2024
Impact of electronic health record updates and changes on the delivery and monitoring of interventions in embedded pragmatic clinical trials
Marsolo K, Cheville A, Melnick E, Jarvik J, Simon G, Sluka K, Crofford L, Staman K, Richesson R, Schlaeger J, Curtis L. Impact of electronic health record updates and changes on the delivery and monitoring of interventions in embedded pragmatic clinical trials. Contemporary Clinical Trials 2024, 148: 107744. PMID: 39561918, DOI: 10.1016/j.cct.2024.107744.Peer-Reviewed Original ResearchElectronic health record systemsElectronic health recordsPragmatic clinical trialsElectronic health record platformsDelivery of interventionsHealth recordsTrial interventionMonitoring of interventionsRecord updatesStudy teamMonitoring outcomesClinical trialsInterventionLocal implementationTechnological evolutionTeamDynamic natureTrialsDeliveryCase exampleSystem
2023
Adoption of Emergency Department–Initiated Buprenorphine for Patients With Opioid Use Disorder
Gao E, Melnick E, Paek H, Nath B, Taylor R, Loza A. Adoption of Emergency Department–Initiated Buprenorphine for Patients With Opioid Use Disorder. JAMA Network Open 2023, 6: e2342786. PMID: 37948075, PMCID: PMC10638655, DOI: 10.1001/jamanetworkopen.2023.42786.Peer-Reviewed Original ResearchConceptsHealth care systemED initiationOpioid use disorderBuprenorphine initiationCare systemUse disordersEmergency Department-Initiated BuprenorphineSecondary analysisClinician's roleEmergency department initiationClinical decision support interventionClinical decision support toolProportional hazard modelingCare of patientsNetwork of cliniciansDecision support interventionsAdvanced practice practitionersDose-dependent mannerUnique cliniciansTime-dependent covariatesTrial interventionNonintervention groupED clustersMore effective interventionsNumber of exposures