2024
Resting-state functional MRI of the nose as a novel investigational window into the nervous system
Ponticorvo S, Paasonen J, Stenroos P, Salo R, Tanila H, Filip P, Rothman D, Eberly L, Garwood M, Metzger G, Gröhn O, Michaeli S, Mangia S. Resting-state functional MRI of the nose as a novel investigational window into the nervous system. Scientific Reports 2024, 14: 26352. PMID: 39487180, PMCID: PMC11530622, DOI: 10.1038/s41598-024-77615-z.Peer-Reviewed Original ResearchConceptsFunctional MRICentral nervous system integrityAutonomic nervous system innervationNervous system innervationAir-tissue interfaceNervous system integrityNervous system activityAutonomic nervous system activityAwake miceResting-state functional MRIAir intakeAbundant vasculatureCSF spacesNervous systemHeart rateSystem activityMRIBrain vesselsClearance sitesResting-stateSystem integrationHealthy participantsNoseSignal lossBreathing rate
2009
Hypoxic Injury during Neonatal Development in Murine Brain: Correlation between In Vivo DTI Findings and Behavioral Assessment
Chahboune H, Ment LR, Stewart WB, Rothman DL, Vaccarino FM, Hyder F, Schwartz ML. Hypoxic Injury during Neonatal Development in Murine Brain: Correlation between In Vivo DTI Findings and Behavioral Assessment. Cerebral Cortex 2009, 19: 2891-2901. PMID: 19380380, PMCID: PMC2774398, DOI: 10.1093/cercor/bhp068.Peer-Reviewed Original ResearchConceptsChronic sublethal hypoxiaLow birth weight preterm infantsBirth weight preterm infantsHypoxia-induced modificationNeonatal rodent modelPreterm birth resultsWeight preterm infantsSignificant neurodevelopmental disabilitiesOpen field taskGreater locomotor activityPreterm infantsPreterm birthNeurodevelopmental consequencesBirth resultsHypoxic injurySomatosensory cortexCaudate putamenCallosal connectivityCorpus callosumBehavioral deficitsNeurodevelopmental disabilitiesRodent modelsNeonatal developmentDTI findingsSublethal hypoxia