2024
Comorbid psychiatric disease significantly mediates increased rates of alcohol use disorder among patients with inflammatory and pigmentary skin disorders: a case–control study in the All of Us Research Program
Kamal K, Xiang D, Young K, Mostaghimi A, Barbieri J, Cohen J, Theodosakis N. Comorbid psychiatric disease significantly mediates increased rates of alcohol use disorder among patients with inflammatory and pigmentary skin disorders: a case–control study in the All of Us Research Program. Archives Of Dermatological Research 2024, 316: 79. PMID: 38252292, DOI: 10.1007/s00403-023-02803-2.Peer-Reviewed Original ResearchConceptsAlcohol use disorderComorbid psychiatric diseaseUse disorderPsychiatric diseasesRates of alcohol use disordersOdds of alcohol use disordersContribution of depressionPhysical health effectsComorbid depressionMediation analysisAnxietyDepressionDisordersDermatological diseasesCase-control studyPigmentary skin disorderMultivariate logistic regressionHidradenitis suppurativaAtopic dermatitisSkin disordersPigmentary disordersCase-control modelIncreased oddsPatientsUs Research Program
2021
Cytokine RNA In Situ Hybridization Permits Individualized Molecular Phenotyping in Biopsies of Psoriasis and Atopic Dermatitis
Wang A, Fogel AL, Murphy MJ, Panse G, McGeary MK, McNiff JM, Bosenberg M, Vesely MD, Cohen JM, Ko CJ, King BA, Damsky W. Cytokine RNA In Situ Hybridization Permits Individualized Molecular Phenotyping in Biopsies of Psoriasis and Atopic Dermatitis. JID Innovations 2021, 1: 100021. PMID: 34909719, PMCID: PMC8659380, DOI: 10.1016/j.xjidi.2021.100021.Peer-Reviewed Original ResearchAtopic dermatitisAtopic dermatitis casesInflammatory skin diseaseInflammatory skin disorderSubset of casesSitu hybridizationCytokine RNARoutine biopsyCytokine expressionPredominant cytokinePsoriasis casesCytokine targetsTreatment selectionDermatitis casesSkin disordersPsoriasis biomarkersSkin diseasesIndividual cytokinesIndividualized evaluationPsoriasisBiopsyBulk RNA sequencingCytokinesMolecular phenotypingPatients