1985
Effects of high-frequency and conventional ventilation on the premature lamb lung
Solimano A, Bryan C, Jobe A, Ikegami M, Jacobs H. Effects of high-frequency and conventional ventilation on the premature lamb lung. Journal Of Applied Physiology 1985, 59: 1571-1577. PMID: 3840801, DOI: 10.1152/jappl.1985.59.5.1571.Peer-Reviewed Original ResearchConceptsMean airway pressureConventional mechanical ventilationProtein leakPremature lamb lungsFetal lung fluidRespiratory distress syndromeDays gestational ageDegree of leakHigh-frequency oscillationsGroups of lambsAirway pressureCesarean sectionDistress syndromeGestational ageConventional ventilationMechanical ventilationPathological findingsLung diseaseBlood gasesImmature lungVentilator settingsEpithelial necrosisBlood gasLung sectionsTracer doseAccumulation of Alveolar Surfactant Following Delivery and Ventilation of Premature Lambs
Jacobs H, Jobe A, Ikegami M, Jones S. Accumulation of Alveolar Surfactant Following Delivery and Ventilation of Premature Lambs. Experimental Lung Research 1985, 8: 125-140. PMID: 3839748, DOI: 10.3109/01902148509057517.Peer-Reviewed Original ResearchConceptsAlveolar washTreatment doseAlveolar surfactantMean gestational ageArterial blood gasPeak inspiratory pressureMin of ageSurfactant pool sizeAlveolar surfactant accumulationPhosphatidylcholine specific activityCesarean sectionPremature lambsGestational agePremature lungInspiratory pressureIntratracheal administrationBlood gasTrace doseDilution techniqueDoseAgeAirwayPool sizeBirthAccumulation of surfactant
1983
Cardiovascular Effects of Surfactant Suspensions Given by Tracheal Instillation to Premature Lambs
Jobe A, Jacobs H, Ikegami M, Jones S. Cardiovascular Effects of Surfactant Suspensions Given by Tracheal Instillation to Premature Lambs. Pediatric Research 1983, 17: 444-448. PMID: 6553821, DOI: 10.1203/00006450-198306000-00002.Peer-Reviewed Original ResearchConceptsSurfactant instillationPremature lambsOnly ventilator settingPulmonary artery pressureDays gestational ageSurfactant treatmentArtery pressureCesarean sectionRespiratory supportCardiovascular effectsLung functionGestational ageCardiovascular statusInspiratory pressureRespiratory statusTransient deteriorationCardiac outputAortic pressureTracheal instillationVentilator settingsInfant ventilatorRegional bloodHeart rateInstillationBody weight