2022
Joint longitudinal trajectories of pain intensity and opioid prescription in veterans with back pain
Buta E, Gordon KS, Gueorguieva R, Becker WC, Heapy A, Bathulapalli H, Zeng Q, Redd D, Brandt C, Goulet J. Joint longitudinal trajectories of pain intensity and opioid prescription in veterans with back pain. Pharmacoepidemiology And Drug Safety 2022, 31: 1262-1271. PMID: 35996825, DOI: 10.1002/pds.5531.Peer-Reviewed Original ResearchConceptsBack painOpioid prescriptionsPain/Pain intensityRetrospective cohort studyTrajectories of painElectronic health record dataMental health diagnosesHealth record dataHigh opioidCohort studyClinical predictorsHigher oddsPainLatent class growth analysisOpioidsPain classesHealth diagnosisRecord dataVeteransLongitudinal trajectoriesPrescriptionOddsTrajectory classesDistinct patternsMilitary sexual trauma and incident hypertension: a 16-year cohort study of young and middle-aged men and women
Gaffey AE, Rosman L, Sico JJ, Haskell SG, Brandt CA, Bathulapalli H, Han L, Dziura J, Skanderson M, Burg MM. Military sexual trauma and incident hypertension: a 16-year cohort study of young and middle-aged men and women. Journal Of Hypertension 2022, 40: 2307-2315. PMID: 35983872, DOI: 10.1097/hjh.0000000000003267.Peer-Reviewed Original ResearchConceptsIncident hypertensionRisk factorsPsychiatric disordersMultivariate Cox proportional hazards modelVeterans Health Administration dataGreater riskCox proportional hazards modelTrauma-related psychiatric disordersMiddle-aged veteransCardiovascular risk factorsBaseline blood pressureElevated cardiovascular riskLarge prospective cohortHealth Administration dataMiddle-aged menProportional hazards modelSex-specific analysesPosttraumatic stress disorderMilitary sexual traumaCardiovascular riskCohort studyProspective cohortBlood pressureTreatment attenuatesCardiovascular impact
2021
Brief Report: Are Serious Falls Associated With Subsequent Fragility Fractures Among Veterans Living With HIV?
Womack JA, Murphy TE, Ramsey C, Bathulapalli H, Leo-Summers L, Smith AC, Bates J, Jarad S, Gill TM, Hsieh E, Rodriguez-Barradas MC, Tien PC, Yin MT, Brandt C, Justice AC. Brief Report: Are Serious Falls Associated With Subsequent Fragility Fractures Among Veterans Living With HIV? JAIDS Journal Of Acquired Immune Deficiency Syndromes 2021, 88: 192-196. PMID: 34506360, PMCID: PMC8513792, DOI: 10.1097/qai.0000000000002752.Peer-Reviewed Original ResearchConceptsSubsequent fragility fracturesFragility fracturesAntiretroviral therapySerious fallsRisk factorsVeterans Aging Cohort StudyAging Cohort StudyMultivariable logistic regressionUpper arm fracturesMiddle-aged populationYears of ageAlcohol use disorderCohort studyHip fractureVertebral fracturesArm fracturesInjury codesICD9 codesGeneral populationUse disordersLogistic regressionIntegrase inhibitorsOlder adultsRadiology reportsHIVPain intensity and pain medication prescription patterns in Veterans with heart failure and back pain
Cavanagh CE, Rosman L, Chui PW, DeRycke E, Bathulapalli H, Gandhi P, Bastian LA, Burg MM, Brandt C, Goulet JL. Pain intensity and pain medication prescription patterns in Veterans with heart failure and back pain. Heart & Lung 2021, 50: 770-774. PMID: 34225088, DOI: 10.1016/j.hrtlng.2021.04.016.Peer-Reviewed Original ResearchConceptsComorbid heart failureHeart failureBack painPain intensityMedication prescription patternsPain medication prescriptionsHigher likelihoodGabapentin prescriptionsNSAID prescriptionsPrescription patternsSevere painPain conditionsMedication prescriptionsClinical managementPainMusculoskeletal disordersDisorder cohortLower likelihoodVeteransFurther studiesPrescriptionFailureOpioidsCardiovascularCohort
2020
Serious Falls in Middle‐Aged Veterans: Development and Validation of a Predictive Risk Model
