2018
Evolution and course of early life developmental encephalopathic epilepsies: Focus on Lennox‐Gastaut syndrome
Berg AT, Levy SR, Testa FM. Evolution and course of early life developmental encephalopathic epilepsies: Focus on Lennox‐Gastaut syndrome. Epilepsia 2018, 59: 2096-2105. PMID: 30255934, PMCID: PMC6215498, DOI: 10.1111/epi.14569.Peer-Reviewed Original ResearchConceptsLennox-Gastaut syndromeInitial presentationMedian onset ageChi-square testRefractory seizuresCentral reviewEpilepsy syndromesInfantile spasmsEncephalopathic epilepsyMedical recordsOnset ageEarly deathEpilepsySyndromeCognitive outcomesConnecticut StudyLongitudinal studyT-testSeizuresChildrenPresentationSpasmStatistical analysisYearsMortality
2014
Complete remission of childhood-onset epilepsy: stability and prediction over two decades
Berg AT, Rychlik K, Levy SR, Testa FM. Complete remission of childhood-onset epilepsy: stability and prediction over two decades. Brain 2014, 137: 3213-3222. PMID: 25338950, PMCID: PMC4240301, DOI: 10.1093/brain/awu294.Peer-Reviewed Original ResearchConceptsComplete remissionSeizure resolutionSeizure outcomeInitial diagnosisChildhood epilepsyLast contactCourse of epilepsyChildhood-onset epilepsySelf-limited epilepsy syndromeProportional hazards modelProspective cohortBaseline factorsRelapse rateLate remissionEpilepsy syndromesComplete resolutionRemissionHazards modelPredictive valueEpilepsyLogistic regressionConnecticut StudyDiagnosisFurther treatmentDevelopmental problems
2009
Frequency, prognosis and surgical treatment of structural abnormalities seen with magnetic resonance imaging in childhood epilepsy
Berg AT, Mathern GW, Bronen RA, Fulbright RK, DiMario F, Testa FM, Levy SR. Frequency, prognosis and surgical treatment of structural abnormalities seen with magnetic resonance imaging in childhood epilepsy. Brain 2009, 132: 2785-2797. PMID: 19638447, PMCID: PMC2759335, DOI: 10.1093/brain/awp187.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge of OnsetAnticonvulsantsBrainChildChild, PreschoolCognitionCohort StudiesDrug ResistanceEpilepsyFemaleFunctional LateralityHumansImage Processing, Computer-AssistedInfantLogistic ModelsMagnetic Resonance ImagingMaleNeurologic ExaminationNeuropsychological TestsNeurosurgical ProceduresPrognosisSclerosisTomography, X-Ray ComputedConceptsMagnetic resonance imagingPositive MRI scansEpilepsy patientsMRI scansEpilepsy syndromesEpilepsy evaluationSurgical proceduresMultiple logistic regression analysisUse of MRIComprehensive epilepsy evaluationNon-idiopathic patientsPediatric epilepsy patientsComprehensive Epilepsy CenterPositive MRI findingsCommunity-based cohortNormal neurological examPre-surgical evaluationLogistic regression analysisIdiopathic epilepsy syndromesFrequency of lesionsClinical factorsMRI abnormalitiesMRI findingsNeurological examSurgical treatment
2006
How long does it take for epilepsy to become intractable? A prospective investigation
Berg AT, Vickrey BG, Testa FM, Levy SR, Shinnar S, DiMario F, Smith S. How long does it take for epilepsy to become intractable? A prospective investigation. Annals Of Neurology 2006, 60: 73-79. PMID: 16685695, DOI: 10.1002/ana.20852.Peer-Reviewed Original ResearchConceptsEarly remission periodSeizures/monthCatastrophic epilepsyFurther remissionTreatable epilepsyProspective cohortRemission periodEpilepsy syndromesIntractable epilepsyProspective InvestigationFocal epilepsyLast contactEpilepsyEpilepsy diagnosisRemissionSyndromeMore yearsChildrenMonthsDrugsYearsSurgerySeizuresReferralCohort
2004
Modeling remission and relapse in pediatric epilepsy: application of a Markov process
Berg AT, Lin J, Ebrahimi N, Testa FM, Levy SR, Shinnar S. Modeling remission and relapse in pediatric epilepsy: application of a Markov process. Epilepsy Research 2004, 60: 31-40. PMID: 15279868, DOI: 10.1016/j.eplepsyres.2004.05.002.Peer-Reviewed Original ResearchConceptsPartial epilepsyStandard survival techniquesEpilepsy syndromesProspective community-based studyCryptogenic partial epilepsySymptomatic partial epilepsyCommunity-based studyIdiopathic partial epilepsyTerms of patientTerminal remissionThird remissionSecond remissionSubsequent remissionSecond relapseSeizure outcomeInitial diagnosisPediatric epilepsyEpileptic encephalopathySurvival techniquesRelapse outcomesRemissionSyndrome groupRelapseEpilepsyRemission episodes