2022
Benefits and harms of oral anticoagulants for atrial fibrillation in nursing home residents with advanced dementia
Ouellet GM, O'Leary JR, Leggett CG, Skinner J, Tinetti ME, Cohen AB. Benefits and harms of oral anticoagulants for atrial fibrillation in nursing home residents with advanced dementia. Journal Of The American Geriatrics Society 2022, 71: 561-568. PMID: 36310367, PMCID: PMC9957933, DOI: 10.1111/jgs.18108.Peer-Reviewed Original ResearchConceptsNursing home residentsAtrial fibrillationAdvanced dementiaHome residentsStroke riskLong-stay nursing home residentsMedicare Part D claimsDementia-related mortalityGuideline-recommended thresholdHarms of anticoagulationRetrospective cohort studyMultivariable survival analysisValvular heart diseaseRisk of deathPart D claimsMonths of lifeMinimum Data SetAnticoagulant discontinuationAnticoagulated individualsMean CHAVASc scoreCause mortalityMultivariable adjustmentOral anticoagulantsCohort studyThe association between beta‐blockers and outcomes in patients with heart failure and concurrent Alzheimer's disease and related dementias
Gilstrap L, Cohen A, Ouellet GM, Goyal P, Gladders B, Flint D, Skinner J. The association between beta‐blockers and outcomes in patients with heart failure and concurrent Alzheimer's disease and related dementias. Journal Of The American Geriatrics Society 2022, 71: 404-413. PMID: 36240493, DOI: 10.1111/jgs.18086.Peer-Reviewed Original ResearchConceptsHigh riskBB useHeart failureAlzheimer's diseaseLong-term mortality ratesConcurrent Alzheimer's diseaseBeta-blocker useReduced ejection fractionMedicare Part ARisk/benefitBB therapyEjection fractionContemporary patientsHFrEFHigh prevalenceSimilar riskMortality ratePatientsCognitive impairmentMortalityDiseaseADRDRiskTherapyOutcomes
2021
Presentation, Treatment, and Outcomes of Older Adults Hospitalized for Acute Myocardial Infarction According to Cognitive Status: The SILVER-AMI Study
Hajduk AM, Saczynski JS, Tsang S, Geda ME, Dodson JA, Ouellet GM, Goldberg RJ, Chaudhry SI. Presentation, Treatment, and Outcomes of Older Adults Hospitalized for Acute Myocardial Infarction According to Cognitive Status: The SILVER-AMI Study. The American Journal Of Medicine 2021, 134: 910-917. PMID: 33737057, PMCID: PMC8243828, DOI: 10.1016/j.amjmed.2021.03.003.Peer-Reviewed Original ResearchConceptsSevere cognitive impairmentAcute myocardial infarctionMyocardial infarctionCognitive impairmentOlder acute myocardial infarction patientsCognitive statusMultivariable-adjusted logistic regressionAcute myocardial infarction patientsOlder adultsRoutine cognitive screeningRisk of readmissionMedical record reviewRisk of deathPost-discharge periodMyocardial infarction patientsMyocardial infarction survivorsSILVER-AMI StudyComorbidity burdenHospital readmissionPoor outcomeRecord reviewFunctional statusInfarction patientsUnadjusted analysesInfarction survivors
2020
Risk Model for Decline in Activities of Daily Living Among Older Adults Hospitalized With Acute Myocardial Infarction: The SILVER‐AMI Study
Hajduk AM, Dodson JA, Murphy TE, Tsang S, Geda M, Ouellet GM, Gill TM, Brush JE, Chaudhry SI. Risk Model for Decline in Activities of Daily Living Among Older Adults Hospitalized With Acute Myocardial Infarction: The SILVER‐AMI Study. Journal Of The American Heart Association 2020, 9: e015555. PMID: 33000681, PMCID: PMC7792390, DOI: 10.1161/jaha.119.015555.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionDaily living declineSILVER-AMI StudyDaily livingOlder patientsMonths postdischargeMyocardial infarctionFunctional declineImportant patient-centered outcomesPoor long-term outcomesLonger hospital stayLong-term outcomesPatient-centered outcomesGeriatric impairmentsHospital stayAMI survivorsClinical variablesMean ageMedical recordsRisk factorsRestorative therapyPhysical activityAMI hospitalizationPsychosocial factorsUS hospitalsCombating Heightened Social Isolation of Nursing Home Elders: The Telephone Outreach in the COVID-19 Outbreak Program
