Betamethasone Increases Pulmonary Compliance in Part by Surfactant-Independent Mechanisms in Preterm Rabbits
Fiascone J, Jacobs H, Moya F, Mercurio M, Lima D. Betamethasone Increases Pulmonary Compliance in Part by Surfactant-Independent Mechanisms in Preterm Rabbits. Pediatric Research 1987, 22: 730-735. PMID: 3431959, DOI: 10.1203/00006450-198712000-00024.Peer-Reviewed Original ResearchConceptsAntenatal corticosteroidsIntratracheal surfactantPulmonary complianceDynamic complianceAlveolar surfactant contentHigher dynamic complianceAntenatal exposurePreterm rabbitsPreterm animalsSingle therapyAlveolar lavageTidal volumeCorticosteroidsFirst breathFetusesDay 25Compliance studiesVentilationRabbitsComplianceCompliance measurementsLavageGestationBetamethasoneTherapyThresholds for physiological effects of plasma catecholamines in fetal sheep
Padbury J, Ludlow J, Ervin M, Jacobs H, Humme J. Thresholds for physiological effects of plasma catecholamines in fetal sheep. American Journal Of Physiology 1987, 252: e530-e537. PMID: 3565562, DOI: 10.1152/ajpendo.1987.252.4.e530.Peer-Reviewed Original ResearchConceptsBlood pressurePlasma concentrationsFetal sheepPg/Plasma free fatty acidsDiastolic blood pressureSystolic blood pressurePlasma catecholamine levelsFull-term animalsInfusion of norepinephrineMinimum plasma concentrationDose-response curvePlasma catecholamine valuesInfused norepinephrineHigher peak responsesNeonatal adaptationCatecholamine levelsPlasma catecholaminesPreterm animalsFree fatty acidsGlucose levelsE concentrationsCatecholamine valuesNorepinephrineMarked increase