2018
Unique causes of esophageal inflammation: a histopathologic perspective
Gopal P, Gibson JA, Lisovsky M, Nalbantoglu I. Unique causes of esophageal inflammation: a histopathologic perspective. Annals Of The New York Academy Of Sciences 2018, 1434: 219-226. PMID: 29766506, DOI: 10.1111/nyas.13732.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsEsophageal mucosal biopsiesEsophageal inflammationMucosal biopsiesMedication-induced esophageal injuryCause of esophagitisSymptoms of esophagitisHerpes simplex virusBacterial esophagitisInfectious esophagitisSloughing esophagitisEsophageal manifestationsReflux esophagitisEosinophilic esophagitisEsophageal injuryHistopathologic featuresPathologic diagnosisHistopathologic perspectiveCommon causeDermatologic diseasesEsophagitisSimplex virusUnique causeBiopsyInflammationCause
2012
Transient Inability to Manage Proteobacteria Promotes Chronic Gut Inflammation in TLR5-Deficient Mice
Carvalho FA, Koren O, Goodrich JK, Johansson ME, Nalbantoglu I, Aitken JD, Su Y, Chassaing B, Walters WA, González A, Clemente JC, Cullender TC, Barnich N, Darfeuille-Michaud A, Vijay-Kumar M, Knight R, Ley RE, Gewirtz AT. Transient Inability to Manage Proteobacteria Promotes Chronic Gut Inflammation in TLR5-Deficient Mice. Cell Host & Microbe 2012, 12: 139-152. PMID: 22863420, PMCID: PMC4310462, DOI: 10.1016/j.chom.2012.07.004.Peer-Reviewed Original ResearchConceptsChronic colitisGenetic influencing factorsTLR5-deficient miceChronic gut inflammationLow-grade inflammationMucosal immune systemInnate immune deficiencyProinflammatory gene expressionWild-type miceContribution of microbiotaTransient high levelsGut inflammationImmune deficiencyIntestinal microbiotaColitisGut microbiotaImmune systemMice displayUnstable microbiotaGut epitheliumTransient inabilityMicrobiotaInflammationBreakdown of homeostasisIncomplete penetrance