van Dyck LI, Wilkins KM, Ouellet J, Ouellet GM, Conroy ML. Combating Heightened Social Isolation of Nursing Home Elders: The Telephone Outreach in the COVID-19 Outbreak Program. American Journal Of Geriatric Psychiatry 2020, 28: 989-992. PMID: 32593495, PMCID: PMC7274114, DOI: 10.1016/j.jagp.2020.05.026.Peer-Reviewed Original ResearchConceptsWeekly phone callsNursing home residentsElderly residentsTelephone outreachHome residentsNursing homesSocial isolationVulnerable patient populationNursing home eldersLocal nursing homeCOVID-19 pandemicPhone callsPatient populationOlder adultsStudent volunteersVolunteersInitial reportInitial successStudent interest groupsResidentsPandemicSocial connectednessPersistent needSocial wellbeing
2019
Challenges and strategies in patients’ health priorities-aligned decision-making for older adults with multiple chronic conditions
Tinetti M, Dindo L, Smith CD, Blaum C, Costello D, Ouellet G, Rosen J, Hernandez-Bigos K, Geda M, Naik A. Challenges and strategies in patients’ health priorities-aligned decision-making for older adults with multiple chronic conditions. PLOS ONE 2019, 14: e0218249. PMID: 31181117, PMCID: PMC6557523, DOI: 10.1371/journal.pone.0218249.Peer-Reviewed Original ResearchConceptsPatients' health prioritiesMultiple chronic conditionsHealth priorityChronic conditionsPatient prioritiesPatient Priorities CarePrimary care cliniciansCare of patientsCare cliniciansPrimary carePatient outcomesCardiology practicePatientsCare optionsCare PilotCliniciansOlder adultsSerial trialsCarePriority careImplementation teamQualitative studyMultiple conditionsAdditional settingsMultiplicity of problemsFunctional Outcomes After Hip Fracture in Independent Community‐Dwelling Patients
Ouellet JA, Ouellet GM, Romegialli AM, Hirsch M, Berardi L, Ramsey CM, Cooney LM, Walke LM. Functional Outcomes After Hip Fracture in Independent Community‐Dwelling Patients. Journal Of The American Geriatrics Society 2019, 67: 1386-1392. PMID: 30964203, PMCID: PMC6941577, DOI: 10.1111/jgs.15870.Peer-Reviewed Original ResearchConceptsNumber of medicationsHospital deliriumCare hoursADL disabilityHip fractureCommunity-dwelling adults 65Community-Dwelling PatientsNew ADL disabilityHip fracture surgeryRetrospective cohort studyDaily living (ADL) disabilityHip fracture patientsProportion of patientsCharacteristics of hospitalizationsIndependent older adultsChart reviewCohort studyFracture patientsFracture surgeryPatient chartsPoor outcomeFunctional outcomeAcademic hospitalOpiate useDelirium
2018
National Prescribing Trends for High‐Risk Anticholinergic Medications in Older Adults
Rhee TG, Choi YC, Ouellet GM, Ross JS. National Prescribing Trends for High‐Risk Anticholinergic Medications in Older Adults. Journal Of The American Geriatrics Society 2018, 66: 1382-1387. PMID: 29582410, PMCID: PMC6097908, DOI: 10.1111/jgs.15357.Peer-Reviewed Original ResearchConceptsNational Ambulatory Medical Care SurveyAnticholinergic prescriptionsPhysician specialtyDrug classesPrescribing trendsOffice-based outpatient visitsOffice-based physician visitsAmbulatory Medical Care SurveyMultivariable logistic regression analysisOlder adultsNational prescribing trendsCommon drug classesLogistic regression analysisCross-sectional analysisSpecific physician specialtiesAnticholinergic medicationsPhysician visitsOutpatient visitsQuality prescribingCare SurveyFemale sexStratified analysisSouthern geographic regionsGreater oddsTotal visits
