1991
Mechanism of mercurial inhibition of sodium-coupled alanine uptake in liver plasma membrane vesicles from Raja erinacea
Sellinger M, Ballatori N, Boyer J. Mechanism of mercurial inhibition of sodium-coupled alanine uptake in liver plasma membrane vesicles from Raja erinacea. Toxicology And Applied Pharmacology 1991, 107: 369-376. PMID: 1994517, DOI: 10.1016/0041-008x(91)90216-2.Peer-Reviewed Original ResearchConceptsDependent alanine uptakePlasma membrane vesiclesMembrane vesiclesAlanine uptakePrimitive vertebratesPlasma membraneTransport proteinsConcentration-dependent mechanismLiver plasma membrane vesiclesMicroM HgCl2Mammalian hepatocytesAlanine carrierSulfhydryl groupsLittle skateMembrane integrityRaja erinaceaDirect interactionVesiclesVesicle integrityMembrane permeabilityMercurial inhibitionUptake rateDose-dependent mannerHgCl2 concentrationsLiver plasma membranes
1990
Cryptic na+, k+‐atpase activity in rat liver canalicular plasma membranes: Evidence for its basolateral origin
Sellinger M, Barrett C, Malle P, Gordon E, Boyer J. Cryptic na+, k+‐atpase activity in rat liver canalicular plasma membranes: Evidence for its basolateral origin. Hepatology 1990, 11: 223-229. PMID: 2155168, DOI: 10.1002/hep.1840110211.Peer-Reviewed Original ResearchConceptsFree-flow electrophoresisMembrane-fluidizing agentSurface chargeBasolateral enzymeBasolateral marker enzymeSmall contaminantsRat liver canalicular plasma membranesSmall amountRoutine assayAnodeSucrose density centrifugationMembraneElectrophoresisCanalicular liver plasma membranesEnzymeMembrane preparationsContaminantsPreparationChargeCanalicular markerPrecipitationLiver plasma membranesFractionActivity
1987
Ursodeoxycholate stimulates Na+-H+ exchange in rat liver basolateral plasma membrane vesicles.
Moseley R, Ballatori N, Smith D, Boyer J. Ursodeoxycholate stimulates Na+-H+ exchange in rat liver basolateral plasma membrane vesicles. Journal Of Clinical Investigation 1987, 80: 684-690. PMID: 3040805, PMCID: PMC442291, DOI: 10.1172/jci113122.Peer-Reviewed Original Research
1984
Mechanism and subcellular site of bilirubin diglucuronide formation in rat liver.
Gordon E, Meier P, Goresky C, Boyer J. Mechanism and subcellular site of bilirubin diglucuronide formation in rat liver. Journal Of Biological Chemistry 1984, 259: 5500-5506. PMID: 6715357, DOI: 10.1016/s0021-9258(18)91040-9.Peer-Reviewed Original ResearchConceptsBilirubin diglucuronideBilirubin monoglucuronideBilirubin IX alpha monoglucuronideCanalicular liver plasma membranesRat liverLiver plasma membranesNADPH-cytochrome c reductase activityHepatic conversionBilirubinBilirubin diglucuronide formationHepatic microsomesUDP-glucuronateMonoglucuronide
1979
Effect of chlorpromazine on hepatic perfusion and bile secretory function in the isolated perfused rat liver.
Tavoloni N, Reed J, Hruban Z, Boyer J. Effect of chlorpromazine on hepatic perfusion and bile secretory function in the isolated perfused rat liver. Translational Research 1979, 94: 726-41. PMID: 227976.Peer-Reviewed Original ResearchConceptsHepatic perfusionPerfusate flowBile secretionBile acid-independent bile secretionSecretory functionBile acid excretionBile secretory functionRat liverEffect of chlorpromazineLiver 20 minLobar distributionHepatic lobeAcid excretionBaseline valuesPerfusate concentrationConstant infusionHepatic ultrastructureBile acidsControl valuesCPZSodium taurocholateLiverPerfusionGM-1Liver plasma membranes
1977
Effects of chronic choleretic infusions of bile acids on the membrane of the bile canaliculus. A biochemical and morphologic study.
Nemchausky B, Layden T, Boyer J. Effects of chronic choleretic infusions of bile acids on the membrane of the bile canaliculus. A biochemical and morphologic study. Laboratory Investigation 1977, 36: 259-67. PMID: 138767.Peer-Reviewed Original Research