Womack JA, Murphy TE, Bathulapalli H, Smith A, Bates J, Jarad S, Redeker NS, Luther SL, Gill TM, Brandt CA, Justice AC. Serious Falls in Middle‐Aged Veterans: Development and Validation of a Predictive Risk Model. Journal Of The American Geriatrics Society 2020, 68: 2847-2854. PMID: 32860222, PMCID: PMC7744431, DOI: 10.1111/jgs.16773.Peer-Reviewed Original ResearchConceptsMiddle-aged veteransVeterans Health AdministrationOpioid useSerious fallsAlcohol Use Disorders Identification Test-Consumption scoresCategory-free net reclassification improvementIllicit substance use disordersMental health comorbiditiesPrescription opioid useMultivariable logistic regressionNet reclassification improvementSubstance use disordersQuality of lifeHazardous alcohol usePredictive risk modelChronic medicationsCohort studyHealth comorbiditiesNinth RevisionReclassification improvementGeriatric healthInjury codesHazardous alcoholInternational ClassificationUse disordersExploring supervised machine learning approaches to predicting Veterans Health Administration chiropractic service utilization
Coleman BC, Fodeh S, Lisi AJ, Goulet JL, Corcoran KL, Bathulapalli H, Brandt CA. Exploring supervised machine learning approaches to predicting Veterans Health Administration chiropractic service utilization. Chiropractic & Manual Therapies 2020, 28: 47. PMID: 32680545, PMCID: PMC7368704, DOI: 10.1186/s12998-020-00335-4.Peer-Reviewed Original ResearchConceptsSpinal pain conditionsService utilizationPain conditionsChiropractic careConservative interventionsChiropractic servicesVA chiropractic servicesRetrospective cohort studyHealthcare service utilizationHealthcare cost burdenLimited clinical utilityLower healthcare costsCohort entryCohort studyDiagnosis cohortPain statusPrimary outcomeChiropractic visitsClinical featuresUS adultsClinical utilityHealthcare costsDifferent clinical populationsVisitsClinical populations
2018
Variation in National Opioid Prescribing Patterns Following Surgery for Kidney Stones
Leapman MS, DeRycke E, Skanderson M, Becker WC, Makarov DV, Gross CP, Driscoll M, Motamedinia P, Bathulapalli H, Mattocks K, Brandt CA, Haskell S, Bastian LA. Variation in National Opioid Prescribing Patterns Following Surgery for Kidney Stones. Pain Medicine 2018, 19: s12-s18. PMID: 30203013, DOI: 10.1093/pm/pny125.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderWomen Veterans Cohort StudyOpioid prescribingOpioid prescriptionsSurgical treatmentKidney stonesSignificant public health problemOpioid Prescribing PatternsPostoperative opioid prescribingDiagnosis of PTSDPublic health problemExtracorporeal shockwave lithotripsyOpioid dosingPostoperative painPrescribing patternsCohort studyDose prescribedMedian ageSurgery typeMultivariable analysisOpioid misuseSurgical interventionMedian numberPercutaneous nephrolithotomyMultivariable regressionEvaluation of Complementary and Integrative Health Approaches Among US Veterans with Musculoskeletal Pain Using Propensity Score Methods
Han L, Goulet JL, Skanderson M, Bathulapalli H, Luther SL, Kerns RD, Brandt CA. Evaluation of Complementary and Integrative Health Approaches Among US Veterans with Musculoskeletal Pain Using Propensity Score Methods. Pain Medicine 2018, 20: 90-102. PMID: 29584926, PMCID: PMC6329442, DOI: 10.1093/pm/pny027.Peer-Reviewed Original ResearchConceptsIntegrative health approachesPS matchingCIH exposureMusculoskeletal painPropensity score methodsSelf-rated pain intensityHealth approachHigher pain intensity ratingsPain intensity outcomesChronic musculoskeletal painPain intensity ratingsIPTW modelsRetrospective cohortPain intensityChronic painClinical visitsInitial diagnosisChiropractic careUS veteransBaseline differencesTreatment weightingExposure groupPainScore methodTreatment effectiveness
