2001
Defining the specific physiological requirements for c-Myc in T cell development
Douglas N, Jacobs H, Bothwell A, Hayday A. Defining the specific physiological requirements for c-Myc in T cell development. Nature Immunology 2001, 2: 307-315. PMID: 11276201, DOI: 10.1038/86308.Peer-Reviewed Original ResearchConceptsDevelopmental gene expressionC-MycSpecific physiological requirementsMYC family membersT cell developmentAbstractc-MycN-myc expressionGene expressionDeregulated expressionCell developmentCell growthPhysiological requirementsAge-dependent mannerThymocyte maturationDN stageNormal lymphocytesExpressionNonredundant contributionsDistinct patternsFamily membersCellsLymphomagenesisMaturationLymphocytes
2000
Hex expression suggests a role in the development and function of organs derived from foregut endoderm
Bogue C, Ganea G, Sturm E, Ianucci R, Jacobs H. Hex expression suggests a role in the development and function of organs derived from foregut endoderm. Developmental Dynamics 2000, 219: 84-89. PMID: 10974674, DOI: 10.1002/1097-0177(2000)9999:9999<::aid-dvdy1028>3.0.co;2-5.Peer-Reviewed Original ResearchConceptsExtrahepatic biliary ductsMature animalsMaintenance of functionThymus originatesAdult thyroidDorsal pancreatic budLung expressionBile ductBiliary ductsThymic expressionFunction of organsDuct epitheliumLungThyroidE16.5 embryosLiverEpithelial cellsThymusSeptum transversumMesenchymal cellsPotential roleHex expressionDetectable levelsPharyngeal pouchesOrgans