2024
Association between fine particulate matter and eczema: A cross-sectional study of the All of Us Research Program and the Center for Air, Climate, and Energy Solutions.
Chen G, Hwang E, Leonard C, Cohen J. Association between fine particulate matter and eczema: A cross-sectional study of the All of Us Research Program and the Center for Air, Climate, and Energy Solutions. PLOS ONE 2024, 19: e0310498. PMID: 39536018, PMCID: PMC11560005, DOI: 10.1371/journal.pone.0310498.Peer-Reviewed Original ResearchConceptsPM2.5 concentrationsAmbient air pollutionUs Research ProgramAir pollutionCross-sectional studyAnnual PM2.5 concentrationCohort of American adultsPM2.5 exposureParticulate matterPM2.5Odds of eczemaPrevalence of eczemaAssociated with eczemaRisk of eczemaEnvironmental hazardsAtopic comorbiditiesPollutionSmoking statusTargeted interventionsZip codesAmerican adultsLogistic regressionAmerican cohortDemographic factorsOne-way analysis of varianceImpact of Atopic Dermatitis (Eczema) and Its Treatment on the Risk of Adverse Events Following Total Knee Arthroplasty
Smith-Voudouris J, Dhodapkar M, Halperin S, Cohen J, Grauer J. Impact of Atopic Dermatitis (Eczema) and Its Treatment on the Risk of Adverse Events Following Total Knee Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e23.00267. PMID: 39436712, PMCID: PMC11498930, DOI: 10.5435/jaaosglobal-d-23-00267.Peer-Reviewed Original ResearchConceptsAtopic dermatitisAdverse eventsOdds of pneumoniaTotal knee arthroplastyPerioperative outcomes of patientsModerate-to-severe diseaseIncreased oddsEmergency departmentUrinary tract infectionChronic inflammatory skin conditionOutcomes of patientsLog-rank testRisk of adverse eventsInflammatory skin conditionIncreased odds of pneumoniaKnee arthroplastyTotal knee arthroplasty patientsPerioperative outcomesImmunosuppressive medicationsTract infectionsAggregate adverse eventsAdult patientsImpact of atopic dermatitisPatient characteristicsMultivariate analysisHepatitis C and its treatment in patients with psoriasis: a propensity-matched case-control study
Zhu H, Shaw V, Cohen J. Hepatitis C and its treatment in patients with psoriasis: a propensity-matched case-control study. Archives Of Dermatological Research 2024, 316: 580. PMID: 39207533, DOI: 10.1007/s00403-024-03340-2.Peer-Reviewed Original ResearchAnti-Interleukin-23 Autoantibodies in Adult-Onset Immunodeficiency.
Cohen J, Damsky W. Anti-Interleukin-23 Autoantibodies in Adult-Onset Immunodeficiency. New England Journal Of Medicine 2024, 391: 188-189. PMID: 38986070, DOI: 10.1056/nejmc2404977.Peer-Reviewed Original ResearchDermatologist and pharmacist perspectives of a collaborative co-management program
Sirotich E, Katini S, Stroedecke N, Luon S, Cohen J. Dermatologist and pharmacist perspectives of a collaborative co-management program. Archives Of Dermatological Research 2024, 316: 460. PMID: 38967646, DOI: 10.1007/s00403-024-03202-x.Peer-Reviewed Original ResearchAssociation between psoriasis and obsessive-compulsive disorder: a case-control study in the All of Us research program
Craver A, Chen G, Fan R, Levey D, Cohen J. Association between psoriasis and obsessive-compulsive disorder: a case-control study in the All of Us research program. Archives Of Dermatological Research 2024, 316: 280. PMID: 38796663, DOI: 10.1007/s00403-024-03112-y.Peer-Reviewed Original ResearchBarriers to care and health-related quality of life among US adults with several common chronic inflammatory skin diseases: a cross-sectional analysis of the NIH All of Us Research Program
Nock M, Barbieri J, Cohen J. Barriers to care and health-related quality of life among US adults with several common chronic inflammatory skin diseases: a cross-sectional analysis of the NIH All of Us Research Program. Archives Of Dermatological Research 2024, 316: 201. PMID: 38775812, DOI: 10.1007/s00403-024-02954-w.Peer-Reviewed Original ResearchConceptsHealth-related quality of lifeHealth-related qualityUS adultsQuality of lifeSocial determinants of healthDeterminants of healthUs Research ProgramCross-sectional analysisNational Institutes of HealthSocial determinantsPhysician careInstitutes of HealthImpact of barriersCost barriersHRQoLAdultsNational InstituteHealthChronic inflammatory skin diseaseBarriersAoURPCarePhysiciansLifeInflammatory skin diseaseBiologics for Psoriasis
