2014
Complete remission of childhood-onset epilepsy: stability and prediction over two decades
Berg AT, Rychlik K, Levy SR, Testa FM. Complete remission of childhood-onset epilepsy: stability and prediction over two decades. Brain 2014, 137: 3213-3222. PMID: 25338950, PMCID: PMC4240301, DOI: 10.1093/brain/awu294.Peer-Reviewed Original ResearchConceptsComplete remissionSeizure resolutionSeizure outcomeInitial diagnosisChildhood epilepsyLast contactCourse of epilepsyChildhood-onset epilepsySelf-limited epilepsy syndromeProportional hazards modelProspective cohortBaseline factorsRelapse rateLate remissionEpilepsy syndromesComplete resolutionRemissionHazards modelPredictive valueEpilepsyLogistic regressionConnecticut StudyDiagnosisFurther treatmentDevelopmental problems
2009
Remission of epilepsy after two drug failures in children: A prospective study
Berg AT, Levy SR, Testa FM, D'Souza R. Remission of epilepsy after two drug failures in children: A prospective study. Annals Of Neurology 2009, 65: 510-519. PMID: 19475671, PMCID: PMC2818062, DOI: 10.1002/ana.21642.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnticonvulsantsChildChild, PreschoolChi-Square DistributionDrug Therapy, CombinationEpilepsyFemaleFollow-Up StudiesHumansInfantInfant, NewbornMalePredictive Value of TestsProbabilityProportional Hazards ModelsProspective StudiesRecurrenceRetrospective StudiesTime FactorsTreatment FailureConceptsDrug failureRemission of epilepsyAggressive treatmentSeizure frequencyPrognostic factorsThird drugInitial diagnosisSymptomatic causesProspective studyProportional hazards techniquesIdiopathic epilepsyAppropriate drugsRemissionSecond drugLast contactOnly correlateEpilepsyDrugsChildrenFailurePredictorsRobust predictorPatientsRelapseTherapy
2004
Mortality in Childhood-Onset Epilepsy
Berg AT, Shinnar S, Testa FM, Levy SR, Smith SN, Beckerman B. Mortality in Childhood-Onset Epilepsy. JAMA Pediatrics 2004, 158: 1147-1152. PMID: 15583099, DOI: 10.1001/archpedi.158.12.1147.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolConnecticutEpilepsyFemaleHumansInfantMalePredictive Value of TestsProspective StudiesRisk FactorsSeverity of Illness IndexConceptsStandardized mortality ratioRisk of deathMortality ratioMultivariable analysisOverall standardized mortality ratioProspective community-based cohortCox proportional hazards modelSevere underlying conditionsPredictors of deathChildhood-onset epilepsyCommunity-based cohortOccurrence of seizuresProportional hazards modelPoint of diagnosisCrude death rateNonsymptomatic epilepsySymptomatic etiologySymptomatic epilepsyUnderlying disorderUnderlying conditionExcess mortalityMost deathsOutcome measuresHazards modelChi2 test