2023
Sequre: a high-performance framework for secure multiparty computation enables biomedical data sharing
Smajlović H, Shajii A, Berger B, Cho H, Numanagić I. Sequre: a high-performance framework for secure multiparty computation enables biomedical data sharing. Genome Biology 2023, 24: 5. PMID: 36631897, PMCID: PMC9832703, DOI: 10.1186/s13059-022-02841-5.Peer-Reviewed Original ResearchConceptsSecure multiparty computationHigh-performance frameworkMultiparty computationMPC applicationsSensitive biomedical dataRapid application developmentPython programming languageCompile-time optimizationBiomedical data sharingCryptographic toolsApplication developmentInvolved entitiesProgramming languageBioinformatics tasksData sharingBiomedical dataPrivate informationComputationFrameworkUsabilitySharingApplicationsSyntaxPerformanceTask
2022
k-SALSA: k-Anonymous Synthetic Averaging of Retinal Images via Local Style Alignment
Jeon M, Park H, Kim H, Morley M, Cho H. k-SALSA: k-Anonymous Synthetic Averaging of Retinal Images via Local Style Alignment. Lecture Notes In Computer Science 2022, 13681: 661-678. PMID: 37525827, PMCID: PMC10388376, DOI: 10.1007/978-3-031-19803-8_39.Peer-Reviewed Original ResearchStyle alignmentMembership inference attacksRetinal imagesGenerative adversarial networkPotential of machineRetinal image analysisRetinal fundus imagesK-anonymityInference attacksPrivacy notionPrivate datasetAdversarial networkData sharingBenchmark datasetsTraining dataClassification performanceModern machineArt techniquesSource imagesImage fidelityFundus imagesPrior workVisual patternsImage analysisImagesMechanisms for Hiding Sensitive Genotypes With Information-Theoretic Privacy
Ye F, Cho H, Rouayheb S. Mechanisms for Hiding Sensitive Genotypes With Information-Theoretic Privacy. IEEE Transactions On Information Theory 2022, 68: 4090-4105. PMID: 37283781, PMCID: PMC10243750, DOI: 10.1109/tit.2022.3156276.Peer-Reviewed Original ResearchInformation-theoretic privacyGenomic data sharingOptimal greedy algorithmCritical health-related informationEfficient algorithmic implementationPrivacy leakagePrivacy mechanismsPrivacy problemsPersonal genomics servicesData sharingPrivacyGreedy algorithmStandard modeling approachesComplexity polynomialOptimal utilityAlgorithmic implementationProcessing orderHealth-related informationStraightforward solutionMarkov modelGenomic dataNearby positionsModeling approachGenomic servicesUsers
2020
Mechanisms for Hiding Sensitive Genotypes with Information-Theoretic Privacy
Ye F, Cho H, Rouayheb S. Mechanisms for Hiding Sensitive Genotypes with Information-Theoretic Privacy. 2020, 00: 902-907. DOI: 10.1109/isit44484.2020.9174492.Peer-Reviewed Original ResearchInformation-theoretic privacyGenomic data sharingCritical health-related informationEfficient algorithmic implementationHidden Markov ModelPersonal genomics servicesData sharingGenomic privacyPrivacyAlgorithmic implementationSuch servicesHealth-related informationStraightforward solutionMarkov modelGenomic dataServicesGenomic servicesInformationSharingImplementationCorrelation structureData
2019
Emerging technologies towards enhancing privacy in genomic data sharing
Berger B, Cho H. Emerging technologies towards enhancing privacy in genomic data sharing. Genome Biology 2019, 20: 128. PMID: 31262363, PMCID: PMC6604426, DOI: 10.1186/s13059-019-1741-0.Commentaries, Editorials and Letters
2018
Realizing private and practical pharmacological collaboration
Hie B, Cho H, Berger B. Realizing private and practical pharmacological collaboration. Science 2018, 362: 347-350. PMID: 30337410, PMCID: PMC6519716, DOI: 10.1126/science.aat4807.Peer-Reviewed Original ResearchConceptsArt DTI prediction methodsDrug-target interactionsDTI prediction methodsIntellectual property concernsCryptographic toolsData privacyData sharingMultiple entitiesReal datasetsOpen sharingProperty concernsPrediction methodSharingDatasetPredictive modelPrivacyProtocolConfidentialityBiomedical researchCollaborationToolDataEntities