2017
Sleep Disturbance Among HIV-Infected and Uninfected Veterans
Womack JA, Murphy TE, Bathulapalli H, Akgün KM, Gibert C, Kunisaki KM, Rimland D, Rodriguez-Barradas M, Yaggi H, Justice AC, Redeker NS. Sleep Disturbance Among HIV-Infected and Uninfected Veterans. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2017, 74: e117-e120. PMID: 27906767, PMCID: PMC5326673, DOI: 10.1097/qai.0000000000001264.Peer-Reviewed Original ResearchTrajectories of Sleep Disturbance Severity in HIV-Infected and Uninfected Veterans
Womack JA, Murphy TE, Bathulapalli H, Akgün KM, Gibert C, Kunisaki KM, Rodriguez-Barradas M, Yaggi HK, Justice AC, Redeker NS. Trajectories of Sleep Disturbance Severity in HIV-Infected and Uninfected Veterans. Journal Of The Association Of Nurses In AIDS Care 2017, 28: 431-437. PMID: 28389058, PMCID: PMC5442598, DOI: 10.1016/j.jana.2017.02.006.Peer-Reviewed Original Research
2016
Incidence of Mental Health Diagnoses in Veterans of Operations Iraqi Freedom, Enduring Freedom, and New Dawn, 2001-2014.
Ramsey C, Dziura J, Justice AC, Altalib HH, Bathulapalli H, Burg M, Decker S, Driscoll M, Goulet J, Haskell S, Kulas J, Wang KH, Mattocks K, Brandt C. Incidence of Mental Health Diagnoses in Veterans of Operations Iraqi Freedom, Enduring Freedom, and New Dawn, 2001-2014. American Journal Of Public Health 2016, 107: 329-335. PMID: 27997229, PMCID: PMC5227942, DOI: 10.2105/ajph.2016.303574.Peer-Reviewed Original ResearchConceptsMental health diagnosesMajor depressive disorderPosttraumatic stress disorderHealth diagnosisIncidence rateDrug use disorder diagnosisIncident posttraumatic stress disorderOperation Iraqi FreedomAge 18Veterans Health Administration electronic health recordsDisorder diagnosisIncident bipolar disorderHigh-risk groupSociodemographic risk factorsAlcohol use disorder diagnosisMental health conditionsEnduring FreedomIraqi FreedomRace/ethnicityElectronic health recordsIncident schizophreniaRisk factorsDepressive disorderAge 45MDD diagnosisStatistical Models for the Analysis of Zero-Inflated Pain Intensity Numeric Rating Scale Data
Goulet JL, Buta E, Bathulapalli H, Gueorguieva R, Brandt CA. Statistical Models for the Analysis of Zero-Inflated Pain Intensity Numeric Rating Scale Data. Journal Of Pain 2016, 18: 340-348. PMID: 27919777, DOI: 10.1016/j.jpain.2016.11.008.Peer-Reviewed Original ResearchConceptsStatistical modelStatistical methodsExcess of zerosAlternative statistical methodsFollowing statistical modelsNumeric rating scaleNRS scoresDiscrete valuesOrdinal dataLarge cohortLinear modelCumulative logit modelMusculoskeletal disordersRight-skewed distributionZerosObservational cross-sectional studyInterpretability of resultsMean NRS painPainful musculoskeletal disordersPredictor effectsVeterans Affairs (VA) carePain intensity dataCross-sectional studyNRS dataDiagnosis dateEstimating healthcare mobility in the Veterans Affairs Healthcare System
Wang KH, Goulet JL, Carroll CM, Skanderson M, Fodeh S, Erdos J, Womack JA, Abel EA, Bathulapalli H, Justice AC, Nunez-Smith M, Brandt CA. Estimating healthcare mobility in the Veterans Affairs Healthcare System. BMC Health Services Research 2016, 16: 609. PMID: 27769221, PMCID: PMC5075153, DOI: 10.1186/s12913-016-1841-4.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overDelivery of Health CareElectronic Health RecordsEmigration and ImmigrationFemaleHospitals, VeteransHumansMaleMental DisordersMiddle AgedPatient Acceptance of Health CareRetrospective StudiesUnited StatesUnited States Department of Veterans AffairsVeteransVeterans HealthYoung AdultConceptsHealthcare systemVeterans Health Administration electronic health recordsVeterans Affairs Healthcare SystemHealthcare mobilityRetrospective cohort studyHepatitis C virusOutcomes of careDifferent healthcare systemsDistinct healthcare systemsElectronic health recordsClinical characteristicsCohort studyHealthcare utilizationC virusSpecialty carePsychiatric disordersYounger veteransDisease preventionYounger agePopulation healthHealth recordsVeteransStatus changesCareYear periodIncrease in migraine diagnoses and guideline-concordant treatment in veterans, 2004–2012
