2023
Sex Difference in Outcomes of Acute Myocardial Infarction in Young Patients
Sawano M, Lu Y, Caraballo C, Mahajan S, Dreyer R, Lichtman J, D'Onofrio G, Spatz E, Khera R, Onuma O, Murugiah K, Spertus J, Krumholz H. Sex Difference in Outcomes of Acute Myocardial Infarction in Young Patients. Journal Of The American College Of Cardiology 2023, 81: 1797-1806. PMID: 37137590, DOI: 10.1016/j.jacc.2023.03.383.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionNoncardiac hospitalizationsSubdistribution HRYounger patientsMyocardial infarctionSex differencesYoung womenCause-specific hospitalizationsCause of hospitalizationWorse health statusSignificant sex disparityNoncardiovascular hospitalizationsVIRGO StudyIndex episodeAdverse outcomesIncidence rateHospitalizationHigh riskSex disparitiesHealth statusPatientsU.S. hospitalsWomenInfarctionOutcomes
2019
Evaluation of 30-Day Hospital Readmission and Mortality Rates Using Regression-Discontinuity Framework
Khera R, Wang Y, Nasir K, Lin Z, Krumholz HM. Evaluation of 30-Day Hospital Readmission and Mortality Rates Using Regression-Discontinuity Framework. Journal Of The American College Of Cardiology 2019, 74: 219-234. PMID: 31296295, PMCID: PMC8669780, DOI: 10.1016/j.jacc.2019.04.060.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHospital Readmissions Reduction ProgramHeart failureReadmission ratesElderly Medicare feeMedian readmission rateReadmissions Reduction ProgramPost-discharge daysInstitution of strategiesHospital readmissionReadmission riskMyocardial infarctionReadmission reductionCardiovascular conditionsEligible hospitalsMedicare feeReadmission penaltiesMortality rateDay 1Day 30ReadmissionDay 60HospitalU.S. hospitalsHospitalizationEvaluation of the Patient Request Process for Radiology Imaging in U.S. Hospitals.
Lye CT, Krumholz HM, Eckroate JE, Daniel JG, deBronkart D, Mann MK, Hsiao AL, Forman HP. Evaluation of the Patient Request Process for Radiology Imaging in U.S. Hospitals. Radiology 2019, 292: 409-413. PMID: 31184560, DOI: 10.1148/radiol.2019190473.Peer-Reviewed Original Research
2016
Treatment for Multiple Acute Cardiopulmonary Conditions in Older Adults Hospitalized with Pneumonia, Chronic Obstructive Pulmonary Disease, or Heart Failure
Dharmarajan K, Strait KM, Tinetti ME, Lagu T, Lindenauer PK, Lynn J, Krukas MR, Ernst FR, Li SX, Krumholz HM. Treatment for Multiple Acute Cardiopulmonary Conditions in Older Adults Hospitalized with Pneumonia, Chronic Obstructive Pulmonary Disease, or Heart Failure. Journal Of The American Geriatrics Society 2016, 64: 1574-1582. PMID: 27448329, PMCID: PMC4988873, DOI: 10.1111/jgs.14303.Peer-Reviewed Original ResearchMeSH KeywordsAdrenal Cortex HormonesAgedAged, 80 and overAnti-Bacterial AgentsCardiotonic AgentsCohort StudiesComorbidityCross-Sectional StudiesDiureticsDrug Therapy, CombinationFemaleHeart FailureHospitalizationHumansMalePneumoniaPulmonary Disease, Chronic ObstructiveRetrospective StudiesUnited StatesVasodilator AgentsConceptsChronic obstructive pulmonary diseaseAcute cardiopulmonary conditionsObstructive pulmonary diseaseHeart failureCardiopulmonary conditionsOlder adultsPulmonary diseasePremier Research DatabaseEpisodes of pneumoniaRetrospective cohort studyReal-world treatmentHF hospitalizationCohort studyHospital daysPneumonia hospitalizationsCOPD hospitalizationsClinical syndromeAcute conditionsPneumoniaDiagnostic uncertaintyResearch DatabaseHospitalizationDiagnostic categoriesU.S. hospitalsAdults
