2023
ABO-Incompatible Platelet Transfusion Is Associated with Ischemic Lesions on Brain MRI in Patients with Intracerebral Hemorrhage
Poyraz F, Ridha M, Simonetto M, Kumar A, Hess E, Magid-Bernstein J, Connolly E, Ghoshal S, Agarwal S, Park S, Claassen J, Hod E, Roh D. ABO-Incompatible Platelet Transfusion Is Associated with Ischemic Lesions on Brain MRI in Patients with Intracerebral Hemorrhage. Blood 2023, 142: 1288. DOI: 10.1182/blood-2023-186171.Peer-Reviewed Original ResearchABO-incompatible platelet transfusionsAcute ischemic brain lesionsIschemic brain lesionsIschemic lesionsPlatelet transfusionsICH patientsBrain MRIPlatelet unitsICH hospitalizationsICH severityBrain lesionsICH symptom onsetIncompatible platelet transfusionsProspective cohort studyAcute ischemic lesionsSpontaneous ICH patientsIntracerebral hemorrhage outcomesConsecutive spontaneous ICH patientsPatient's blood typeCerebral microthrombosisCohort studySymptom onsetRegression modelsClinical outcomesImpaired hemostasis
2022
Intraventricular Hemorrhage Expansion in the CLEAR III Trial: A Post Hoc Exploratory Analysis
Roh DJ, Asonye IS, Poyraz F, Magid-Bernstein JR, Joiner EF, Avadhani R, Awad I, Hanley DF, Ziai WC, Murthy SB. Intraventricular Hemorrhage Expansion in the CLEAR III Trial: A Post Hoc Exploratory Analysis. Stroke 2022, 53: 1847-1853. PMID: 35086362, PMCID: PMC9133068, DOI: 10.1161/strokeaha.121.037438.Peer-Reviewed Original ResearchConceptsCLEAR III trialVentriculoperitoneal shunt placementIntraventricular hemorrhage expansionIII trialsIVH patientsShunt placementICH locationHematoma expansionIVH expansionHemorrhage expansionSubsequent ventriculoperitoneal shunt placementGlasgow Coma Scale scoreBaseline ICH volumeClinical trial cohortComposite of deathLong-term outcomesMultivariable logistic regressionPoor functional outcomePost-hoc exploratory analysisMultivariable regression modelsIntracerebral hemorrhage volumeRandomization armAnticoagulant useTrial cohortClinical outcomes
2019
Low hemoglobin and hematoma expansion after intracerebral hemorrhage.
Roh DJ, Albers DJ, Magid-Bernstein J, Doyle K, Hod E, Eisenberger A, Murthy S, Witsch J, Park S, Agarwal S, Connolly ES, Elkind MSV, Claassen J. Low hemoglobin and hematoma expansion after intracerebral hemorrhage. Neurology 2019, 93: e372-e380. PMID: 31209179, PMCID: PMC6669932, DOI: 10.1212/wnl.0000000000007820.Peer-Reviewed Original ResearchConceptsAdmission hemoglobin levelsLower admission hemoglobin levelsLower hemoglobin levelsHemoglobin levelsHematoma expansionLower hemoglobinWorse outcomesMultivariable logistic regression modelSeparate multivariable logistic regression modelsPoor clinical outcomeMeeting inclusion criteriaIntracerebral hemorrhage volumeLogistic regression modelsAdmission hemoglobinRankin ScaleCohort studyConsecutive patientsClinical outcomesIntracerebral hemorrhagePoor outcomeICH outcomeICH scoreHemorrhage volumeModifiable targetsInclusion criteria