuth D, Hughes G, Joye J, Kafi A, Kar B, Khabbaz K, Kipperman R, Kliger C, Kon N, Lamelas J, Lee J, Leya F, Londono J, Macheers S, Mangi A, de Marchena E, Markowitz A, Matthews R, Merhi W, Mumtaz M, O’Hair D, Petrossian G, Pfeffer T, Raybuck B, Resar J, Robbins M, Robbins R, Robinson N, Ring M, Salerno T, Schreiber T, Schmoker J, Sharma S, Siwek L, Skelding K, Slater J, Starnes V, Stoler R, Subramanian V, Tadros P, Thompson C, Waksman R, Watson D, Yakubov S, Zhao D, Zorn G. Neurological Events Following Transcatheter Aortic Valve Replacement and Their Predictors. Circulation Cardiovascular Interventions 2016, 9: e003551. PMID: 27601429, DOI: 10.1161/circinterventions.115.003551.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisBalloon ValvuloplastyBioprosthesisCalcinosisCardiac Pacing, ArtificialClinical Trials as TopicFemaleHeart Valve ProsthesisHumansIncidenceIntracranial EmbolismKaplan-Meier EstimateMaleProportional Hazards ModelsRisk AssessmentRisk FactorsSeverity of Illness IndexStrokeTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsTranscatheter aortic valve replacementAortic valve replacementValve replacementEarly strokePrior coronary artery bypass surgeryHealth Stroke Scale scoreSelf-expanding CoreValve bioprosthesisCoronary artery bypass surgerySmaller body surface areaLower body mass indexContinued Access StudySevere aortic calcificationStroke Scale scoreTransient ischemic attackArtery bypass surgeryPeripheral vascular diseasePredictors of strokeBody mass indexBody surface areaIdentification of predictorsCoreValve bioprosthesisIschemic attackPrior strokeBypass surgeryAortic calcification
2001
Stroke in surgery of the thoracic aorta: Incidence, impact, etiology, and prevention
Goldstein L, Davies R, Rizzo J, Davila J, Cooperberg M, Shaw R, Kopf G, Elefteriades J. Stroke in surgery of the thoracic aorta: Incidence, impact, etiology, and prevention. Journal Of Thoracic And Cardiovascular Surgery 2001, 122: 935-945. PMID: 11689799, DOI: 10.1067/mtc.2001.117276.Peer-Reviewed Original ResearchConceptsDeep hypothermic circulatory arrestHypothermic circulatory arrestThoracic aortaCirculatory arrestEmergency operationAge-adjusted survivalAntegrade cerebral perfusionThoracic aortic operationsPrevention of strokeIntensive care unitPostoperative stayAortic atheromaAortic manipulationAortic operationsPostoperative deathsCardiopulmonary bypassCerebral perfusionFemoral perfusionNeurologic consultationCare unitElective operationsHeart bypassThorough debridementOperative reportsLeft heart
1999
NATURAL HISTORY, PATHOGENESIS, AND ETIOLOGY OF THORACIC AORTIC ANEURYSMS AND DISSECTIONS
Coady M, Rizzo J, Goldstein L, Elefteriades J. NATURAL HISTORY, PATHOGENESIS, AND ETIOLOGY OF THORACIC AORTIC ANEURYSMS AND DISSECTIONS. Cardiology Clinics 1999, 17: 615-635. PMID: 10589336, DOI: 10.1016/s0733-8651(05)70105-3.Peer-Reviewed Original ResearchINTERPRETING DATA ON THORACIC AORTIC ANEURYSMS Statistical Issues
Rizzo J, Coady M, Elefteriades J. INTERPRETING DATA ON THORACIC AORTIC ANEURYSMS Statistical Issues. Cardiology Clinics 1999, 17: 797-805. PMID: 10589346, DOI: 10.1016/s0733-8651(05)70115-6.Peer-Reviewed Original Research
1998
Procedures for Estimating Growth Rates in Thoracic Aortic Aneurysms
Rizzo J, Coady M, Elefteriades J. Procedures for Estimating Growth Rates in Thoracic Aortic Aneurysms. Journal Of Clinical Epidemiology 1998, 51: 747-754. PMID: 9731923, DOI: 10.1016/s0895-4356(98)00050-x.Peer-Reviewed Original ResearchConceptsTAA growth ratesStatistical problemsStatistical methodsEstimation procedureTAA growthConventional approachesMore reliable resultsInstrumental variable estimationVariable estimationMeasurement errorRate estimatesPrecise estimatesEstimationMeasured growth rateReliable estimatesEstimatesReliable resultsProblemConventional methodsApproachLethal medical conditionError
1997
What is the appropriate size criterion for resection of thoracic aortic aneurysms?
Coady M, Rizzo J, Hammond G, Mandapati D, Darr U, Kopf G, Elefteriades J. What is the appropriate size criterion for resection of thoracic aortic aneurysms? Journal Of Thoracic And Cardiovascular Surgery 1997, 113: 476-491. PMID: 9081092, DOI: 10.1016/s0022-5223(97)70360-x.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmAortic aneurysmIncidence of dissectionTime of complicationsMultivariable regression analysisMedian sizeAppropriate size criterionTime of dissectionAcute dissectionElective resectionPerioperative complicationsDevastating complicationOverall survivalAortic dissectionInitial presentationElective operationsSurgical interventionRisk factorsThoracic aortaAneurysm sizeTime of rupturePatientsYale University SchoolAneurysmsLower mortality
1995
Valve Replacement for Regurgitant Lesions of the Aortic or Mitral Valve in Advanced Left Ventricular Dysfunction
Bonow R, Nikas D, Elefteriades J. Valve Replacement for Regurgitant Lesions of the Aortic or Mitral Valve in Advanced Left Ventricular Dysfunction. Cardiology Clinics 1995, 13: 73-83. PMID: 7796434, DOI: 10.1016/s0733-8651(18)30063-8.Peer-Reviewed Original ResearchConceptsLeft ventricular dysfunctionAdvanced left ventricular dysfunctionSevere left ventricular dysfunctionVentricular dysfunctionValve replacementLate left ventricular dysfunctionSubvalvular mitral apparatusSevere systolic dysfunctionAortic valve replacementCongestive heart failureMitral valve repairRegurgitant valvular lesionsSystolic dysfunctionAortic regurgitationSystolic functionHeart failureValvular lesionsCardiology clinicMitral regurgitationValve repairSevere depressionMitral valveMitral apparatusPatient's familyAlternative treatment