2003
Comparative physiological and serotoninergic properties of pulvinar neurons in the monkey, cat and ferret
Monckton J, McCormick D. Comparative physiological and serotoninergic properties of pulvinar neurons in the monkey, cat and ferret. Thalamus & Related Systems 2003, 2: 239-252. DOI: 10.1016/s1472-9288(03)00022-0.Peer-Reviewed Original ResearchApplication of serotoninThalamocortical neuronsLow-threshold Ca2Pulvinar neuronsThreshold Ca2Hyperpolarization-activated cation currentSingle spike activityBasic electrophysiological propertiesDistinct firing modesProminent hyperpolarizationMembrane potassium conductanceSerotoninergic propertiesSignificant species-dependent differencesSpike activityCation currentMonkey neuronsElectrophysiological propertiesPotassium conductanceNeuronsPharmacological propertiesSerotoninMonkeysCatsPulvinarSpecies-dependent differences
1997
Functional Properties of Perigeniculate Inhibition of Dorsal Lateral Geniculate Nucleus Thalamocortical Neurons In Vitro
Sanchez-Vives M, McCormick D. Functional Properties of Perigeniculate Inhibition of Dorsal Lateral Geniculate Nucleus Thalamocortical Neurons In Vitro. Journal Of Neuroscience 1997, 17: 8880-8893. PMID: 9348355, PMCID: PMC6573089, DOI: 10.1523/jneurosci.17-22-08880.1997.Peer-Reviewed Original ResearchMeSH KeywordsAcetazolamideAnimalsAnticonvulsantsBaclofenBicucullineCerebral CortexConvulsantsElectrophysiologyFemaleFerretsGABA AgonistsGABA AntagonistsGamma-Aminobutyric AcidGeniculate BodiesMaleMembrane PotentialsNeural InhibitionNeural PathwaysNeuronsOrganophosphorus CompoundsPicrotoxinReceptors, GABA-AReceptors, GABA-BReceptors, PresynapticThalamic NucleiConceptsGABAB receptorsThalamocortical neuronsPGN neuronsGABAA receptorsThalamocortical cellsGABAB receptor-mediated IPSPsLocal applicationDorsal lateral geniculate nucleusReceptor-mediated IPSPsSynchronous slow oscillationsLow-intensity stimulationLow-threshold Ca2Lateral geniculate nucleusStrong activationPerigeniculate nucleusGeniculate nucleusIntracellular recordingsInhibitory influenceAction potentialsIntensity stimulationThreshold Ca2IPSPsNeuronsSpindle wavesPathological conditions
1995
Postnatal development of synchronized network oscillations in the ferret dorsal lateral geniculate and perigeniculate nuclei
McCormick D, Trent F, Ramoa A. Postnatal development of synchronized network oscillations in the ferret dorsal lateral geniculate and perigeniculate nuclei. Journal Of Neuroscience 1995, 15: 5739-5752. PMID: 7643215, PMCID: PMC6577643, DOI: 10.1523/jneurosci.15-08-05739.1995.Peer-Reviewed Original ResearchConceptsInhibitory postsynaptic potentialsLow-threshold Ca2PGN neuronsIntracellular recordingsAction potentialsSpindle wavesPostnatal developmentGABAA receptorsRelay cellsElectrophysiological propertiesGABAA antagonist bicuculline methiodideHigh-frequency burst dischargesThreshold Ca2Dorsal lateral geniculate nucleusFerret dorsal lateral geniculate nucleusSpindle wave generationNetwork oscillationsDorsal lateral geniculateAction potential firingLateral geniculate nucleusThalamocortical relay cellsSynchronized network oscillationsBarrages of EPSPsLGNd relay cellsHigh-frequency burstsRole of the ferret perigeniculate nucleus in the generation of synchronized oscillations in vitro.
Bal T, von Krosigk M, McCormick D. Role of the ferret perigeniculate nucleus in the generation of synchronized oscillations in vitro. The Journal Of Physiology 1995, 483: 665-685. PMID: 7776250, PMCID: PMC1157809, DOI: 10.1113/jphysiol.1995.sp020613.Peer-Reviewed Original ResearchConceptsExcitatory postsynaptic potentialsInhibitory postsynaptic potentialsPGN cellsSpindle wave generationLow-threshold Ca2Perigeniculate nucleusSpindle wavesPGN neuronsPostsynaptic potentialsRelay neuronsGABAA receptorsRelay cellsHigh-frequency burst dischargesThreshold Ca2Dorsal lateral geniculate nucleusNon-NMDA receptorsShort-duration inhibitory postsynaptic potentialMarked increaseLateral geniculate nucleusExtracellular recording techniquesVitro. 2GABAergic neuronsGABAergic receptorsGABAB receptorsProgressive hyperpolarization
1993
Mechanisms of oscillatory activity in guinea‐pig nucleus reticularis thalami in vitro: a mammalian pacemaker.
Bal T, McCormick D. Mechanisms of oscillatory activity in guinea‐pig nucleus reticularis thalami in vitro: a mammalian pacemaker. The Journal Of Physiology 1993, 468: 669-691. PMID: 8254530, PMCID: PMC1143849, DOI: 10.1113/jphysiol.1993.sp019794.Peer-Reviewed Original ResearchConceptsLow-threshold Ca2Nucleus reticularis thalamiRhythmic burst firingThreshold Ca2Reticularis thalamiBurst firingExtracellular Ca2Action potentialsOscillatory activityShort-latency burstsSingle spike activityVitro. 2Fast action potentialsNon-selective cationSlow ADPThalamic afferentsTonic dischargeNRT cellsIntracellular recordingsIntracellular injectionSpike AHPsSpike activitySingle neuronesExtracellular applicationReversal potential
1990
Functional implications of burst firing and single spike activity in lateral geniculate relay neurons
McCormick D, Feeser H. Functional implications of burst firing and single spike activity in lateral geniculate relay neurons. Neuroscience 1990, 39: 103-113. PMID: 2089273, DOI: 10.1016/0306-4522(90)90225-s.Peer-Reviewed Original ResearchConceptsExcitatory postsynaptic potentialsAction potentialsSingle-spike modeThalamic neuronsPostsynaptic potentialsRelay neuronsRhythmic burstsExcitatory inputsLateral geniculate relay neuronsGeniculate relay neuronsPhasic excitatory inputPeripheral receptive fieldsSingle spike activityPeriods of drowsinessLow-threshold Ca2Slow-wave sleepThalamocortical relay neuronsIncoming excitatory inputsHigh-frequency burstsFiring modesNeuronal activityWave sleepSpike activityThreshold Ca2Neurons