2024
Piwi regulates the usage of alternative transcription start sites in the Drosophila ovary
Chen J, Liu N, Qi H, Neuenkirchen N, Huang Y, Lin H. Piwi regulates the usage of alternative transcription start sites in the Drosophila ovary. Nucleic Acids Research 2024, gkae1160. PMID: 39657757, DOI: 10.1093/nar/gkae1160.Peer-Reviewed Original ResearchTranscription start siteTranscription start site usageFacilitates chromatin transcriptionDrosophila ovaryOvarian somatic cellsStart siteCap analysis of gene expression sequencingAlternative transcription start sitesSomatic cellsPol II initiationRNA polymerase IIAlternative transcription initiationRNA-binding proteinsCultured ovarian somatic cellsGene expression sequencingMRNA elongationPolymerase IIPol IITranscription initiationChromatin transcriptionTranscriptional regulationExpressed sequencesMutant ovariesPIWICap analysis
2011
A High-Resolution Whole-Genome Map of Key Chromatin Modifications in the Adult Drosophila melanogaster
Yin H, Sweeney S, Raha D, Snyder M, Lin H. A High-Resolution Whole-Genome Map of Key Chromatin Modifications in the Adult Drosophila melanogaster. PLOS Genetics 2011, 7: e1002380. PMID: 22194694, PMCID: PMC3240582, DOI: 10.1371/journal.pgen.1002380.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsChromatin Assembly and DisassemblyChromatin ImmunoprecipitationChromosomal Proteins, Non-HistoneChromosome MappingDrosophila melanogasterDrosophila ProteinsEpigenesis, GeneticEuchromatinGenome, InsectHeterochromatinHigh-Throughput Nucleotide SequencingHistonesRepetitive Sequences, Nucleic AcidRetroelementsRNA Polymerase IITranscription Initiation SiteConceptsHeterochromatin protein 1aChromatin modificationsStart siteChromatin modification landscapeKey chromatin modificationKey histone marksCell typesDrosophila cell typesRNA polymerase IIAdult Drosophila melanogasterTranscriptional start siteDiverse cell typesTranscription start siteFunctionality of genesHigh-Resolution WholeEuchromatic marksHistone codeHistone marksModification landscapeDrosophila melanogasterPolymerase IIGenome mapChromatin immunoprecipitationRegulatory sequencesSplicing junctions