Hemodialysis and biotransformation of erythrocyte epoxy fatty acids in peripheral tissue
Liu T, Dogan I, Rothe M, Kunz J, Knauf F, Gollasch M, Luft F, Gollasch B. Hemodialysis and biotransformation of erythrocyte epoxy fatty acids in peripheral tissue. Prostaglandins Leukotrienes And Essential Fatty Acids 2022, 181: 102453. PMID: 35633593, DOI: 10.1016/j.plefa.2022.102453.Peer-Reviewed Original ResearchConceptsRed blood cellsHD treatmentHemodialysis treatmentEnd-stage renal disease patientsHydroxyeicosatetraenoic acidHydroxyeicosapentaenoic acidSingle hemodialysis treatmentChronic kidney diseaseRenal disease patientsRenal replacement therapyFatty acid statusVenous blood samplesHydroxydocosahexaenoic acidEpoxy fatty acidsCause of mortalityLOX pathwayRenal failureFatty acidsKidney diseaseDisease patientsVenous bloodCardiovascular functionAcid statusArteriovenous differenceCardiovascular diseaseHemodialysis and Plasma Oxylipin Biotransformation in Peripheral Tissue
Liu T, Dogan I, Rothe M, Kunz J, Knauf F, Gollasch M, Luft F, Gollasch B. Hemodialysis and Plasma Oxylipin Biotransformation in Peripheral Tissue. Metabolites 2022, 12: 34. PMID: 35050156, PMCID: PMC8781597, DOI: 10.3390/metabo12010034.Peer-Reviewed Original ResearchArteriovenous differenceEnd-stage renal disease patientsCytochrome P450Renal disease patientsVenous blood samplesArterial blood plasmaImpact of HDSoluble epoxide hydrolase activityVenous blood streamCardiovascular morbidityHemodialysis patientsDisease patientsVenous bloodHD treatmentUpper extremityPeripheral tissuesBlood samplesLipid mediatorsUpper limbEpoxide hydrolase activityBlood streamPatientsMetabolite levelsDeleterious effectsBlood plasma