2011
Statin Use in Outpatients With Obstructive Coronary Artery Disease
Arnold SV, Spertus JA, Tang F, Krumholz HM, Borden WB, Farmer SA, Ting HH, Chan PS. Statin Use in Outpatients With Obstructive Coronary Artery Disease. Circulation 2011, 124: 2405-2410. PMID: 22064595, PMCID: PMC3527107, DOI: 10.1161/circulationaha.111.038265.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArterial Occlusive DiseasesCardiovascular DiseasesCholesterol, LDLCoronary Artery DiseaseFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedOutpatientsPractice Guidelines as TopicProspective StudiesRegistriesRetrospective StudiesRisk FactorsTreatment OutcomeConceptsObstructive coronary artery diseaseLow-density lipoprotein cholesterol levelsCoronary artery diseaseLipoprotein cholesterol levelsLipid-lowering therapyCholesterol levelsStatin therapyUntreated patientsStatin treatmentArtery diseaseLow-density lipoprotein cholesterol valuesNonstatin lipid-lowering medicationsRobust clinical trial evidenceRecent coronary revascularizationClinical trial evidenceLipid-lowering medicationsRoutine outpatient careLipoprotein cholesterol valuesRate of treatmentNonstatin medicationsNonstatin therapiesOutpatient registryCardiovascular morbidityCoronary revascularizationLipid management
2010
Optimizing statin treatment for primary prevention of coronary artery disease.
Hayward RA, Krumholz HM, Zulman DM, Timbie JW, Vijan S. Optimizing statin treatment for primary prevention of coronary artery disease. Annals Of Internal Medicine 2010, 152: 69-77. PMID: 20083825, DOI: 10.7326/0003-4819-152-2-201001190-00004.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCholesterol, LDLClinical Trials as TopicComputer SimulationCoronary Artery DiseaseDrug Administration ScheduleFemaleGuideline AdherenceHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedPrimary PreventionQuality-Adjusted Life YearsRisk FactorsSensitivity and SpecificityTreatment OutcomeConceptsHigh-dose statinsQuality Enhancement Research InitiativeStatin therapyMore QALYsNational Cholesterol Education Program III guidelinesTreatment approachesCoronary artery disease preventionVeterans Affairs Health Services ResearchDoses of statinsCoronary artery diseaseRisk factor dataAvailable clinical dataYears of treatmentTarget approachBase-case analysisHealth services researchPersons 75 yearsStatin doseStatin trialsCAD eventsStatin treatmentArtery diseaseCAD riskPrimary preventionMyocardial infarction