Deciphering craniopharyngioma subtypes: Single-cell analysis of tumor microenvironment and immune networks
Matsuda T, Kono T, Taki Y, Sakuma I, Fujimoto M, Hashimoto N, Kawakami E, Fukuhara N, Nishioka H, Inoshita N, Yamada S, Nakamura Y, Horiguchi K, Miki T, Higuchi Y, Tanaka T. Deciphering craniopharyngioma subtypes: Single-cell analysis of tumor microenvironment and immune networks. IScience 2024, 111068. DOI: 10.1016/j.isci.2024.111068.Peer-Reviewed Original ResearchTumor microenvironmentAnalysis of tumor microenvironmentImmune responseOccurrence of diabetes insipidusExpression of pro-inflammatory markersCell-cell interactionsPro-inflammatory markersComprehensive cell atlasM2 macrophage ratioSquamous papillaryDiabetes insipidusTumor cellsSingle cell RNA sequencingMacrophage ratioM1 macrophagesM2 macrophagesPituitary structureCell RNA sequencingCellular compositionSingle-cell clusteringCell typesDiverse cell typesTumorGene expression patternsMolecular characteristics