FGF-dependent metabolic control of vascular development
Yu P, Wilhelm K, Dubrac A, Tung JK, Alves TC, Fang JS, Xie Y, Zhu J, Chen Z, De Smet F, Zhang J, Jin SW, Sun L, Sun H, Kibbey RG, Hirschi KK, Hay N, Carmeliet P, Chittenden TW, Eichmann A, Potente M, Simons M. FGF-dependent metabolic control of vascular development. Nature 2017, 545: 224-228. PMID: 28467822, PMCID: PMC5427179, DOI: 10.1038/nature22322.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell MovementCell ProliferationEndothelial CellsFemaleFibroblast Growth FactorsGlycolysisHexokinaseLymphangiogenesisLymphatic VesselsMiceMice, Inbred C57BLNeovascularization, PhysiologicProto-Oncogene Proteins c-mycReceptor, Fibroblast Growth Factor, Type 1Receptor, Fibroblast Growth Factor, Type 3Signal TransductionConceptsVascular developmentFibroblast growth factor receptor signalingGrowth factor receptor signalingCrucial regulatorReceptor signalingEndothelial metabolismSignalingRegulator