B7-H3: A costimulatory molecule for T cell activation and IFN-γ production
Chapoval A, Ni J, Lau J, Wilcox R, Flies D, Liu D, Dong H, Sica G, Zhu G, Tamada K, Chen L. B7-H3: A costimulatory molecule for T cell activation and IFN-γ production. Nature Immunology 2001, 2: 269-274. PMID: 11224528, DOI: 10.1038/85339.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAntigens, CDB7 AntigensB7-1 AntigenCells, CulturedCloning, MolecularCytokinesDendritic CellsHumansInterferon-gammaLymphocyte ActivationMolecular Sequence DataProtein IsoformsReceptors, ImmunologicSequence Homology, Amino AcidT-LymphocytesT-Lymphocytes, CytotoxicTranscription, GeneticTumor Cells, CulturedConceptsIFN-γ productionDendritic cellsB7-H3 proteinT cellsPhorbol myristate acetateB7-H3Inducible costimulatorT-lymphocyte antigen-4Cell-mediated immune responsesPeripheral blood mononuclear cellsAllogeneic T cellsBlood mononuclear cellsInterferon-γ ProductionB7 homolog 3Cytotoxic T cellsB7-H3 mRNAB7 family membersActivated T cellsT cell activationT cell receptor signalingPD-1Cell receptor signalingCostimulatory pathwayInflammatory cytokinesAntigen-4