Wride A, Chen G, Spaulding S, Tkachenko E, Cohen J. Biologics for Psoriasis. Dermatologic Clinics 2024, 42: 339-355. PMID: 38796266, DOI: 10.1016/j.det.2024.02.001.Peer-Reviewed Original ResearchConceptsIL-23IL-17ALong-term risk-benefit profileTNF-aLong-term adverse eventsIL-23 inhibitorsTumor necrosis factor-alphaP19 subunit of IL-23Risk-benefit profileSubunit of IL-23TNF-a inhibitorsTreatment of psoriasisNecrosis factor-alphaHigher Psoriasis AreaRates of short-termIL-12/23Psoriasis AreaIL-17FAdverse eventsIL-12IL-17Factor-alphaP19 subunitInjectable biologicsP40 subunitComorbid psychiatric disease significantly mediates increased rates of alcohol use disorder among patients with inflammatory and pigmentary skin disorders: a case–control study in the All of Us Research Program
Kamal K, Xiang D, Young K, Mostaghimi A, Barbieri J, Cohen J, Theodosakis N. Comorbid psychiatric disease significantly mediates increased rates of alcohol use disorder among patients with inflammatory and pigmentary skin disorders: a case–control study in the All of Us Research Program. Archives Of Dermatological Research 2024, 316: 79. PMID: 38252292, DOI: 10.1007/s00403-023-02803-2.Peer-Reviewed Original ResearchConceptsAlcohol use disorderComorbid psychiatric diseaseUse disorderPsychiatric diseasesRates of alcohol use disordersOdds of alcohol use disordersContribution of depressionPhysical health effectsComorbid depressionMediation analysisAnxietyDepressionDisordersDermatological diseasesCase-control studyPigmentary skin disorderMultivariate logistic regressionHidradenitis suppurativaAtopic dermatitisSkin disordersPigmentary disordersCase-control modelIncreased oddsPatientsUs Research ProgramPsoriasis associated with inflammatory bowel disease: a cross‐sectional analysis in the NIH All of Us Research Program
Joel M, Wride A, Cohen J. Psoriasis associated with inflammatory bowel disease: a cross‐sectional analysis in the NIH All of Us Research Program. International Journal Of Dermatology 2024, 63: e82-e83. PMID: 38204174, PMCID: PMC10922412, DOI: 10.1111/ijd.17015.Peer-Reviewed Original Research
2023
Barriers to Care Among Sexual and Gender Minority Individuals With Chronic Inflammatory Skin Diseases in the US
Nock M, Kamal K, Zampella J, Roberson M, Cohen J, Barbieri J. Barriers to Care Among Sexual and Gender Minority Individuals With Chronic Inflammatory Skin Diseases in the US. JAMA Dermatology 2023, 159: 1323-1331. PMID: 37755822, PMCID: PMC10535014, DOI: 10.1001/jamadermatol.2023.3328.Peer-Reviewed Original ResearchConceptsChronic inflammatory skin diseaseInflammatory skin diseaseHealth care practitionersCross-sectional studySGM patientsPrevalence of barriersCare practitionersGender minority patientsSkin diseasesMinority patientsMAIN OUTCOMEHealth careMultivariable logistic regressionHealth care accessMental health careSpecialist careCare accessPatientsUs Research ProgramLogistic regressionCarePrevalenceDiseaseNational InstituteGender minority individualsObsessive–compulsive disorder among patients with atopic dermatitis: a case–control study in the All of Us research program
Chen G, Fan R, Leasure A, Levey D, Damsky W, Cohen J. Obsessive–compulsive disorder among patients with atopic dermatitis: a case–control study in the All of Us research program. Archives Of Dermatological Research 2023, 316: 11. PMID: 38038754, DOI: 10.1007/s00403-023-02767-3.Peer-Reviewed Original ResearchAssociations between ichthyosis and mood disorders: A case-control study in the All of Us Research Program
