2002
Representation of the elderly, women, and minorities in heart failure clinical trials.
Heiat A, Gross CP, Krumholz HM. Representation of the elderly, women, and minorities in heart failure clinical trials. JAMA Internal Medicine 2002, 162: 1682-8. PMID: 12153370, DOI: 10.1001/archinte.162.15.1682.Peer-Reviewed Original ResearchConceptsClinical trialsHF RCTsHeart failure clinical trialsCharacteristics of patientsSystolic ejection fractionFuture clinical trialsInvasive diagnostic testsCharacteristics of participantsType of interventionChronic HFHF trialsEjection fractionHF populationExclusion criteriaGeneralizability of evidenceRCTsAdditional trialsPatientsDiagnostic testsTrialsOriginal reportMore participantsPrincipal investigatorWomenPublication year
2001
Do Existing Databases Answer Clinical Questions about Geriatric Cardiovascular Disease and Stroke?
Cheitlin MD, Gerstenblith G, Hazzard WR, Pasternak R, Fried LP, Rich MW, Krumholz HM, Peterson E, Reves JG, McKay C, Saksena S, Shen WK, Akhtar M, Brass LM, Biller J. Do Existing Databases Answer Clinical Questions about Geriatric Cardiovascular Disease and Stroke? The American Journal Of Geriatric Cardiology 2001, 10: 207-223. PMID: 11455241, DOI: 10.1111/j.1076-7460.2003.00696.x.Peer-Reviewed Original ResearchConceptsCardiovascular diseaseYounger patientsChronic coronary artery diseaseExtrapolation of safetyRole of revascularizationChronic heart failurePatients 75 yearsRisk factor modificationCharacteristics of patientsCoronary artery diseaseAcute myocardial infarctionYears of ageCollaborative outcomes researchPrincipal investigatorGeriatric cardiologyValve surgeryArtery diseaseHeart failureCarotid endarterectomyFactor modificationMyocardial infarctionEfficacy dataCardiovascular conditionsClinical questionsAvailable safety