2006
Hydroxymethylglutaryl‐CoA Reductase Inhibitors in Older Persons with Acute Myocardial Infarction: Evidence for an Age–Statin Interaction
Foody JM, Rathore SS, Galusha D, Masoudi FA, Havranek EP, Radford MJ, Krumholz HM. Hydroxymethylglutaryl‐CoA Reductase Inhibitors in Older Persons with Acute Myocardial Infarction: Evidence for an Age–Statin Interaction. Journal Of The American Geriatrics Society 2006, 54: 421-430. PMID: 16551308, PMCID: PMC2797316, DOI: 10.1111/j.1532-5415.2005.00635.x.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAged, 80 and overAtorvastatinCholesterol, LDLDrug PrescriptionsFatty Acids, MonounsaturatedFemaleFluvastatinFollow-Up StudiesHeptanoic AcidsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsIndolesLovastatinMaleMyocardial InfarctionOdds RatioPravastatinPyridinesPyrrolesRetrospective StudiesSurvival RateTreatment OutcomeConceptsAcute myocardial infarctionHydroxymethylglutaryl-CoA reductase inhibitorsStatin therapyMyocardial infarctionLower mortalityOlder personsReductase inhibitorsPrincipal discharge diagnosisAcute care hospitalsCause mortalityEligible patientsOlder patientsYounger patientsCare hospitalDischarge prescriptionsPrimary outcomeDischarge diagnosisHospital characteristicsEfficacy dataMedicare patientsMultivariable modelObservational studyPatientsStatinsDischarge statins
2001
Do Existing Databases Answer Clinical Questions about Geriatric Cardiovascular Disease and Stroke?
Cheitlin MD, Gerstenblith G, Hazzard WR, Pasternak R, Fried LP, Rich MW, Krumholz HM, Peterson E, Reves JG, McKay C, Saksena S, Shen WK, Akhtar M, Brass LM, Biller J. Do Existing Databases Answer Clinical Questions about Geriatric Cardiovascular Disease and Stroke? The American Journal Of Geriatric Cardiology 2001, 10: 207-223. PMID: 11455241, DOI: 10.1111/j.1076-7460.2003.00696.x.Peer-Reviewed Original ResearchConceptsCardiovascular diseaseYounger patientsChronic coronary artery diseaseExtrapolation of safetyRole of revascularizationChronic heart failurePatients 75 yearsRisk factor modificationCharacteristics of patientsCoronary artery diseaseAcute myocardial infarctionYears of ageCollaborative outcomes researchPrincipal investigatorGeriatric cardiologyValve surgeryArtery diseaseHeart failureCarotid endarterectomyFactor modificationMyocardial infarctionEfficacy dataCardiovascular conditionsClinical questionsAvailable safety