Chen G, Goldust M, Choate K, Cohen J. Associations between ichthyosis and mood disorders: A case-control study in the All of Us Research Program. Journal Of The American Academy Of Dermatology 2023, 90: 439-440. PMID: 37863200, DOI: 10.1016/j.jaad.2023.10.025.Peer-Reviewed Original ResearchMachine learning analysis of pretreatment skin biopsies predicts nonresponse to dupilumab in patients with eczematous dermatitis
Murphy M, Hwang E, Singh K, Lee T, Cohen J, Damsky W. Machine learning analysis of pretreatment skin biopsies predicts nonresponse to dupilumab in patients with eczematous dermatitis. British Journal Of Dermatology 2023, 190: 132-134. PMID: 37818837, DOI: 10.1093/bjd/ljad389.Peer-Reviewed Original ResearchAssociation of psoriasis and systemic lupus erythematosus and mediation effects of tumor necrosis factor-α inhibitors: A cross-sectional study in the All of Us Research Program
Chen G, Hong S, Ramachandran S, Gehlhausen J, Cohen J. Association of psoriasis and systemic lupus erythematosus and mediation effects of tumor necrosis factor-α inhibitors: A cross-sectional study in the All of Us Research Program. Journal Of The American Academy Of Dermatology 2023, 90: 184-187. PMID: 37734665, DOI: 10.1016/j.jaad.2023.09.028.Peer-Reviewed Original ResearchAssociation of atopic dermatitis with schizophrenia and schizoaffective disorder
Fan R, Chen G, Leasure A, Johnson M, Damsky W, Cohen J. Association of atopic dermatitis with schizophrenia and schizoaffective disorder. Archives Of Dermatological Research 2023, 315: 2731-2733. PMID: 37495709, DOI: 10.1007/s00403-023-02674-7.Peer-Reviewed Original ResearchAssociation between uveitis and Lichen planus in the all of us research program
Murphy M, Heyang M, Fan R, Leasure A, Damsky W, Cohen J. Association between uveitis and Lichen planus in the all of us research program. Archives Of Dermatological Research 2023, 315: 2729-2730. PMID: 37488318, DOI: 10.1007/s00403-023-02675-6.Peer-Reviewed Original ResearchIncreased risk of depression in patients with discoid lupus erythematosus: a nested, case–control study in the All of Us Research Program
Chen G, Shaw K, Sanchez-Melendez S, Vleugels R, Cohen J. Increased risk of depression in patients with discoid lupus erythematosus: a nested, case–control study in the All of Us Research Program. British Journal Of Dermatology 2023, 189: 628-629. PMID: 37461222, DOI: 10.1093/bjd/ljad239.Peer-Reviewed Original ResearchConceptsDiscoid lupus erythematosusCase-control studyRisk of depressionLupus erythematosusMajor depressive disorderHealth Research programmeDepressive disorderUs Research ProgramPatientsUS databaseLarge-scale studiesNational InstituteErythematosusRiskHeterogeneous populationDepressionFirst large-scale studyDemographic groupsAssessment of Treatment-Relevant Immune Biomarkers in Psoriasis and Atopic Dermatitis: Toward Personalized Medicine in Dermatology
Mortlock R, Ma E, Cohen J, Damsky W. Assessment of Treatment-Relevant Immune Biomarkers in Psoriasis and Atopic Dermatitis: Toward Personalized Medicine in Dermatology. Journal Of Investigative Dermatology 2023, 143: 1412-1422. PMID: 37341663, PMCID: PMC10830170, DOI: 10.1016/j.jid.2023.04.005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAtopic dermatitisSkin diseasesInflammatory skin diseaseInflammatory skin conditionImmunologic biomarkersImmune biomarkersPersonalized medicineInflammatory dermatosesImmunologic approachesTherapy selectionSkin conditionsSingle-cell RNA sequencingMolecular profilingBiomarkersTissue stainingPsoriasisDermatitisDiseaseDermatologyRNA sequencingMedicineCurettageDermatosesTherapyPersonalized classificationThe association of cutaneous squamous cell carcinoma and basal cell carcinoma with solid organ transplantation: a cross‐sectional study of the All Of Us Research Program
Belzer A, Leasure A, Cohen J, Perkins S. The association of cutaneous squamous cell carcinoma and basal cell carcinoma with solid organ transplantation: a cross‐sectional study of the All Of Us Research Program. International Journal Of Dermatology 2023, 62: e564-e566. PMID: 37144784, DOI: 10.1111/ijd.16700.Peer-Reviewed Original Research