2019
Decreases in Blood Pressure During Thrombectomy Are Associated With Larger Infarct Volumes and Worse Functional Outcome
Petersen NH, Ortega-Gutierrez S, Wang A, Lopez GV, Strander S, Kodali S, Silverman A, Zheng-Lin B, Dandapat S, Sansing LH, Schindler JL, Falcone GJ, Gilmore EJ, Amin H, Cord B, Hebert RM, Matouk C, Sheth KN. Decreases in Blood Pressure During Thrombectomy Are Associated With Larger Infarct Volumes and Worse Functional Outcome. Stroke 2019, 50: 1797-1804. PMID: 31159701, PMCID: PMC6787912, DOI: 10.1161/strokeaha.118.024286.Peer-Reviewed Original ResearchConceptsFinal infarct volumeWorse functional outcomeInfarct volumeEndovascular thrombectomyFunctional outcomeOcclusion strokeCerebral infarction 2b/3 reperfusionPressure reductionLarge vessel intracranial occlusionsGreater infarct growthBlood pressure reductionComprehensive stroke centerPercent of patientsBlood pressure managementLarger infarct volumesModified Rankin ScaleRankin Scale scoreMultivariable logistic regressionRelative hypotensionSustained hypotensionInfarct progressionNinety patientsInfarct growthIschemic penumbraIschemic stroke
2016
Interrater Agreement for Consensus Definitions of Delayed Ischemic Events After Aneurysmal Subarachnoid Hemorrhage
Zafar SF, Westover MB, Gaspard N, Gilmore EJ, Foreman BP, O'Connor KL, Rosenthal ES. Interrater Agreement for Consensus Definitions of Delayed Ischemic Events After Aneurysmal Subarachnoid Hemorrhage. Journal Of Clinical Neurophysiology 2016, 33: 235-240. PMID: 27258447, PMCID: PMC4894325, DOI: 10.1097/wnp.0000000000000276.Peer-Reviewed Original ResearchConceptsDelayed ischemic eventsCerebral infarctionNeurologic declineSubarachnoid hemorrhageConsensus definitionIschemic eventsCerebral ischemiaClinical trialsInterrater agreementPerfect overall agreementRadiographic cerebral infarctionPercent of patientsAneurysmal subarachnoid hemorrhageFuture large-scale studiesSuccessful clinical trialsMotor scoresMotor declineOutcome studiesInfarctionIschemiaType 1HemorrhageCT imagingLarge-scale studiesMRI techniques