2024
Guidelines for Seizure Prophylaxis in Adults Hospitalized with Moderate–Severe Traumatic Brain Injury: A Clinical Practice Guideline for Health Care Professionals from the Neurocritical Care Society
Frontera J, Gilmore E, Johnson E, Olson D, Rayi A, Tesoro E, Ullman J, Yuan Y, Zafar S, Rowe S. Guidelines for Seizure Prophylaxis in Adults Hospitalized with Moderate–Severe Traumatic Brain Injury: A Clinical Practice Guideline for Health Care Professionals from the Neurocritical Care Society. Neurocritical Care 2024, 40: 819-844. PMID: 38316735, DOI: 10.1007/s12028-023-01907-x.Peer-Reviewed Original ResearchModerate-severe TBITraumatic brain injuryGrading of recommendations assessmentAntiseizure medicationsResultsThe initial literature searchAdverse eventsHealth care professionalsBrain injuryClinical practice guidelinesMeta-analysis of articlesEffects of antiseizure medicationsEarly seizuresLate seizuresCare professionalsCognitive outcomesRecommendations AssessmentDuration of prophylaxisPractice guidelinesSystematic reviewProphylactic antiseizure medicationPICO 1Meta-analysisLiterature searchFunctional outcomesGrading criteria
2015
Acute brain failure in severe sepsis: a prospective study in the medical intensive care unit utilizing continuous EEG monitoring
Gilmore EJ, Gaspard N, Choi HA, Cohen E, Burkart KM, Chong DH, Claassen J, Hirsch LJ. Acute brain failure in severe sepsis: a prospective study in the medical intensive care unit utilizing continuous EEG monitoring. Intensive Care Medicine 2015, 41: 686-694. PMID: 25763756, DOI: 10.1007/s00134-015-3709-1.Peer-Reviewed Original ResearchConceptsNonconvulsive seizuresSevere sepsisEEG reactivityPeriodic dischargesLate seizuresSOFA scoreAPACHE IIFunctional outcomeContinuous sedationHigh riskLower riskMedical intensive care unitLong-term cognitive outcomesPresence of sedationAPACHE II scoreGood functional outcomeNonconvulsive status epilepticusIntensive care unitContinuous EEG monitoringAcute brain failureAcademic medical centerNew epilepsyII scoreClinical seizuresMedical ICU