2014
Strategies to reduce hospital 30-day risk-standardized mortality rates for patients with acute myocardial infarction: a cross-sectional and longitudinal survey
Bradley EH, Sipsma H, Brewster AL, Krumholz HM, Curry L. Strategies to reduce hospital 30-day risk-standardized mortality rates for patients with acute myocardial infarction: a cross-sectional and longitudinal survey. BMC Cardiovascular Disorders 2014, 14: 126. PMID: 25252826, PMCID: PMC4182840, DOI: 10.1186/1471-2261-14-126.Peer-Reviewed Original ResearchMeSH KeywordsCooperative BehaviorCross-Sectional StudiesEmergency Medical ServicesEmergency Medical TechniciansHealth Care SurveysHospital MortalityHospitalsHumansInservice TrainingInterdisciplinary CommunicationLongitudinal StudiesMedical Order Entry SystemsMyocardial InfarctionOrganizational CulturePatient Care TeamQuality ImprovementQuality Indicators, Health CareTime FactorsUnited StatesConceptsAcute myocardial infarctionAMI mortality ratesPercentage of hospitalsMortality rateMyocardial infarctionAMI mortalityHospital AMI mortality ratesRisk-standardized mortality ratesEmergency medical services (EMS) providersHospital strategiesCross-sectional surveyPhysician order entryBackgroundSurvival ratesAMI careMedical service providersResultsBetween 2010HospitalU.S. hospitalsOrder entryRegular trainingInfarctionLongitudinal analysisHospital performanceMortalityCurrent useVariation in Hospital-Level Risk-Standardized Complication Rates Following Elective Primary Total Hip and Knee Arthroplasty
Bozic KJ, Grosso LM, Lin Z, Parzynski CS, Suter LG, Krumholz HM, Lieberman JR, Berry DJ, Bucholz R, Han L, Rapp MT, Bernheim S, Drye EE. Variation in Hospital-Level Risk-Standardized Complication Rates Following Elective Primary Total Hip and Knee Arthroplasty. Journal Of Bone And Joint Surgery 2014, 96: 640-647. PMID: 24740660, DOI: 10.2106/jbjs.l.01639.Peer-Reviewed Original ResearchConceptsElective total hip arthroplastyTotal hip arthroplastyComplication rateBlack patientsStudy cohortTKA proceduresMedicaid patientsU.S. hospitalsMedicare feeElective primary total hip arthroplastyPrimary total hip arthroplastyElective primary total hipTotal knee arthroplasty proceduresPrimary total hipPeriprosthetic joint infectionKnee arthroplasty proceduresNational Medicare feeHigher proportionHospital-level riskNational Quality ForumCross-sectional analysisHierarchical logistic regressionTKA patientsCommon complicationPatient comorbidities
2008
Contemporary evidence: baseline data from the D2B Alliance
Bradley EH, Nallamothu BK, Stern AF, Byrd JR, Cherlin EJ, Wang Y, Yuan C, Nembhard I, Brush JE, Krumholz HM. Contemporary evidence: baseline data from the D2B Alliance. BMC Research Notes 2008, 1: 23. PMID: 18710480, PMCID: PMC2525646, DOI: 10.1186/1756-0500-1-23.Peer-Reviewed Original ResearchST-segment elevation myocardial infarctionPrimary percutaneous coronary interventionD2B AllianceHospital characteristicsEvidence-based strategiesD2B timeU.S. hospitalsElevation myocardial infarctionPercutaneous coronary interventionMultivariate logistic regressionCross-sectional studyBalloon (D2B) AllianceCoronary interventionPrompt treatmentMyocardial infarctionHospitalWeb-based surveyLogistic regressionBaseline dataPatientsKey strategyCurrent practiceBackgroundLessInfarctionResultsOf