2019
Obsessive–compulsive disorder
Stein D, Costa D, Lochner C, Miguel E, Reddy Y, Shavitt R, van den Heuvel O, Simpson H. Obsessive–compulsive disorder. Nature Reviews Disease Primers 2019, 5: 52. PMID: 31371720, PMCID: PMC7370844, DOI: 10.1038/s41572-019-0102-3.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderSimilar symptom dimensionsExtent of comorbiditySpecific brain circuitsGroup of conditionsTranslational Neuroscience ApproachCognitive behavioral therapyIntractable symptomsReuptake inhibitorsClinical outcomesChronic conditionsGlobal disabilityEffective treatmentInternational ClassificationGlobal mental healthRelated disordersMental disordersNeuropsychiatric disordersRepetitive stereotyped behaviorsBrain circuitsIndividualized assessmentMental healthNeurobiological mechanismsStatistical ManualHomogenous disorder
2011
A Double-Blind, Randomized, Controlled Trial of Fluoxetine Plus Quetiapine or Clomipramine Versus Fluoxetine Plus Placebo for Obsessive-Compulsive Disorder
Diniz J, Shavitt R, Fossaluza V, Koran L, de Bragança Pereira C, Miguel E. A Double-Blind, Randomized, Controlled Trial of Fluoxetine Plus Quetiapine or Clomipramine Versus Fluoxetine Plus Placebo for Obsessive-Compulsive Disorder. Journal Of Clinical Psychopharmacology 2011, 31: 763-768. PMID: 22020357, DOI: 10.1097/jcp.0b013e3182367aee.Peer-Reviewed Original ResearchConceptsY-BOCS scoresFluoxetine groupTreatment regimenSelective serotonin reuptake inhibitorsPlacebo-controlled trialSevere adverse eventsSerotonin reuptake inhibitorsMain outcome measuresObsessive-compulsive disorder patientsCompulsive Scale scoresYale-Brown ObsessiveFluoxetine monotherapyAdverse eventsReuptake inhibitorsObsessive-compulsive disorderPrimary diagnosisOutcome measuresDisorder patientsScale scoreFluoxetineMental disordersQuetiapinePatientsStatistical ManualClomipramineSkin picking and trichotillomania in adults with obsessive-compulsive disorder
Lovato L, Ferrão Y, Stein D, Shavitt R, Fontenelle L, Vivan A, Miguel E, Cordioli A. Skin picking and trichotillomania in adults with obsessive-compulsive disorder. Comprehensive Psychiatry 2011, 53: 562-568. PMID: 22014580, DOI: 10.1016/j.comppsych.2011.06.008.Peer-Reviewed Original ResearchConceptsPathologic skin pickingObsessive-compulsive disorderSkin pickingFourth Edition Axis IEdition Axis IStructured Clinical InterviewLogistic regression analysisComorbid body dysmorphic disorderBody dysmorphic disorderClinical characteristicsSuch comorbiditiesPrimary diagnosisAxis IClinical InterviewSpecific subgroupsMental disordersDysmorphic disorderStatistical ManualTrichotillomaniaDisordersCompulsive symptomsPatientsRegression analysisDiagnosisHigh levels
2009
Higher prevalence of obsessive–compulsive spectrum disorders in rheumatic fever
de Alvarenga P, Floresi A, Torres A, Hounie A, Fossaluza V, Gentil A, Pereira C, Miguel E. Higher prevalence of obsessive–compulsive spectrum disorders in rheumatic fever. General Hospital Psychiatry 2009, 31: 178-180. PMID: 19269540, DOI: 10.1016/j.genhosppsych.2008.11.003.Peer-Reviewed Original ResearchConceptsRheumatic feverObsessive-compulsive spectrum disordersHigh prevalencePrevious historyPsychiatric outpatientsAnalytical cross-sectional studyConsecutive psychiatric outpatientsCross-sectional studySubclinical obsessive-compulsive disorderObsessive-compulsive disorderPositive historySpectrum disorderPsychiatric diagnosisMental disordersRelated disordersSenior psychiatristsObsessive-compulsive symptomsStatistical ManualDisordersPrevalencePrivate practiceFeverOutpatientsFourth EditionSuch history
2006
Clinical features associated with treatment response in obsessive-compulsive disorder
Shavitt R, Belotto C, Curi M, Hounie A, Rosário-Campos M, Diniz J, Ferrão Y, Pato M, Miguel E. Clinical features associated with treatment response in obsessive-compulsive disorder. Comprehensive Psychiatry 2006, 47: 276-281. PMID: 16769302, DOI: 10.1016/j.comppsych.2005.09.001.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderClinical featuresPharmacological treatmentTreatment responseEarly onsetConsecutive adult patientsFourth Edition criteriaSensory phenomenaEarly-onset obsessive-compulsive disorderYale-Brown ObsessiveOral clomipramineClomipramine treatmentAdult patientsPoor prognosisPoor responseSao Paulo SchoolDisorders ClinicTic disordersEdition criteriaScore decreaseFavorable responseLinear regression analysisMental disordersStatistical ManualDisorders