2023
Profilin1 is required to prevent mitotic catastrophe in murine and human glomerular diseases
Tian X, Pedigo C, Li K, Ma X, Bunda P, Pell J, Lek A, Gu J, Zhang Y, Rangel P, Li W, Schwartze E, Nagata S, Lerner G, Perincheri S, Priyadarshini A, Zhao H, Lek M, Menon M, Fu R, Ishibe S. Profilin1 is required to prevent mitotic catastrophe in murine and human glomerular diseases. Journal Of Clinical Investigation 2023, 133: e171237. PMID: 37847555, PMCID: PMC10721156, DOI: 10.1172/jci171237.Peer-Reviewed Original ResearchConceptsProteinuric kidney diseaseKidney diseasePodocyte lossHuman glomerular diseasesMitotic catastrophePodocyte cell cycleSevere proteinuriaCell cycle reentryKidney failureGlomerular diseaseCell cycleKidney tissueG1/S checkpointUnsuccessful repairCyclin D1Glomerular integrityIrregular nucleiTissue-specific lossMouse podocytesPodocytesAltered expressionDiseaseCyclin B1Ribosome affinity purificationMultinucleated cells
2022
Short-Term Effects of Ambient Air Pollutants on Outpatient Visits for Childhood Allergic Diseases in Shanghai, China
Hu Y, Gu J, Wu D, Wang X, Lü H, Yu G. Short-Term Effects of Ambient Air Pollutants on Outpatient Visits for Childhood Allergic Diseases in Shanghai, China. Journal Of Shanghai Jiaotong University (Science) 2022, 29: 979-994. DOI: 10.1007/s12204-022-2454-1.Peer-Reviewed Original ResearchChildhood allergic diseasesAmbient air pollutantsAllergic diseasesOutpatient visitsShort-term exposureTotal outpatient visitsAtopic dermatitisLag non-linear modelAge stratificationShort-term effectsDiseaseVisitsPositive associationTerm effectsAir pollutantsDisease classificationExposureAsthmaDermatitis
2016
Gut microbiota community adaption during young children fecal microbiota transplantation by 16s rDNA sequencing
Gu J, Wang Y, Liu S, Yu G, Zhang T, Lu H. Gut microbiota community adaption during young children fecal microbiota transplantation by 16s rDNA sequencing. Neurocomputing 2016, 206: 66-72. DOI: 10.1016/j.neucom.2016.01.095.Peer-Reviewed Original ResearchFecal microbiota transplantationMicrobiota transplantationGastrointestinal disordersGastrointestinal diseasesChronic gastrointestinal diseasePediatric gastrointestinal disordersFecal microbiota compositionUseful treatment methodRDNA sequencing technologyAdult patientsFMT treatmentYounger patientsFecal transplantationHealthy donorsIntestinal microbiotaMicrobiota compositionPatientsTransplantationInterindividual variabilityFecal microbiotaIntestinal environmentYoung childrenDiseased individualsDiseaseTreatment methods