2009
Tumor Regression following DNA Vaccination and Regulatory T Cell Depletion in neu Transgenic Mice Leads to an Increased Risk for Autoimmunity
Jacob JB, Kong YC, Nalbantoglu I, Snower DP, Wei WZ. Tumor Regression following DNA Vaccination and Regulatory T Cell Depletion in neu Transgenic Mice Leads to an Increased Risk for Autoimmunity. The Journal Of Immunology 2009, 182: 5873-5881. PMID: 19380836, PMCID: PMC3833444, DOI: 10.4049/jimmunol.0804074.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCancer VaccinesCell Line, TumorFemaleGenetic Predisposition to DiseaseLymphocyte DepletionMammary Neoplasms, ExperimentalMiceMice, Inbred BALB CMice, TransgenicNIH 3T3 CellsRatsReceptor, ErbB-2Remission InductionThyroglobulinThyroiditis, AutoimmuneT-Lymphocytes, RegulatoryVaccines, DNAConceptsRegulatory T-cell depletionT-cell depletionDNA vaccinationTumor regressionTreg depletionCell depletionBALB/c miceAnti-tumor immunityNeu transgenic miceAutoimmune manifestationsImmunotherapeutic regimensAutoimmune thyroiditisTolerant miceMouse thyroglobulinTumor immunityCD25 mAbComplete regressionImmune reactivityAutoimmune diseasesC miceCancer immunotherapyCancer patientsClinical trialsFemale miceLong-term protection
2007
Ischemic Preconditioning and Intermittent Clamping Increase the Tolerance of Fatty Liver to Hepatic Ischemia-Reperfusion Injury in the Rat
Saidi R, Chang J, Brooks S, Nalbantoglu I, Adsay V, Jacobs M. Ischemic Preconditioning and Intermittent Clamping Increase the Tolerance of Fatty Liver to Hepatic Ischemia-Reperfusion Injury in the Rat. Transplantation Proceedings 2007, 39: 3010-3014. PMID: 18089311, DOI: 10.1016/j.transproceed.2007.09.044.Peer-Reviewed Original ResearchConceptsContinuous clampingIntermittent clampingIschemic preconditioningR injuryLiver I/R injuryAspartate aminotransferaseLiver ischemia-reperfusion injurySerum IL-6 levelsHours of reperfusionIL-6 levelsIschemia-reperfusion injuryCause of morbidityMale Zucker ratsHepatic ischemiaSerum interleukinHepatocellular injurySerum levelsIschemic periodUntoward sequelaeHepatic steatosisLiver surgeryZucker ratsCellular injuryInjuryMinutesThe effect of methylprednisolone on warm ischemia-reperfusion injury in the liver
Saidi RF, Chang J, Verb S, Brooks S, Nalbantoglu I, Adsay V, Jacobs MJ. The effect of methylprednisolone on warm ischemia-reperfusion injury in the liver. The American Journal Of Surgery 2007, 193: 345-348. PMID: 17320532, DOI: 10.1016/j.amjsurg.2006.09.017.Peer-Reviewed Original ResearchConceptsIschemia-reperfusion injuryR injuryInterleukin-6Continuous clampingIschemic preconditioningSteatotic liversInflammatory responseNormal liverAspartate aminotransferaseLiver ischemia-reperfusion injuryWarm ischemia-reperfusion injuryMale Sprague-Dawley ratsSerum IL-6Serum interleukin-6Hours of reperfusionEffect of methylprednisoloneCause of morbiditySprague-Dawley ratsIntravenous methylprednisoloneHepatic ischemiaIschemia inductionSerum levelsIschemic controlsIschemic periodLiver ischemia