2016
Characterization of Colorectal Cancer Development in Apcmin/+ Mice
Nalbantoglu I, Blanc V, Davidson NO. Characterization of Colorectal Cancer Development in Apcmin/+ Mice. Methods In Molecular Biology 2016, 1422: 309-327. PMID: 27246043, PMCID: PMC5061497, DOI: 10.1007/978-1-4939-3603-8_27.ChaptersConceptsDextran sulfate sodiumCancer developmentCommon pathologic lesionsBile acid supplementationExperimental colorectal cancerColorectal cancer developmentHigh-fat dietColon cancer developmentSulfate sodiumColorectal cancerFat dietAcid supplementationPathologic lesionsTherapeutic aspectsIntestinal neoplasiaC57BL/6J backgroundEnvironmental modifiersExperimental modelMiceExcellent experimental modelTissue processingNeoplasiaLesionsCancer
2014
Histological features and severity of oxaliplatin‐induced liver injury and clinical associations
Nalbantoglu I, Tan B, Linehan D, Gao F, Brunt E. Histological features and severity of oxaliplatin‐induced liver injury and clinical associations. Journal Of Digestive Diseases 2014, 15: 553-560. PMID: 25060628, DOI: 10.1111/1751-2980.12177.Peer-Reviewed Original ResearchConceptsOxaliplatin-induced liver injuryHigher injury scoresInjury scoreLiver injuryAspartate aminotransferaseElevated preoperative aspartate aminotransferaseShort-term postoperative complicationsSerum liver enzyme levelsColorectal carcinoma liver metastasesAbnormal AST levelsComponent of chemotherapyHepatic sinusoidal injuryPreoperative aspartate aminotransferaseMetastatic colorectal carcinomaLiver enzyme levelsLiver injury scoreBody mass indexLong-term outcomesSinusoidal lining cellsManifestations of injuryLight microscopic lesionsAlkaline phosphatase levelsInjury scoring systemNon-tumor liverLower injury scores