2024
Protective Biomechanical and Histological Changes in the False Lumen Wall in Chronic Type B Aortic Dissection
Dong H, Liu M, Cebull H, Chhabra A, Zhou Y, Piccinelli M, Oshinski J, Elefteriades J, Gleason R, Leshnower B. Protective Biomechanical and Histological Changes in the False Lumen Wall in Chronic Type B Aortic Dissection. JTCVS Open 2024 DOI: 10.1016/j.xjon.2024.11.012.Peer-Reviewed Original ResearchChronic phaseChronic type B aortic dissectionType B aortic dissectionHistological changesB aortic dissectionIncreased aortic stiffnessAcute to chronic phaseAortic stiffnessDecreased elastinIncreased collagenQuantification of collagenBiaxial tension testsStress-strain curvesBiomechanical stiffnessTension testsAssess stiffnessHuman tissuesCollagenThe use of 4-dimensional flow magnetic resonance imaging and fluid structure interaction analysis to predict failure of medical therapy in acute uncomplicated type B aortic dissection
Cebull H, Liu M, Piccinelli M, Dong H, Naeem M, Du Y, Oshinski J, Gleason R, Elefteriades J, Leshnower B. The use of 4-dimensional flow magnetic resonance imaging and fluid structure interaction analysis to predict failure of medical therapy in acute uncomplicated type B aortic dissection. JTCVS Techniques 2024, 27: 40-44. PMID: 39478892, PMCID: PMC11519730, DOI: 10.1016/j.xjtc.2024.06.019.Peer-Reviewed Original Research4D Flow MRI-Derived Hemodynamic Parameters Related to Growth in Acute Type B Aortic Dissections
Cebull H, Liu M, Dong H, Elefteriades J, Gleason R, Piccinelli M, Oshinski J, Leshnower B. 4D Flow MRI-Derived Hemodynamic Parameters Related to Growth in Acute Type B Aortic Dissections. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2024 DOI: 10.58530/2024/4770.Peer-Reviewed Original ResearchType B aortic dissectionAcute type B aortic dissectionB aortic dissectionAortic growthHigh-risk patientsPreemptive treatmentSurgical outcomesTBAD patientsIn vivo hemodynamicsStratify riskHemodynamic parametersImprove outcomesHemodynamic markersAcute patientsPatientsDissectionFlow MRIHemodynamic metricsTearsMRI dataOutcomesThe role of anatomic shape features in the prognosis of uncomplicated type B aortic dissection initially treated with optimal medical therapy
Liu M, Dong H, Mazlout A, Wu Y, Kalyanasundaram A, Oshinski J, Sun W, Elefteriades J, Leshnower B, Gleason R. The role of anatomic shape features in the prognosis of uncomplicated type B aortic dissection initially treated with optimal medical therapy. Computers In Biology And Medicine 2024, 170: 108041. PMID: 38330820, PMCID: PMC10932856, DOI: 10.1016/j.compbiomed.2024.108041.Peer-Reviewed Original ResearchConceptsType B aortic dissectionTreated with optimal medical therapyAortic growth rateOptimal medical therapyUncomplicated type B aortic dissectionB aortic dissectionMedical therapyCT scanPatients' long-term survivalType B aortic dissection patientsLong-term outcomesLong-term survivalFailure groupAortic expansionChronic phaseFailure patientsPatientsCT imagesTherapyDissectionStatistical shape modelFailurePrognosisScanningRegression
2021
Acute Type B Aortic Dissection: Clinical Perspectives to Guide Surgery
Elefteriades J, Ziganshin B. Acute Type B Aortic Dissection: Clinical Perspectives to Guide Surgery. 2021, 227-232. DOI: 10.1007/978-3-030-78877-3_63.Peer-Reviewed Original Research
1999
PATHOLOGIC VARIANTS OF THORACIC AORTIC DISSECTIONS Penetrating Atherosclerotic Ulcers and Intramural Hematomas
Coady M, Rizzo J, Elefteriades J. PATHOLOGIC VARIANTS OF THORACIC AORTIC DISSECTIONS Penetrating Atherosclerotic Ulcers and Intramural Hematomas. Cardiology Clinics 1999, 17: 637-657. PMID: 10589337, DOI: 10.1016/s0733-8651(05)70106-5.Peer-Reviewed Original ResearchConceptsClassic aortic dissectionAcute aortic pathologyIntramural hematomaAortic dissectionAortic lumenAtherosclerotic ulcerAortic lesionsIMH patientsAortic pathologyClassic dissectionRupture rateType B aortic dissectionTypical aortic dissectionB aortic dissectionDistinct clinical entityThoracic aortic dissectionTypical patient profileMore superficial locationHigher rupture rateBranch-vessel compromiseLarger aortasMinimal arteriosclerosisTypical dissectionIschemic manifestationsThoracoabdominal aorta
1998
Penetrating ulcer of the thoracic aorta: What is it? How do we recognize it? How do we manage it?
Coady M, Rizzo J, Hammond G, Pierce J, Kopf G, Elefteriades J. Penetrating ulcer of the thoracic aorta: What is it? How do we recognize it? How do we manage it? Journal Of Vascular Surgery 1998, 27: 1006-1016. PMID: 9652462, DOI: 10.1016/s0741-5214(98)70003-5.Peer-Reviewed Original ResearchConceptsAortic dissectionOptimal treatmentThoracic aortaNatural historyType AType B aortic dissectionB aortic dissectionClassic aortic dissectionLarger aortic diametersAortic ulcerAtherosclerotic ulcerAortic ruptureClinical featuresInitial diagnosisInitial presentationIntraoperative findingsRetrospective reviewSurgical managementAortic diameterRadiologic signsTomographic scanPathology reportsUlcersPatientsAorta