Altalib H, Fenton B, Sico J, Goulet J, Bathulapalli H, Mohammad A, Kulas J, Driscoll M, Dziura J, Mattocks K, Kerns R, Brandt C, Haskell S. Increase in migraine diagnoses and guideline-concordant treatment in veterans, 2004–2012. Cephalalgia 2016, 37: 3-10. PMID: 26950804, DOI: 10.1177/0333102416631959.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnalgesicsFemaleGuideline AdherenceHumansMaleMiddle AgedMigraine DisordersVeteransConceptsBurden of migraineMigraine diagnosisVeterans Health Administration electronic health recordsGuideline-concordant treatmentGuideline-concordant careMigraine-specific medicationsICD-9 codesChi-square testHealth care systemNumber of veteransElectronic health recordsTriptan prescriptionMigraine preventionGuideline adherenceMigraine medicationsComorbid conditionsNational health care systemMigraine headacheMedicationsMigraineTime-series studyLogistic regressionCare systemPreventive medicineHealth administrators
2015
Chest pain syndromes are associated with high rates of recidivism and costs in young United States Veterans
Safdar B, Dziura J, Bathulapalli H, Leslie DL, Skanderson M, Brandt C, Haskell SG. Chest pain syndromes are associated with high rates of recidivism and costs in young United States Veterans. BMC Primary Care 2015, 16: 88. PMID: 26202799, PMCID: PMC4511555, DOI: 10.1186/s12875-015-0287-9.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseUnexplained chest painChest painUCP patientsCAD patientsArtery diseaseRisk factorsReturn visitsSpecific ICD-9 codesVeterans AffairsChest pain syndromeRecurrent chest painReference groupRetrospective cohort studyEvidence-based guidelinesICD-9 codesUnited States veteransDirect total costCAD cohortCause deathCardiac painPain syndromeCohort studyCox regressionEmergency department
2014
STI Diagnosis and HIV Testing Among OEF/OIF/OND Veterans
Goulet JL, Martinello RA, Bathulapalli H, Higgins D, Driscoll MA, Brandt CA, Womack JA. STI Diagnosis and HIV Testing Among OEF/OIF/OND Veterans. Medical Care 2014, 52: 1064-1067. PMID: 25334054, PMCID: PMC4232995, DOI: 10.1097/mlr.0000000000000253.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHIV testing ratesSTI diagnosisHIV testingTesting ratesPatient characteristicsHigher HIV testing ratesPrevious HIV test resultsVeterans Health Administration (VHA) servicesRoutine HIV testingVHA administrative dataHIV test resultsRelative risk regressionSubstance abuse disordersPositive test resultsOEF/OIF/OND veteransPosttraumatic stress disorderHIV testImmunodeficiency virusRisk regressionInfection diagnosisMAIN OUTCOMEAbuse disordersService veteransOlder ageSex Differences in Patient and Provider Response to Elevated Low-Density Lipoprotein Cholesterol
Haskell SG, Bathulapalli H, Pham T, Goulet J, Skanderson M, Driscoll M, Brandt C, Dziura J. Sex Differences in Patient and Provider Response to Elevated Low-Density Lipoprotein Cholesterol. Women's Health Issues 2014, 24: 575-580. PMID: 25213750, DOI: 10.1016/j.whi.2014.06.004.