2009
Frequency, prognosis and surgical treatment of structural abnormalities seen with magnetic resonance imaging in childhood epilepsy
Berg AT, Mathern GW, Bronen RA, Fulbright RK, DiMario F, Testa FM, Levy SR. Frequency, prognosis and surgical treatment of structural abnormalities seen with magnetic resonance imaging in childhood epilepsy. Brain 2009, 132: 2785-2797. PMID: 19638447, PMCID: PMC2759335, DOI: 10.1093/brain/awp187.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge of OnsetAnticonvulsantsBrainChildChild, PreschoolCognitionCohort StudiesDrug ResistanceEpilepsyFemaleFunctional LateralityHumansImage Processing, Computer-AssistedInfantLogistic ModelsMagnetic Resonance ImagingMaleNeurologic ExaminationNeuropsychological TestsNeurosurgical ProceduresPrognosisSclerosisTomography, X-Ray ComputedConceptsMagnetic resonance imagingPositive MRI scansEpilepsy patientsMRI scansEpilepsy syndromesEpilepsy evaluationSurgical proceduresMultiple logistic regression analysisUse of MRIComprehensive epilepsy evaluationNon-idiopathic patientsPediatric epilepsy patientsComprehensive Epilepsy CenterPositive MRI findingsCommunity-based cohortNormal neurological examPre-surgical evaluationLogistic regression analysisIdiopathic epilepsy syndromesFrequency of lesionsClinical factorsMRI abnormalitiesMRI findingsNeurological examSurgical treatment
2003
Hypothalamic hamartomas: seven cases and review of the literature
Nguyen D, Singh S, Zaatreh M, Novotny E, Levy S, Testa F, Spencer SS. Hypothalamic hamartomas: seven cases and review of the literature. Epilepsy & Behavior 2003, 4: 246-258. PMID: 12791326, DOI: 10.1016/s1525-5050(03)00086-6.Peer-Reviewed Original ResearchConceptsSessile lesionsPrecocious pubertyDifferent surgical optionsGamma Knife surgeryRare developmental lesionIntrinsic epileptogenicityGelastic seizuresGelastic epilepsySeizure typesPartial resectionSurgical optionsHypothalamic hamartomaOpen surgeryTranscallosal approachClinical aspectsSubtemporal approachIntraventricular componentDevelopmental lesionsCognitive declineLesionsAvailable evidenceResectionSurgerySeizuresSubsequent development