2017
Prehospital Delay in Older Adults with Acute Myocardial Infarction: The ComprehenSIVe Evaluation of Risk Factors in Older Patients with Acute Myocardial Infarction Study
Ouellet GM, Geda M, Murphy TE, Tsang S, Tinetti ME, Chaudhry SI. Prehospital Delay in Older Adults with Acute Myocardial Infarction: The ComprehenSIVe Evaluation of Risk Factors in Older Patients with Acute Myocardial Infarction Study. Journal Of The American Geriatrics Society 2017, 65: 2391-2396. PMID: 29044463, PMCID: PMC5681402, DOI: 10.1111/jgs.15102.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionAcute Myocardial Infarction StudyMyocardial Infarction StudyPrehospital delayOlder adultsOlder patientsHeart failureMyocardial infarctionRisk factorsFuture public health effortsContemporary national cohortMedical record abstractionPublic health effortsCross-sectional analysisAntiischemic therapyHospital presentationIndex hospitalizationHospital delaySymptom durationDiabetes mellitusClinical presentationComorbid conditionsRecord abstractionAtypical symptomsNonwhite race
2015
Prostate Cancer in Elderly Men Screening, Active Surveillance, and Definitive Therapy
Roussel B, Ouellet GM, Mohile SG, Dale W. Prostate Cancer in Elderly Men Screening, Active Surveillance, and Definitive Therapy. Clinics In Geriatric Medicine 2015, 31: 615-629. PMID: 26476120, DOI: 10.1016/j.cger.2015.07.004.Peer-Reviewed Original Research
2012
Effect of Cardiac Resynchronization Therapy on the Risk of First and Recurrent Ventricular Tachyarrhythmic Events in MADIT-CRT
Ouellet G, Huang DT, Moss AJ, Hall WJ, Barsheshet A, McNitt S, Klein H, Zareba W, Goldenberg I. Effect of Cardiac Resynchronization Therapy on the Risk of First and Recurrent Ventricular Tachyarrhythmic Events in MADIT-CRT. Journal Of The American College Of Cardiology 2012, 60: 1809-1816. PMID: 23040580, DOI: 10.1016/j.jacc.2012.05.057.Peer-Reviewed Original ResearchConceptsLeft bundle branch blockVentricular tachyarrhythmic eventsNon-LBBB patientsFirst arrhythmic eventCardiac resynchronization therapyMADIT-CRTResynchronization therapyArrhythmic riskTachyarrhythmic eventsArrhythmic eventsSubsequent heart failureCRT-D therapyBundle branch blockCox proportional hazardsRisk of FirstHeart failureActive treatmentEfficacy analysisBranch blockPatientsProportional hazardsMultivariate analysisTherapyRegression modelingRisk
2009
Influence of Diabetes Mellitus on Outcome in Patients Over 40 Years of Age With the Long QT Syndrome
Ouellet G, Moss AJ, Jons C, McNitt S, Mullally J, Fugate T, Goldenberg I, Zareba W, Robinson JL, Registry I. Influence of Diabetes Mellitus on Outcome in Patients Over 40 Years of Age With the Long QT Syndrome. The American Journal Of Cardiology 2009, 105: 87-89. PMID: 20102896, PMCID: PMC2813216, DOI: 10.1016/j.amjcard.2009.08.657.Peer-Reviewed Original ResearchConceptsYears of ageFirst cardiac eventLong QT syndromeCardiac eventsQTc intervalRisk factorsAdult patientsDiabetes mellitusQT syndromeEnd pointIndependent mortality riskOral diabetic medicationsProlonged QTc intervalImpact of diabetesDevelopment of diabetesBeats/minInternational Long QT Syndrome RegistryCause mortalityDiabetic medicationsOlder patientsStudy populationVentricular repolarizationMortality riskHeart rateCox model