Featured Publications
Formation of flavorant–propylene Glycol Adducts With Novel Toxicological Properties in Chemically Unstable E-Cigarette Liquids
Erythropel HC, Jabba SV, DeWinter TM, Mendizabal M, Anastas PT, Jordt SE, Zimmerman JB. Formation of flavorant–propylene Glycol Adducts With Novel Toxicological Properties in Chemically Unstable E-Cigarette Liquids. Nicotine & Tobacco Research 2018, 21: 1248-1258. PMID: 30335174, PMCID: PMC6698951, DOI: 10.1093/ntr/nty192.Peer-Reviewed Original ResearchConceptsFlavor aldehydesSolvent componentsNuclear magnetic resonance spectroscopyNovel chemical speciesReaction productsPhysiological aqueous solutionE-cigarette liquidsReactive chemical systemsToxicological propertiesCommercial e-liquidsMagnetic resonance spectroscopyE-liquidsAqueous mediaPropylene glycolAqueous solutionPotential toxicological effectsNew compoundsUltraviolet spectroscopyChemical speciesChemical reactionsGas chromatographyChemical systemsResonance spectroscopyToxicological effectsAldehydes
2017
The effect of sucralose on flavor sweetness in electronic cigarettes varies between delivery devices
Rosbrook K, Erythropel HC, DeWinter TM, Falinski M, O’Malley S, Krishnan-Sarin S, Anastas PT, Zimmerman JB, Green BG. The effect of sucralose on flavor sweetness in electronic cigarettes varies between delivery devices. PLOS ONE 2017, 12: e0185334. PMID: 28968411, PMCID: PMC5624589, DOI: 10.1371/journal.pone.0185334.Peer-Reviewed Original ResearchConceptsCommercial e-liquidsDelivery systemConcentrations of sucraloseE-liquid aerosolLC/MSE-liquidsVolatile flavor componentsLiquid delivery systemChemical compoundsChemical analysisArtificial sweetenersE-cigarette designFlavor additivesDelivery devicesVolatile constituentsFlavor componentsSweetener sucraloseVolatile chemicalsSweet aromaCartridge systemSufficient concentrationSucraloseEffect of sucralose