1977
Catecholamine receptors on locus coeruleus neurons: Pharmacological characterization
Cedarbaum J, Aghajanian G. Catecholamine receptors on locus coeruleus neurons: Pharmacological characterization. European Journal Of Pharmacology 1977, 44: 375-385. PMID: 330174, DOI: 10.1016/0014-2999(77)90312-0.Peer-Reviewed Original ResearchConceptsLC neuronsLocus coeruleusNoradrenergic neuronsCatecholamine receptorsΑ-receptorsCell bodiesΑ-methylnorepinephrinePostsynaptic α-receptorsPeripheral sympathetic nervesLocus coeruleus neuronsDopamine agonist apomorphineCentral dopamine receptorsΒ-agonist isoproterenolSingle-unit recordingsSympathetic nervesAgonist apomorphineAgonist clonidineMicroiontophoretic applicationCoeruleus neuronsSpontaneous firingΑ-adrenoreceptorsDopamine receptorsPharmacological characterizationAgonist drugsPharmacological characteristicsEffects of clonidine on habituation and sensitization of acoustic startle in normal, decerebrate and locus coeruleus lesioned rats
Davis M, Cedarbaum J, Aghajanian G, Gendelman D. Effects of clonidine on habituation and sensitization of acoustic startle in normal, decerebrate and locus coeruleus lesioned rats. Psychopharmacology 1977, 51: 243-253. PMID: 403539, DOI: 10.1007/bf00431631.Peer-Reviewed Original Research
1976
Noradrenergic neurons of the locus coeruleus: inhibition by epinephrine and activation by the α-antagonist piperoxane
Cedarbaum J, Aghajanian G. Noradrenergic neurons of the locus coeruleus: inhibition by epinephrine and activation by the α-antagonist piperoxane. Brain Research 1976, 112: 413-419. PMID: 8191, DOI: 10.1016/0006-8993(76)90297-3.Peer-Reviewed Original Research