2001
B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function
Tamura H, Dong H, Zhu G, Sica G, Flies D, Tamada K, Chen L. B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function. Blood 2001, 97: 1809-1816. PMID: 11238124, DOI: 10.1182/blood.v97.6.1809.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntigens, CDB7-1 AntigenB7-2 AntigenB7-H1 AntigenBlood ProteinsCD28 AntigensCloning, MolecularCytokinesFemaleHumansInducible T-Cell Co-Stimulator LigandLigandsMembrane GlycoproteinsMiceMice, KnockoutMolecular Sequence DataPeptidesProteinsSequence AlignmentT-Lymphocytes, CytotoxicT-Lymphocytes, Helper-InducerConceptsT helper cell functionHuman B7-H1B7-H1T cell proliferationInducible costimulatorT cellsT-lymphocyte antigen-4Cytolytic T cell responsesT cell responsesCell functionGranulocyte-macrophage colony-stimulating factorP815 tumor cellsT cell growthColony-stimulating factorB7-like moleculeAllogeneic antigensLymphocyte responsesInterleukin-10Costimulatory pathwayAntigen-4IL-4Immunologic functionIL-2B7-1Cytokine secretion
2000
Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS
Wang S, Zhu G, Chapoval A, Dong H, Tamada K, Ni J, Chen L. Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS. Blood 2000, 96: 2808-2813. PMID: 11023515, DOI: 10.1182/blood.v96.8.2808.Peer-Reviewed Original ResearchMeSH KeywordsAbataceptAmino Acid SequenceAnimalsAntigens, CDAntigens, DifferentiationAntigens, Differentiation, T-LymphocyteCarrier ProteinsCD3 ComplexCell DivisionCHO CellsCloning, MolecularCricetinaeCricetulusCTLA-4 AntigenDendritic CellsDNA, ComplementaryGenes, ImmunoglobulinHumansImmunoconjugatesImmunoglobulin GInducible T-Cell Co-Stimulator LigandInducible T-Cell Co-Stimulator ProteinInterleukin-10Interleukin-2LigandsLymphocyte ActivationMiceMice, Inbred BALB CMolecular Sequence DataProtein Structure, TertiaryProteinsRecombinant Fusion ProteinsSequence AlignmentSequence Homology, Amino AcidT-LymphocytesTransfectionConceptsB7-H2T cellsMonocyte-derived immature dendritic cellsImmature dendritic cellsIL-10 productionSecretion of interleukinT cell proliferationB7-like moleculeT cell moleculesImmunoglobulin fusion proteinDendritic cellsCell surface expressionCD3 ligationSurface expressionChinese hamster ovary cellsCostimulationHamster ovary cellsCellsOvary cellsPutative ligandCTLA4IgInterleukinCD3Fusion proteinICOS