2020
Risk of Worse Outcome in Stroke Patients with High Blood Pressure Variability After Endovascular Thrombectomy May Be Amplified by Impaired Cerebral Autoregulation (4457)
Nguyen C, Silverman A, Wang A, Kodali S, Strander S, Kimmel A, Peshwe K, de Havenon A, Gilmore E, Sansing L, Schindler J, Matouk C, Sheth K, Petersen N. Risk of Worse Outcome in Stroke Patients with High Blood Pressure Variability After Endovascular Thrombectomy May Be Amplified by Impaired Cerebral Autoregulation (4457). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.4457.Peer-Reviewed Original Research
2019
Deviation From Personalized Blood Pressure Targets Is Associated With Worse Outcome After Subarachnoid Hemorrhage
Silverman A, Kodali S, Strander S, Gilmore EJ, Kimmel A, Wang A, Cord B, Falcone G, Hebert R, Matouk C, Sheth KN, Petersen NH. Deviation From Personalized Blood Pressure Targets Is Associated With Worse Outcome After Subarachnoid Hemorrhage. Stroke 2019, 50: 2729-2737. PMID: 31495332, PMCID: PMC6756936, DOI: 10.1161/strokeaha.119.026282.Peer-Reviewed Original ResearchConceptsLimits of autoregulationAneurysmal subarachnoid hemorrhageSubarachnoid hemorrhageFunctional outcomeArterial pressureIntracranial pressureBP targetsWorse outcomesPercent timeBlood pressure targetsBlood pressure managementMean arterial pressureModified Rankin ScalePotential neuroprotective strategiesWorse functional outcomePoor functional outcomeCerebral blood flowMultivariate logistic regressionTotal monitoring periodAutoregulatory indexPressure targetsCerebral ischemiaNeuroprotective strategiesRankin ScaleCerebral autoregulation
2018
T62. Bilateral independent periodic discharges are associated with electrographic seizures and poor outcome: A case-control study
Osman G, Rahangdale R, Britton J, Gilmore E, Haider H, Hantus S, Herlopian A, Hocker S, Lee J, Legros B, Punia V, Rampal N, Szaflarski J, Wallace A, Westover M, Hirsch L, Gaspard N. T62. Bilateral independent periodic discharges are associated with electrographic seizures and poor outcome: A case-control study. Clinical Neurophysiology 2018, 129: e25-e26. DOI: 10.1016/j.clinph.2018.04.063.Peer-Reviewed Original ResearchBilateral independent periodic dischargesCase-control studyRetrospective case-control studyElectrographic seizuresBrain injuryPeriodic dischargesPoor outcomePD groupHospital mortality rateAcute brain injuryAnoxic brain injuryCNS infectionsFrequent etiologyLPD groupHemorrhagic strokeClinical correlatesWorse outcomesLevel of alertnessHigh riskBetter outcomesMortality rateControl groupMultivariate analysisSeizuresEEG patterns
2016
Status Epilepticus
Gilmore E, Nourollahzadeh E. Status Epilepticus. 2016, 23-33. DOI: 10.1007/978-3-319-33341-0_3.Peer-Reviewed Original ResearchManagement of seizuresStatus epilepticusSurgical intensive care unitLarge prospective epidemiologic studiesCommon neurological emergencyICU-related complicationsProspective epidemiologic studiesIntensive care unitOvert clinical manifestationsContinuous EEG monitoringMajority of seizuresNeurologic sequelaeCritical illnessSurgical ICUIll patientsSubstantial morbidityCare unitNeurological emergencyClinical manifestationsEarly recognitionMental statusWorse outcomesEpilepticusIctal activityEpidemiologic studies
2015
Clinical Correlates and Prognostic Significance of Lateralized Periodic Discharges in Patients Without Acute or Progressive Brain Injury
Sainju RK, Manganas LN, Gilmore EJ, Petroff OA, Rampal N, Hirsch LJ, Gaspard N. Clinical Correlates and Prognostic Significance of Lateralized Periodic Discharges in Patients Without Acute or Progressive Brain Injury. Journal Of Clinical Neurophysiology 2015, 32: 495-500. PMID: 26200591, DOI: 10.1097/wnp.0000000000000206.Peer-Reviewed Original ResearchConceptsProgressive brain injuryAcute brain injuryBrain injuryAbnormal consciousnessPeriodic dischargesClinical correlatesFunctional declineLateralized periodic dischargesRemote brain injuryOutcomes of patientsCase-control studyContinuous EEG monitoringHistory of epilepsyRadiologic evidenceHospital dischargeStatus epilepticusWorse prognosisAcute injuryPrognostic significanceWorse outcomesEEG monitoringMultivariate analysisInjuryPatientsLower likelihood