2022
Clinical decision support in cardiovascular medicine
Lu Y, Melnick ER, Krumholz HM. Clinical decision support in cardiovascular medicine. The BMJ 2022, 377: e059818. PMID: 35613721, DOI: 10.1136/bmj-2020-059818.Peer-Reviewed Original ResearchConceptsCardiovascular diseaseCardiovascular careEffectiveness of CDSRisk factor modificationClinical decision support toolQuality of careClinical decision supportClinical outcomesFactor modificationHealth information technologyClinical practicePatient careDiseaseCardiovascular medicineCDS effectivenessCareEffectiveness of deliveryMissed opportunityTreatmentFailureProper evidenceHealthcare processesMedicineEvidencePrevention
2016
Commentary: Diagnostic devices in clinical trials have high stakes for patient care
Rathi VK, Krumholz HM, Ross JS. Commentary: Diagnostic devices in clinical trials have high stakes for patient care. The BMJ 2016, 354: i5197. PMID: 27681285, DOI: 10.1136/bmj.i5197.Commentaries, Editorials and Letters
2008
Consequences of Inadequate Sign-out for Patient Care
Horwitz LI, Moin T, Krumholz HM, Wang L, Bradley EH. Consequences of Inadequate Sign-out for Patient Care. JAMA Internal Medicine 2008, 168: 1755-1760. PMID: 18779462, DOI: 10.1001/archinte.168.16.1755.Peer-Reviewed Original ResearchConceptsHealth care providersClinical conditionsCare providersIntensive care unit transferPatient's clinical conditionCare of patientsHouse staff teamsAdverse eventsImportant adverse consequencesCase reportClinical informationAnticipatory guidancePatientsPatient careUnit transferIterative coding processHouse staffAdverse consequencesSignsCareDaysSessionsProvidersDiagnosisRecipients
2006
Delay in the Diagnosis of Acute Myocardial Infarction: Effect on Quality of Care and Its Assessment
Graff LG, Wang Y, Borkowski B, Tuozzo K, Foody JM, Krumholz HM, Radford MJ. Delay in the Diagnosis of Acute Myocardial Infarction: Effect on Quality of Care and Its Assessment. Academic Emergency Medicine 2006, 13: 931-938. PMID: 16894002, DOI: 10.1197/j.aem.2006.04.016.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAge DistributionAgedAged, 80 and overAngina, UnstableAspirinCohort StudiesConnecticutEvidence-Based MedicineFemaleFibrinolytic AgentsHumansMaleMyocardial InfarctionPatient AdmissionQuality Assurance, Health CareQuality of Health CareRetrospective StudiesTime FactorsConceptsAcute myocardial infarctionAdmission diagnosisBeta blockersQuality of careMyocardial infarctionDiagnosis of AMICharacteristics of patientsPercutaneous coronary interventionPrincipal discharge diagnosisEvidence-based therapiesRate of administrationCoronary interventionCardiac catheterizationDischarge diagnosisPrincipal diagnosisFrequency of delaysDischarge statusPatient careAdmissionAMI diagnosisPatientsDiagnosisMedicare casesCareInfarctionTransfers of Patient Care Between House Staff on Internal Medicine Wards: A National Survey
Horwitz LI, Krumholz HM, Green ML, Huot SJ. Transfers of Patient Care Between House Staff on Internal Medicine Wards: A National Survey. JAMA Internal Medicine 2006, 166: 1173-1177. PMID: 16772243, DOI: 10.1001/archinte.166.11.1173.Peer-Reviewed Original ResearchConceptsTransfer of careInternal medicine residency programsMedicine residency programsPatient careWork-hour regulationsResidency programsResident work hour regulationsInternal medicine wardsMain outcome measuresUS internal medicine residency programsClinical outcomesMedicine wardsPrimary teamOutcome measuresHypothetical patientsSelf-administered surveyResident physiciansCare systemCarePatient informationHouse staffHospitalizationPatientsNational surveyComprehensive transfer
2001
The Connecticut Cardiovascular Consortium: a unique, state-wide research collaboration to advance clinical outcomes in patients with heart disease.
Boden WE, McKay RG, Cabin HS, Radford MJ, Krumholz HM, Zaret BL, Garner L, Bull MB, Fisherkeller M, Kosinski EJ, Krauthamer MJ, Maljanian R, McDowell AV, Sands MJ, Schwartz KV, Seltzer JP, Hager JD. The Connecticut Cardiovascular Consortium: a unique, state-wide research collaboration to advance clinical outcomes in patients with heart disease. Connecticut Medicine 2001, 65: 597-604. PMID: 11702518.Peer-Reviewed Original ResearchConceptsST-segment elevation acute myocardial infarctionPercutaneous coronary interventionClinical outcomesSegment elevation acute myocardial infarctionConnecticut residentsPatient careElevation acute myocardial infarctionUltimate clinical impactHealth care delivery modelsAcute myocardial infarctionCurrent health care policiesClinical outcome assessmentHealth care providersGood clinical practiceHealth care accessDifferent treatment patternsEvidence-based medicineHealth care policyMechanical reperfusionMechanical revascularizationPCI capabilityCoronary interventionFibrinolytic therapyTreatment patternsMyocardial infarction
2000
Utilization and effectiveness of a weight-based heparin nomogram at a large academic medical center.
Balcezak TJ, Krumholz HM, Getnick GS, Vaccarino V, Lin ZQ, Cadman EC. Utilization and effectiveness of a weight-based heparin nomogram at a large academic medical center. The American Journal Of Managed Care 2000, 6: 329-38. PMID: 10977433.Peer-Reviewed Original ResearchConceptsWeight-based nomogramWeight-based heparin nomogramTherapeutic rangeTherapeutic thresholdHeparin nomogramIntravenous heparin therapyProportion of patientsProspective cohort analysisLarge academic medical centerInternal medicine serviceComputerized order entry systemAcademic medical centerEffective patient careSupratherapeutic aPTTsHeparin therapyConsecutive patientsOrder entry systemEfficacious therapyMedical CenterCohort analysisMedicine servicePatient carePhysician behaviorNomogramPatients