2023
Implementing a Successful Tele-Nephrology Program for Rural Veterans
Bonegio R, Tuozzo K, Rifkin I, Kroll-Desrosiers A, Crowley S, Mattocks K, Moore D. Implementing a Successful Tele-Nephrology Program for Rural Veterans. Journal Of The American Society Of Nephrology 2023, 34: 729-729. DOI: 10.1681/asn.20233411s1729c.Peer-Reviewed Original Research
2015
The Tyrosine Kinase c-Src Specifically Binds to the Active Integrin αIIbβ3 to Initiate Outside-in Signaling in Platelets.
Wu Y, Span LM, Nygren P, Zhu H, Moore DT, Cheng H, Roder H, DeGrado WF, Bennett JS. The Tyrosine Kinase c-Src Specifically Binds to the Active Integrin αIIbβ3 to Initiate Outside-in Signaling in Platelets. J Biol Chem 2015, 290: 15825-15834. PMID: 25947380, DOI: 10.1074/jbc.M115.648428.Peer-Reviewed Original Research
2012
Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment.
Moore DT, Nygren P, Jo H, Boesze-Battaglia K, Bennett JS, DeGrado WF. Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment. Proc Natl Acad Sci U S A 2012, 109: 793-8. PMID: 22210111, DOI: 10.1073/pnas.1117220108.Peer-Reviewed Original Research
2011
Computational design of a β-peptide that targets transmembrane helices.
Shandler SJ, Korendovych IV, Moore DT, Smith-Dupont KB, Streu CN, Litvinov RI, Billings PC, Gai F, Bennett JS, DeGrado WF. Computational design of a β-peptide that targets transmembrane helices. J Am Chem Soc 2011, 133: 12378-81. PMID: 21780757, DOI: 10.1021/ja204215f.Peer-Reviewed Original ResearchTransmembrane communication: general principles and lessons from the structure and function of the M2 proton channel, K⁺ channels, and integrin receptors.
Grigoryan G, Moore DT, DeGrado WF. Transmembrane communication: general principles and lessons from the structure and function of the M2 proton channel, K⁺ channels, and integrin receptors. Annu Rev Biochem 2011, 80: 211-37. PMID: 21548783, DOI: 10.1146/annurev-biochem-091008-152423.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2010
NMR analysis of the alphaIIb beta3 cytoplasmic interaction suggests a mechanism for integrin regulation.
Metcalf DG, Moore DT, Wu Y, Kielec JM, Molnar K, Valentine KG, Wand AJ, Bennett JS, DeGrado WF. NMR analysis of the alphaIIb beta3 cytoplasmic interaction suggests a mechanism for integrin regulation. Proc Natl Acad Sci U S A 2010, 107: 22481-6. PMID: 21156831, DOI: 10.1073/pnas.1015545107.Peer-Reviewed Original ResearchRegulation of platelet beta 3 integrins.
Bennett JS, Moore DT. Regulation of platelet beta 3 integrins. Haematologica 2010, 95: 1049-51. PMID: 20595101, DOI: 10.3324/haematol.2010.024893.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2008
Protein-protein interactions in the membrane: sequence, structural, and biological motifs.
Moore DT, Berger BW, DeGrado WF. Protein-protein interactions in the membrane: sequence, structural, and biological motifs. Structure 2008, 16: 991-1001. PMID: 18611372, DOI: 10.1016/j.str.2008.05.007.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2006
Activation of platelet alphaIIbbeta3 by an exogenous peptide corresponding to the transmembrane domain of alphaIIb.
Yin H, Litvinov RI, Vilaire G, Zhu H, Li W, Caputo GA, Moore DT, Lear JD, Weisel JW, Degrado WF, Bennett JS. Activation of platelet alphaIIbbeta3 by an exogenous peptide corresponding to the transmembrane domain of alphaIIb. J Biol Chem 2006, 281: 36732-41. PMID: 17032655, DOI: 10.1074/jbc.M605877200.Peer-Reviewed Original ResearchArylamide derivatives as allosteric inhibitors of the integrin alpha2beta1/type I collagen interaction.
Yin H, Gerlach LO, Miller MW, Moore DT, Liu D, Vilaire G, Bennett JS, DeGrado WF. Arylamide derivatives as allosteric inhibitors of the integrin alpha2beta1/type I collagen interaction. Bioorg Med Chem Lett 2006, 16: 3380-2. PMID: 16678410, DOI: 10.1016/j.bmcl.2006.04.037.Peer-Reviewed Original Research
2002
Highly enantioselective phenylacetylene additions to both aliphatic and aromatic aldehydes.
Gao G, Moore D, Xie RG, Pu L. Highly enantioselective phenylacetylene additions to both aliphatic and aromatic aldehydes. Org Lett 2002, 4: 4143-6. PMID: 12423107, DOI: 10.1021/ol026921r.Peer-Reviewed Original ResearchBINOL-catalyzed highly enantioselective terminal alkyne additions to aromatic aldehydes.
Moore D, Pu L. BINOL-catalyzed highly enantioselective terminal alkyne additions to aromatic aldehydes. Org Lett 2002, 4: 1855-7. PMID: 12027631, DOI: 10.1021/ol025825n.Peer-Reviewed Original Research