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnticholesteremic AgentsAttitude of Health PersonnelAttitude to HealthDyslipidemiasElectronic Health RecordsFemaleHealthcare DisparitiesHumansLipoproteins, LDLLogistic ModelsMaleMiddle AgedOdds RatioPractice Patterns, Physicians'Risk FactorsSex FactorsTreatment OutcomeUnited StatesConceptsCholesterol controlElevated LDLLow-density lipoprotein cholesterol controlElevated low-density lipoprotein cholesterolLow-density lipoprotein cholesterolProvider responsesAmerican Heart Association recommendationsLipid-lowering medicationsIschemic heart diseaseDiet/lifestyle modificationLifestyle modificationStatin therapyLipoprotein cholesterolPatient factorsPatient sexRisk womenClinical remindersHeart diseaseWomen patientsPatient responseTreatment goalsAssociation recommendationsLDL elevationsMedicationsWomen veteransPersistent Pain and Comorbidity Among Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn Veterans
Higgins DM, Kerns RD, Brandt CA, Haskell SG, Bathulapalli H, Gilliam W, Goulet JL. Persistent Pain and Comorbidity Among Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn Veterans. Pain Medicine 2014, 15: 782-790. PMID: 24548466, DOI: 10.1111/pme.12388.Peer-Reviewed Original ResearchMeSH KeywordsAdultAfghan Campaign 2001-Chronic PainComorbidityDepressive DisorderFemaleHumansIraq War, 2003-2011Logistic ModelsLongitudinal StudiesMaleMiddle AgedMultivariate AnalysisObesityPrevalenceStress Disorders, Post-TraumaticSubstance-Related DisordersUnited StatesUnited States Department of Veterans AffairsVeteransConceptsVeterans Health AdministrationTraumatic brain injuryPersistent painBody mass indexMental health conditionsChronic painOperation Enduring FreedomHealth conditionsElectronic medical record dataChronic pain conditionsPredictors of incidentMedical record dataLongitudinal clinical dataImportant clinical implicationsSubstance use disordersOEF/OIF/OND veteransPost-traumatic stress disorderArmy service membersLogistic regression modelsPain conditionsComorbid conditionsClinical evidenceMass indexBrain injuryClinical data
2011
A polymorphism in the leptin gene promoter is associated with anemia in patients with HIV disease
Vanasse GJ, Jeong JY, Tate J, Bathulapalli H, Anderson D, Steen H, Fleming M, Mattocks K, Telenti A, Fellay J, Justice AC, Berliner N. A polymorphism in the leptin gene promoter is associated with anemia in patients with HIV disease. Blood 2011, 118: 5401-5408. PMID: 21926355, PMCID: PMC3217345, DOI: 10.1182/blood-2011-06-362194.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyCombined antiretroviral therapyPrevalence of anemiaHIV diseaseSingle nucleotide polymorphismsModern combined antiretroviral therapyWorld Health Organization criteriaAging Cohort StudyA Single Nucleotide PolymorphismGene single nucleotide polymorphismsLeptin gene promoterHIV subjectsAntiretroviral therapyCohort studyHIV statusOrganization criteriaClinical dataIndependent cohortAnemiaHIVPatientsLeptin genePrevalenceDiseaseCandidate gene approachValidity of diagnostic codes and liver‐related laboratory abnormalities to identify hepatic decompensation events in the Veterans Aging Cohort Study
Re V, Lim JK, Goetz MB, Tate J, Bathulapalli H, Klein MB, Rimland D, Rodriguez‐Barradas M, Butt AA, Gibert CL, Brown ST, Kidwai F, Brandt C, Dorey‐Stein Z, Reddy KR, Justice AC. Validity of diagnostic codes and liver‐related laboratory abnormalities to identify hepatic decompensation events in the Veterans Aging Cohort Study. Pharmacoepidemiology And Drug Safety 2011, 20: 689-699. PMID: 21626605, PMCID: PMC3131229, DOI: 10.1002/pds.2148.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyHepatic decompensation eventsPositive predictive valueHigh positive predictive valueLaboratory abnormalitiesAging Cohort StudyDecompensation eventsDiagnostic codesCohort studyHepatic decompensationVariceal hemorrhageOutpatient diagnostic codesChronic liver diseaseSpontaneous bacterial peritonitisImpact of medicationLiver dysfunctionBacterial peritonitisLiver diseaseMedical recordsOutpatient codesPredictive valueNatural historyAbnormalitiesEpidemiologic researchPatients