2019
Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment
Ren C, Yuan Q, Braun M, Zhang X, Petri B, Zhang J, Kim D, Guez-Haddad J, Xue W, Pan W, Fan R, Kubes P, Sun Z, Opatowsky Y, Polleux F, Karatekin E, Tang W, Wu D. Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment. Developmental Cell 2019, 49: 206-219.e7. PMID: 30930167, PMCID: PMC6482112, DOI: 10.1016/j.devcel.2019.02.023.Peer-Reviewed Original ResearchActinsAnimalsCell AdhesionCell MembraneCell MovementCell PolarityCell-Matrix JunctionsCytoskeletonEndotheliumFemaleGTPase-Activating ProteinsHEK293 CellsHumansLeukocytesMaleMiceMice, Inbred C57BLMice, KnockoutMinor Histocompatibility AntigensMyosin Light ChainsNeutrophilsPhosphatidylinositol PhosphatesPhosphorylationPhosphotransferases (Alcohol Group Acceptor)Signal Transduction
2004
The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging
Zecca L, Stroppolo A, Gatti A, Tampellini D, Toscani M, Gallorini M, Giaveri G, Arosio P, Santambrogio P, Fariello R, Karatekin E, Kleinman M, Turro N, Hornykiewicz O, Zucca F. The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging. Proceedings Of The National Academy Of Sciences Of The United States Of America 2004, 101: 9843-9848. PMID: 15210960, PMCID: PMC470762, DOI: 10.1073/pnas.0403495101.Peer-Reviewed Original ResearchConceptsSubstantia nigraLocus coeruleusLC neuronsNeuronal vulnerabilityParkinson's diseaseCopper/zinc SODZinc SODCompacta neuronsParkinsonian syndromesBrainstem nucleiManganese superoxide dismutaseGlial cellsMajor molecular formCeruloplasmin levelsNormal subjectsRelated disordersRole of ironLight chain ferritinNeuronsDiseaseManganese SODFerritinNeuromelaninCoeruleusNM concentrations